Central Nervous System News and Research

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Study shows rapid transformation in multiple sclerosis treatment in Finland

A registry study led by the University of Oulu examined the early-stage treatment of relapsing-remitting multiple sclerosis (MS) in Finland between 2013 and 2022.

19 Feb 2025

Neuroestrogens likely contribute to appetite regulation

Although a woman's ovaries produce the most estrogen, various types of estrogen are also synthesized throughout different tissues in the body, including the brain's neurons.

19 Feb 2025

Study shows promise for new treatment approach for multiple sclerosis

A sponge-like implant in mice helped guide a treatment that slowed or stopped a degenerative condition similar to multiple sclerosis in humans. It also gave University of Michigan researchers a first look at how primary progressive multiple sclerosis, the fastest-progressing version of the disease, attacks the central nervous system early on.

19 Feb 2025

Researchers identify MLC1 as potential target in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by the immune system. B cells, which are a type of white blood cell, play a role in the development of MS and are thus a target for therapies.

18 Feb 2025

Breakthrough technology enables mRNA delivery across the blood-brain barrier

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

17 Feb 2025

Discovery of gene silencer offers hope for autosomal dominant leukodystrophy

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating and fatal progressive neurological disease.

13 Feb 2025

Air pollution harms cognition just hours after exposure, study finds

New research shows that inhaling polluted air for just an hour can impair cognitive abilities like attention and emotional recognition within four hours, highlighting the urgent need for cleaner air policies.

11 Feb 2025

Insilico Medicine announces preclinical drug discovery benchmarks from 2021 to 2024

Insilico Medicine ( "Insilico") , a clinical stage generative artificial intelligence (AI)-driven biotechnology company today announced a set of preclinical drug discovery benchmarks from the 22 developmental candidate nominations achieved by its platform from 2021 to 2024.

11 Feb 2025

Innovative brain tumor model offers hope for personalized cancer treatments

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible.

11 Feb 2025

New method provides accurate measurement of drug permeability across the blood-brain barrier

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from potentially dangerous substances and microbes.

11 Feb 2025

Tick-borne encephalitis emerges in Britain: Experts urge vigilance

Tick-borne encephalitis virus (TBEV) has now been confirmed in locally acquired human cases in the U.K., with evidence of established transmission in British tick populations. Increased surveillance and clinician awareness are crucial to detecting and managing this emerging threat.

10 Feb 2025

Insilico Medicine develops highly selective FGFR2/3 dual inhibitor for cancer treatment

Fibroblast growth factor receptors (FGFRs) are critical drivers of oncogenesis in various solid tumors, including urothelial carcinoma, hepatocellular carcinoma, ovarian cancer and lung adenocarcinoma.

7 Feb 2025

Opioid δ-receptor agonists show promise for treating IBS-like symptoms

Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and reducing stress-induced hypermotility.

7 Feb 2025

Study could pave the way for routine eyecare imaging as a disease screening tool

Researchers have conducted one of the largest eye studies in the world to reveal new insights into retinal thickness, highlighting its potential in the early detection of diseases like type 2 diabetes, dementia and multiple sclerosis.

5 Feb 2025

New drug class may help alleviate IBS symptoms by targeting the central nervous system

Irritable bowel syndrome (IBS) is a common digestive disorder that affects the intestine, causing symptoms such as abdominal pain, bloating, gas, and changes in bowel habits, including diarrhea, constipation, or both.

5 Feb 2025

Neurostimulation improves movement in adults with spinal muscle atrophy

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease.

5 Feb 2025

How exercise affects appetite in obese men

Researchers examine how appetite-associated factors impact appetite perception in obese males.

3 Feb 2025

X-ray tomography reveals the gut-brain connection in Alzheimer's

Scientists led by the Institute of Nanotechnology in Italy, in collaboration with the ESRF, the European Synchrotron in Grenoble, France, have discovered how X-ray micro- and nano- tomography can provide clues on the processes that link the gut neurons with those in the brain and may trigger Alzheimer's.

31 Jan 2025

Map highlights diagnosis gaps for deadly CNS infections in HIV patients in Africa

A map of deadly infectious diseases known to attack the central nervous system (CNS) of people who are already suffering with HIV has unearthed diagnosis "blank spots" in Africa, according to research published today in The Lancet Global Health .

29 Jan 2025

Early detection of tumor spread improves treatment outcomes

A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University succeeded in the diagnosis of leptomeningeal disease in diffuse midline gliomas by detecting H3K27M-mutant droplets from circulating tumor DNA of cerebrospinal fluid taken from these patients.

27 Jan 2025