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New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Universal CAR T cell therapy shows promise for aggressive T cell cancers

A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international phase 1/2 clinical trial led by researchers at Washington University School of Medicine in St. Louis.

31 May 2025

New trial offers hope for men with aggressive prostate cancer

Many men with aggressive prostate cancer can experience a high rate of recurrence despite treatment.

30 May 2025

New app can help improve quality of life for caregivers of bone marrow transplant patients

A new study by investigators from Mass General Brigham showed that a new app they created can help improve the quality of life for caregivers of patients undergoing bone marrow transplant (BMT).

30 May 2025

New four drug combination sets new standard in myeloma care

A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical Oncology, held May 30 through June 3 in Chicago.

29 May 2025

Necrosis may hold the key to unlocking longevity and space health solutions

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study from researchers at UCL, drug discovery company LinkGevity and the European Space Agency (ESA).

29 May 2025

New biomarker identified for predicting microvascular health of the kidneys

In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

27 May 2025

New vascularized model of stem cell islets promises to improve diabetes research

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

23 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Mayo Clinic discovery may help preserve donor hearts longer

A new discovery by Mayo Clinic researchers could mean more donor hearts are available for heart transplant, giving more people a second chance at life.

19 May 2025

New partnership aims to advance treatments for blood disorders and leukemia

A new frontier into advancing treatments for children and adults with bone marrow failure, leukaemia and other blood disorders will be achieved under a new partnership between Murdoch Children's Research Institute (MCRI) and US biotechnology company Retro Biosciences.

19 May 2025

World's first-in-human bladder transplant marks milestone in urologic surgery

Surgeons from Keck Medicine of USC and UCLA Health have performed the world's first-in-human bladder transplant.

18 May 2025

Ochsner's kidney transplant program earns national ELITE Status

Ochsner Health proudly shares its kidney transplant program, part of the Ochsner Transplant Institute, has been awarded ELITE Status within the credentialed Programs of Excellence transplant network by INTERLINK COE Networks & Programs.

16 May 2025

Study sheds light on public attitudes about transplant allocations

Becoming an organ donor has never been easier. Registration is available online when renewing a driver's license or, for iPhone users, through an app.

15 May 2025

Customized CRISPR gene editing therapy successfully treats infant with rare disease

In a historic medical breakthrough, a child diagnosed with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy by a team at Children's Hospital of Philadelphia (CHOP) and Penn Medicine.

15 May 2025

Palliative care for cardiovascular conditions may help relieve symptoms and improve quality of life

Palliative care may help relieve symptoms and improve quality of life for people with cardiovascular disease and ensure that treatment is aligned with the patient's personal beliefs and values throughout all stages of illness, whether they are hospitalized in a cardiac intensive care unit or receiving outpatient care, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

15 May 2025

Cardiac MRI could help detect lamin heart disease

Magnetic resonance imaging (MRI) scans of the heart could help to detect a life-threatening heart disease and enable clinicians to better predict which patients are most at risk, according to a new study led by UCL (University College London) researchers.

14 May 2025

Low-dose rapamycin shows promise for enhancing healthspan in older adults

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 4, 2025, titled "Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results."

7 May 2025

Comprehensive treatment approach helps patients manage rheumatoid arthritis

Although rheumatoid arthritis is an autoimmune disease with no cure, a tailored, multidisciplinary treatment approach at Cedars-Sinai's Inflammatory Arthritis Clinical Center helps patients get back to the activities they enjoy.

7 May 2025

Anal cancer rates increasing among older white and Hispanic women in the U.S.

Anal cancer has been steadily increasing in the United States, with the biggest jumps among older women, especially white and Hispanic women - a shift that challenges assumptions about high-risk groups and who should be screened, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025