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ALL ALS Consortium creates a central information hub to accelerate ALS research

The Access for All in ALS (ALL ALS) Consortium announced the launch of its official website, creating a central hub for information about its initiatives and clinical research studies. ALL-ALS.org is designed to inform and engage researchers, clinicians, and current and prospective study participants.

31 Mar 2025

Hedonic eating fades with obesity—but neurotensin helps bring it back

Chronic high-fat diets blunt the brain’s pleasure response to rich foods by impairing NAcLat→VTA signaling in mice. Neurotensin dysfunction underlies this effect, but restoring its signaling revives hedonic feeding and reduces obesity symptoms.

30 Mar 2025

Artificial neurons learn independently in self-organized networks

Novel artificial neurons learn independently and are more strongly modeled on their biological counterparts.

28 Mar 2025

New insights into how glutamate opens brain cell signaling channels

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter.

28 Mar 2025

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.

28 Mar 2025

Dopamine neurons play a central role in sustaining hedonic eating

A previously overlooked dopamine-producing brain circuit drives hedonic eating, or eating for pleasure, according to a new study in mice.

27 Mar 2025

New insights into how sleep reorganizes neuronal activity for better memory

Why is sleep so important for learning and memory? Neuroscientists from the Csicsvari group at the Institute of Science and Technology Austria (ISTA) provided new insight into this essential function by monitoring neuronal activity in rat brains for up to 20 hours of sleep following spatial learning.

24 Mar 2025

Research reveals how dendrites connect memories in the brain

If you've ever noticed how memories from the same day seem connected while events from weeks apart feel separate, a new study reveals the reason: Our brains physically link memories that occur close in time not in the cell bodies of neurons, but rather in their spiny extensions called dendrites.

22 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

Study reveals the structural underpinnings of memory formation in the mouse brain

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain.

20 Mar 2025

Deep sleep may protect against neurodegeneration

Sleep disturbances may accelerate neurodegeneration, but whether they cause or result from disease remains unclear. Improving sleep quality could help protect against cognitive decline and brain aging.

20 Mar 2025

Brain dynamics during male sexual behavior revealed

To uncover what drives sexual behavior in animals, researchers studied the brain activity of male mice throughout the series of actions involved in sex leading up to ejaculation.

19 Mar 2025

UCLA Health discovers drug that mimics stroke rehabilitation effects in mice

A new study by UCLA Health has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice, following from human studies.

19 Mar 2025

Study sheds light on why women experience chronic pain more than men

A new study led by University of Calgary professor Dr. Tuan Trang, PhD, may help to explain why there is an over-representation of women experiencing chronic pain compared to men.

18 Mar 2025

Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

Study examines the mechanisms behind long-term consequences of childhood stress

Early-life adversity affects more than half of the world's children and is a significant risk factor for cognitive and mental health problems later in life.

17 Mar 2025

MIT engineers develop efficient method to convert skin cells into neurons

Converting one type of cell to another - for example, a skin cell to a neuron - can be done through a process that requires the skin cell to be induced into a "pluripotent" stem cell, then differentiated into a neuron.

13 Mar 2025

Study uncovers new insights into pain pathways linked with temporomandibular joint disorders

A groundbreaking study has uncovered new insights into the pain pathways associated with temporomandibular joint (TMJ) disorders.

13 Mar 2025

Diterpenes show promise in regenerating neurons after brain injury

Researchers from the University of Seville and the University of Cadiz, coordinated by the professors of Physiology Pedro Núñez-Abades and Carmen Castro, have demonstrated that the use of diterpenes facilitates repopulation with new neurons in brain regions damaged by traumatic injuries.

13 Mar 2025

Study reveals dopamine's role in reducing the value of reward memories

New research out of Michigan State University expands on current understanding of the brain chemical dopamine, finding that it plays a role in reducing the value of memories associated with rewards.

12 Mar 2025