Antigen News and Research

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CAR T-cell therapy may be viable treatment option for heart disease

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease.

12 Sep 2019

Non-invasive accurate blood test for prostate cancer

For men, one of the most dreaded moments could be hearing, “We’re not yet sure, but your PSA is high; you’ll have to come for further tests.” This could start a chain of events which ends in the diagnosis of prostate cancer - including a prostate biopsy, and ending in a major surgery for prostate removal.

11 Sep 2019

Simple blood test found to efficiently, accurately detect aggressive prostate cancer

A new and simple blood test has been found to efficiently and accurately detect the presence of aggressive prostate cancer, according to research by Queen Mary University of London.

10 Sep 2019

Tiny fat bubbles hold key to rebooting the immune system and calming disease process

People living with inflammatory autoimmune disease could benefit from an 'immune system reboot', and researchers have isolated specific cells to target.

7 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

$15 million grant funds new effort to develop universal vaccine for strep throat infections

CARB-X, an international non-profit partnership of private, academic and government institutions, has awarded SutroVax, Inc., a Northern California-based biopharmaceutical company, with an award of up to $15 million to develop a universal vaccine for Group A Streptococcus, the bacteria that causes pharyngitis or strep throat.

4 Sep 2019

Bacterial endotoxin testing now offered by Perfectus Biomed

Endotoxins are toxins present within a bacterial cell wall that are released when a cell disintegrates. They are lipopolysaccharides (LPS) and are found within the outer membrane of the cell wall of Gram-negative bacteria. Endotoxins often consist of lipid A, a core oligosaccharide and the O-specific polysaccharide.

From Perfectus Biomed 3 Sep 2019

Discovery may help identify signs of type 1 diabetes earlier

A new study showed that there are significant differences in the MHC class II antigens on the insulin peptide that is deficient in type 1 diabetes mellitus (T1DM). These determine the response of the T cells to the insulin peptide that causes destruction of insulin.

2 Sep 2019

ATS publishes clinical guideline on laboratory diagnosis of fungal infections

The American Thoracic Society has published an official clinical guideline on laboratory diagnosis of fungal infections in pulmonary and critical care medicine in the Society's Aug. 30 American Journal of Respiratory and Critical Care Medicine.

30 Aug 2019

Novel immunotherapy method could overcome tumor immunity

Cancer immunotherapy is a form of treatment in which the body’s own immune cells are recruited to overcome the tumor. However, it is only useful in a few tumors, because of tumor immunity where tumor-associated immune cells work to protect the tumor against attack.

28 Aug 2019

Skin patch delivers melanoma medication in one minute

Researchers have developed a fast-acting skin patch that can deliver medication to treat melanoma in one minute.

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Super-powered immune cells to attack tumors

Ground-breaking immune therapy promises to deliver vital evidence in the fight against cancer as researchers from the Centre for Cancer Biology open a new clinical trial using genetically engineered immune cells to treat solid cancers.

23 Aug 2019

New insight into the immune system may help doctors to better fight cancer

Your immune system's natural killer cells recognize and attack two major kinds of danger - cells infected by viruses and cells affected by cancer.

20 Aug 2019

Type 1 diabetes linked to gut microbiome and genetic factors

A new study has revealed that the gut microbiome of children with a high genetic risk of developing type 1 diabetes is markedly different from those who have a low risk of the condition.

20 Aug 2019

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Children with increased genetic risk of type 1 diabetes have different gut microbiomes than those with low risk, a new study found.

20 Aug 2019

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they have developed a new gene-editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong and his group at Sejong University.

20 Aug 2019

New T cell detection method promises personalized immunotherapy for melanomas

An important new study shows that better T cell detection is now possible using revolutionary technology. T cells are a type of lymphocyte, which in turn belongs to the diverse family of immune cells. They take part in cancer fighting as well as in most other immune responses.

12 Aug 2019

New technique protects promising TB vaccine from heat damage

Scientists working on a new tuberculosis vaccine have achieved a major step forward by showing that a promising TB antigen and a novel vaccine adjuvant can be protected from heat damage with a technique developed at the University of Bath.

8 Aug 2019