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Healthy glial cell transplants slow Huntington’s disease progression

Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan.

17 Jun 2025

Understanding the role of astrocytes in depression and neuroinflammation

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness.

13 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Study links reelin to cocaine-induced brain and behavior changes

Cocaine, a drug of abuse, activates just a portion - 10 to 20 percent - of the neurons in the brain's nucleus accumbens, a critical region linked to motivation and addiction.

9 Jun 2025

Study uncovers brain regions that help differentiate imagination from reality

Areas of the brain that help a person differentiate between what is real and what is imaginary have been uncovered in a new study led by UCL researchers.

6 Jun 2025

New retinal prosthesis restores vision in blind mice and detects near-infrared light in macaques

A new prosthesis for the retina weaved with nanowires partially restored vision in blind mice and allowed detection of near-infrared light in macaques, according to a new study.

6 Jun 2025

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

Integrating discoveries with translational science to transform Alzheimer's care

At the 12th annual Helen and Robert Appel Alzheimer's Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer's disease is diagnosed and treated.

4 Jun 2025

UC Irvine researchers uncover altered RNA processing in ALS

UC Irvine researchers conducted a study to better understand the molecular basis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder in which patients lose the ability to move, becoming weak and wheelchair bound before dying because they can no longer breathe.

3 Jun 2025

Pitt researchers challenge a decades-old assumption about brain plasticity

A new study from Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites - not a shared site - to achieve different types of plasticity.

3 Jun 2025

How does norepinephrine influence anxiety-related behaviours?

Discover how microscopy revealed the influence norepinephrine has on anxiety.

From Bruker Nano Surfaces and Metrology 3 Jun 2025

Molecular stress makes old neurons vulnerable to neurodegenerative diseases

As the global population ages, the risk of developing neurodegenerative diseases such as dementia, Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) continues to rise. But the molecular mechanisms behind the deterioration of brain cells have remained elusive.

2 Jun 2025

Decade-long brain study offers new insights into aging

Researchers from The University of Texas at Dallas' Center for Vital Longevity (CVL) have released the full dataset from a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically healthy paths from those indicating a likelihood of decline.

28 May 2025

Basal ganglia neurons precisely regulate complex movement timing

Neurons deep in the brain not only help to initiate movement-they also actively suppress it, and with astonishing precision.

28 May 2025

Astrocytes may contribute to memory storage in the brain

The human brain contains about 86 billion neurons. These cells fire electrical signals that help the brain store memories and send information and commands throughout the brain and the nervous system.

27 May 2025

Stress-induced sleep may hold the key to faster recovery

A new Neuron perspective reveals that stress can both disrupt and promote sleep, with specific brain circuits making stress-induced sleep a potential tool for recovery. This insight may lead to innovative approaches for building resilience and treating stress-related disorders.

25 May 2025