Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New computational method reconstructs how cells decide their fate

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate.

30 Dec 2025

Epigenetic clocks accurately predict age from human skeletal muscle

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 26, 2025, titled "Epigenetic aging signatures and age prediction in human skeletal muscle."

30 Dec 2025

Researchers explore why Alzheimer's affects men and women differently

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

Researchers create the most detailed 3D maps of the human genome

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome's three‑dimensional organization across time and space, according to a new study published in Nature.

22 Dec 2025

Altered stress signaling helps explain relapse in alcohol use disorder

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain-and offers insights on developing drugs to treat this condition.

22 Dec 2025

Fatty diets reprogram hepatocytes and increase liver cancer risk

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.

22 Dec 2025

Skin and internal organs sense cold through different molecular pathways

A research team led by Félix Viana, co-director of the Sensory Transduction and Nociception laboratory at the Institute for Neurosciences (IN), a joint research centre of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has demonstrated that the body uses different molecular mechanisms to detect cold in the skin and in internal organs.

19 Dec 2025

New open-source tool maps gene regulation networks in cancer

University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene regulation networks with applications in cancer survival analysis.

19 Dec 2025

DNA twisting controls how cells respond to estrogen

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the body changes so much during menopause. This is because estrogens regulate hundreds of genes.

19 Dec 2025

New genetic insights could lead to treatments for Candida auris

Scientists have discovered a genetic process which could unlock new ways to treat mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.

19 Dec 2025

Genes and biological networks that drive long COVID risk

This study merges causal genetics and network theory, revealing 32 genes linked to long COVID, offering insights for diagnostics and personalized therapies.

19 Dec 2025

Junk' DNA may hold new clues to Alzheimer’s disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

18 Dec 2025

New research highlights varied cold perception across body tissues

Universidad Miguel Hernández de Elche A research team led by Félix Viana, co-director of the Sensory Transduction and Nociception laboratory at the Institute for Neurosciences (IN), a joint research center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has demonstrated that the body uses different molecular mechanisms to detect cold in the skin and in internal organs.

18 Dec 2025

Opposing protein forces fine tune mRNA stability in human cells

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

16 Dec 2025

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance demonstrated in studies in mice that could lay the groundwork for safer, more precise treatments for cancer and other diseases.

16 Dec 2025

Scientists map how cinnamon’s bioactives interact with cancer signaling

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

15 Dec 2025

Australian scientists uncover key genetic drivers behind long COVID

Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.

15 Dec 2025

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

13 Dec 2025

Engineering muscle stem cells for sustainable cultured meat production

The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible tissues. Muscle stem cells, or satellite cells, are central to this process due to their ability to regenerate and form muscle fibers.

13 Dec 2025

External signals control oncolytic bacteria for precise cancer therapy delivery

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic delivery. This review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.

13 Dec 2025