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PROTAC technology offers hope for treating castration-resistant prostate cancer

Announcing a new publication for Acta Materia Medica journal. Prostate cancer (PrCa) is the most prevalent urogenital cancer affecting men.

30 Jan 2025

New light-controlled tools offer real-time protein control in living cells

A research group at Umeå University has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells.

30 Jan 2025

Zika virus manipulates human skin to attract mosquitoes and boost transmission

Zika virus hijacks the skin of its human host to send out chemical signals that lure more mosquitoes to infect and spread the disease further, new research shows.

30 Jan 2025

Europe faces growing risk of polio despite ongoing vaccination efforts

An unusually high amount of poliovirus detections in several European countries in recent months has underscored the importance of keeping Europe polio-free, according to an editorial by European Centre for Disease Prevention and Control (ECDC) Director Pamela Rendi Wagner and World Health Organization (WHO) Regional Director for Europe Hans Kluge, which was published on Eurosurveillance. 'A future without polio remains our goal, but it is by no means a certainty', warn Rendi-Wagner and Kluge.

30 Jan 2025

Study identifies six genetic regions associated with anterior uveitis

An international study led by the University of Oulu and Oulu University Hospital has identified six genetic regions associated with the inflammation of the eye's iris, also known as anterior uveitis.

30 Jan 2025

Premature aging and cognitive decline could be detected by ECG tests and AI

Electrocardiogram tests may someday be used with an artificial intelligence (AI) model to detect premature aging and cognitive decline, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

Shorter telomeres linked to higher risk of age-related brain diseases

People with shorter protective caps at the end of their chromosomes (called telomeres) may be more likely to develop age-related brain diseases such as stroke, dementia and late-life depression (usually diagnosed at age 60 or older), according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

New research shines light on position-specific hallmarks of cancer

A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol Research Institute shows, for the first time, that within a tumor, the expression of the different hallmarks of cancer is not cell-specific, but rather position-specific.

30 Jan 2025

Genetic predisposition plays a role in how coffee tastes bitter to some more than others

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

29 Jan 2025

Study reveals strong link between childhood trauma and adolescent psychiatric disorders

A new study by a team of researchers from the UK and Brazil has revealed a strong connection between childhood trauma and the development of psychiatric disorders in adolescents living in low-and middle-income countries.

29 Jan 2025

Weekly diabetes injection could replace daily shots for lipodystrophy patients

Rutgers Health researchers have found that a weekly injection of diabetes medication could replace painful daily hormone shots for people with a rare genetic form of lipodystrophy that leaves patients with almost zero fat tissue, according to a study in The New England Journal of Medicine.

29 Jan 2025

Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

Study identifies potential gain of function mutation in retinoblastoma

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation."

29 Jan 2025

Genetic fingerprint could help predict antibiotic resistance in bacteria

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the World Health Organization estimates it could surpass cancer and heart disease as the leading cause of death as more bacteria develop defenses to the drugs designed to combat them.

29 Jan 2025

Trilobio introduces whole-laboratory automation platform at SLAS2025

Trilobio, developer of whole lab automation solutions for advancing biology research, today introduced the first version of its comprehensive robotics, lab equipment and software platform at the Society for Laboratory Automation and Screening conference, SLAS2025, alongside pilot customer data, demonstrating the platform's abilities in advancing research workflows.

From Trilobio 28 Jan 2025

Researchers identify brain circuit to reduce anxiety without side effects

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

28 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025

AI technology uncovers genetic factors and treatment options for Parkinson's

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

28 Jan 2025

Inherited gene mutation found to increase prostate cancer risk

A study of men with a family history of prostate cancer has discovered an inherited form of prostate cancer.

28 Jan 2025

NHS introduces genetic test to help reduce kidney failure risk for black donors

Hundreds of potential kidney donors of Black African and Black Caribbean heritage in the UK can now get a simple blood test to help reduce the risk of kidney failure.

28 Jan 2025