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Children’s Hospital Colorado helps prove safety and efficacy of CF treatment in younger pediatric patients

Researchers at the Children's Hospital Colorado Breathing Institute, the largest pediatric cystic fibrosis (CF) clinical care center in the U.S., participated in the pivotal international multi-center Phase 3 clinical trial, sponsored by Vertex Pharmaceuticals Incorporated, leading to FDA approval of TRIKAFTA (elexacaftor/tezacaftor/ivacaftor), a highly effective CF treatment, for patients ages 6 through 11 who have at least one copy of the F508del mutation.

17 Aug 2021

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Now, a new study posted to the bioRxiv* preprint server focuses on functional immune memory to SARS-CoV-2, up to nine months in a Southeast Asian cohort, in the absence of re-infection.

16 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

In a recent study, a group of researchers determined the degree to which Pango lineages are distinguishable using spike-only nucleotide sequences.

16 Aug 2021

Research reveals increased risk of heart problems associated with night shift work

People who work night shifts are at increased risk of developing an irregular and often abnormally fast heart rhythm called atrial fibrillation (AF), according to research published in the European Heart Journal.

16 Aug 2021

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

In a recent bioRxiv* preprint research paper, a large group of US scientists demonstrate how a booster dose of the mRNA-1273 vaccine can substantially improve both the potency and range of neutralizing antibody responses and mediate protection against upper and lower airway infection by a range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern – even those relatively resistant to in vitro neutralization.

16 Aug 2021

Researchers take a key step toward a new concept for brain-computer interface system

Brain-computer interfaces (BCIs) are emerging assistive devices that may one day help people with brain or spinal injuries to move or communicate.

14 Aug 2021

Long-running wars, not the weather, are to blame for resurgent hunger in Africa, study says

For years, it seemed the world was making progress eliminating hunger. Then, starting in 2014, the trend slid back slowly and reversed in many nations; now, some 700 million people - nearly 9 percent of the world's population - go to bed hungry, according to the UN.

14 Aug 2021

Study tracks microbial population dynamics under prolonged starvation

A study of microbial populations under a prolonged period of starvation by Indiana University professor Jay T. Lennon and his laboratory could help researchers answer questions pertaining to chronic infections, the functioning of bacteria in the environment and the persistence of life itself.

14 Aug 2021

Excess COVID-19 cases, deaths in the U.S. may be attributable to PM2.5 pollution from wildfires

Thousands of COVID-19 cases and deaths in California, Oregon, and Washington between March and December 2020 may be attributable to increases in fine particulate air pollution (PM2.5) from wildfire smoke, according to a new study co-authored by researchers at Harvard T.H. Chan School of Public Health.

13 Aug 2021

Study examines the relationship between air pollution and labor productivity

Recent studies have highlighted the link between high levels of air pollution and poor health; for example, even short exposure to air pollutants can increase the risk of respiratory infections, heart disease and even lung cancer.

13 Aug 2021

How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Research debunks myth that COVID vaccination promotes mutations

A study conducted by researchers at the University of Maryland, USA, has highlighted the importance of coronavirus disease 2019 (COVID-19) vaccination in reducing the frequency of mutations in the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Aug 2021

SARS-CoV-2 detection by machine learning surface-enhanced Raman spectroscopy

Surface-enhanced Raman spectroscopy is a highly sensitive molecule characterization method, significantly more sensitive than ordinary Raman spectroscopy due to the excitation of Raman modes matching the plasmon resonance frequency of the surface metal utilized, usually gold, silver, or copper.

11 Aug 2021

High alcohol consumption increases risk of SARS-CoV-2 infection, finds US student study

A new study finds that heavy alcohol drinking is associated with an increase in the number of COVID-19 cases among American college students.

10 Aug 2021

Investigating the link between occupational noise exposure and cardiovascular disease

Occupational settings can involve exposure to loud noise, a known and preventable contributor to hearing loss.

10 Aug 2021

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

The spike protein comprises of two subunits: S1 subunit having the receptor-binding domain (RBD) that helps it to bind to the angiotensin-converting enzyme 2 (ACE2), which is present on the cell surface of the host, and the S2 subunit that helps in the fusion of the cellular membrane and the viral membrane.

9 Aug 2021

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

By retrieving 329,942 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) records from the GISAID database, researchers from a software company in Cambridge described genetic variability of SARS-CoV-2 in order to inform further studies. Their findings are currently available on the bioRxiv* preprint server while it undergoes peer review.

9 Aug 2021

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

Researchers in the United States, Australia and the UK have developed a novel method that enables the evolutionary ancestry (phylogeny) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be comprehensively searched for recombinant lineages.

8 Aug 2021

Long COVID may be due to persistent immune disturbances

A new study discusses abnormalities in the immune response following COVID-19 in samples collected from patients who have recovered from COVID-19.

8 Aug 2021

Frequency News and Research

Children’s Hospital Colorado helps prove safety and efficacy of CF treatment in younger pediatric patients

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

Research reveals increased risk of heart problems associated with night shift work

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

Researchers take a key step toward a new concept for brain-computer interface system

Long-running wars, not the weather, are to blame for resurgent hunger in Africa, study says

Study tracks microbial population dynamics under prolonged starvation

Excess COVID-19 cases, deaths in the U.S. may be attributable to PM2.5 pollution from wildfires

Study examines the relationship between air pollution and labor productivity

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Research debunks myth that COVID vaccination promotes mutations

SARS-CoV-2 detection by machine learning surface-enhanced Raman spectroscopy

High alcohol consumption increases risk of SARS-CoV-2 infection, finds US student study

Investigating the link between occupational noise exposure and cardiovascular disease

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

Long COVID may be due to persistent immune disturbances

Industry Focus eBook - Life Science Microscopy (3rd Edition) eBook

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The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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