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New polypeptide could provide universal protection against coronaviruses

Researchers in the United States have developed an inhibitor of the spike protein found on the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that limits its formation in host human cells that would otherwise be the source of newly generated virions.

11 Apr 2021

Toward a transformative therapy for sickle cell patients

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms.

9 Apr 2021

More new SARS-CoV-2 variants are highly likely

In a recent report posted to the bioRxiv preprint server, researchers from the United Kingdom and Uganda reveal unique protein features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relative to other representatives of Sarbecoviruses.

8 Apr 2021

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Scientists have been using genetics to track diseases for decades. Now, a team at Purdue University that typically tracks malaria spread in Southern and Central Africa is using its expertise to track COVID-19 in Indiana.

8 Apr 2021

Phase II of Singapore's National Precision Medicine strategy to begin in April 2021

Precision medicine is part of Singapore's Research, Innovation and Enterprise (RIE) 2025 strategic goal to transform and protect the health of every Singaporean.

7 Apr 2021

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

A team of scientists from the University of California Santa Cruz, USA, recently identified a novel variant (B.1.x) of SARS-CoV-2 that might be circulating in at least 20 US states and six countries globally.

7 Apr 2021

Advancing the Diagnosis and Treatment of Ovarian Cancer

In this interview, News-Medical talks to Dr. Marcos Quintela Vasquez about the work he is conducting regarding the diagnosis and treatment of ovarian cancer in partnership with Porvair Sciences.

From Porvair Sciences Limited 7 Apr 2021

Which SARS-CoV-2 spike mutants can evade T cell immunity?

A new study reports the capability of a new variant of the virus to escape specific cellular immunity, while possessing a higher binding affinity to the host cell binding receptor, the angiotensin-converting enzyme 2 (ACE2).

7 Apr 2021

Expert calls for swift action to avoid chronic health conditions caused by COVID-19

A tsunami of chronic health conditions as a result of the SARS-CoV-2 pandemic, especially cardiometabolic disease, may produce an enormous wave of death and disability that demands immediate, comprehensive strategies.

7 Apr 2021

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

A $10.8 million grant from the National Institutes of Health will enable an interdisciplinary team of researchers at the University of Arkansas and University of Arkansas for Medical Sciences to address the role of cell and tissue metabolism in rare and common diseases such as cancer, diabetes, obesity and mitochondrial disorders.

6 Apr 2021

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication.

6 Apr 2021

Researchers explore link between intestinal microbiota with colon cancer in patients with Lynch Syndrome

The researcher Gabriela Debesa, member of the research group at Simbiosis led by Andrés Moya at the Foundation for the Promotion of Health and Biomedical Research of Valencia Region (Fisabio), studied the relationship of the intestinal microbiota with colon cancer in patients with Lynch Syndrome (a hereditary illness that predisposes the development of cancer) using tissue samples in formalin and conserved in paraffin.

6 Apr 2021

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Scientists recently explored the transmission dynamics of currently circulating variants of SARS-CoV-2 in a southern African country. By analyzing the genomic sequences of these variants, they have identified a novel SARS-CoV-2 variant with multiple spike mutations. They have temporarily designated the variant A.VOI.V2.

6 Apr 2021

Researchers take key step toward new drugs and vaccines to combat COVID-19

Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein's interactions with SARS-CoV-2 genetic material.

6 Apr 2021

South Africa SARS-CoV-2 variant B.1.351 easily escapes Sputnik vaccine

A new preprint research paper posted to the medRxiv* server reports on vaccine resistance data that pushes the end of the pandemic further away.

6 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

Discovering DNA methylation from bacteria and microbiome using nanopore technology

Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial DNA methylation has important roles affecting clinically relevant phenotypes such as virulence, host colonization, sporulation, biofilm formation, among others.

5 Apr 2021

Can universal vaccines and treatments against future SARS-CoV-2 variants be developed?

A team of researchers from Saudi Arabia and Spain recently quantified the rapid evolution of SARS-CoV-2 by tracking the mutations of the virus globally, focusing on the receptor-binding domain (RBD) of the virus’s spike protein, which determines its infectivity.

5 Apr 2021

SARS-CoV-2 cryptic transmission modeling shows emergence of first wave in US and Europe

To analyze this cryptic transmission phase and the first wave of the pandemic that ensued, researchers from Italy, UK, and the US used a data-driven, spatial, stochastic, and age-structured epidemic model. They developed a mechanistic understanding of the evolution of the epidemic and estimated the time required for local transmission in various states and countries. The model developed by the team offers a statistical idea of SARS-CoV-2 introductions across European countries and many states in the US.

5 Apr 2021

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death.

5 Apr 2021

Genomic News and Research

New polypeptide could provide universal protection against coronaviruses

Toward a transformative therapy for sickle cell patients

More new SARS-CoV-2 variants are highly likely

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Phase II of Singapore's National Precision Medicine strategy to begin in April 2021

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

Advancing the Diagnosis and Treatment of Ovarian Cancer

Which SARS-CoV-2 spike mutants can evade T cell immunity?

Expert calls for swift action to avoid chronic health conditions caused by COVID-19

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Researchers explore link between intestinal microbiota with colon cancer in patients with Lynch Syndrome

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Researchers take key step toward new drugs and vaccines to combat COVID-19

South Africa SARS-CoV-2 variant B.1.351 easily escapes Sputnik vaccine

High expression of cell death genes may increase risk of early death from lung cancer

Discovering DNA methylation from bacteria and microbiome using nanopore technology

Can universal vaccines and treatments against future SARS-CoV-2 variants be developed?

SARS-CoV-2 cryptic transmission modeling shows emergence of first wave in US and Europe

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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