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The FDA seeks a new way to review old drugs without causing prices to soar

Chuck Peterson of Omaha, Nebraska, recently experienced a swollen, painful knuckle caused by arthritis. He got a prescription for colchicine.

15 Apr 2021

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Metabolic bone disease is a common complication of chronic kidney disease (CKD) and involves a broad spectrum of disorders of mineral metabolism that result in both skeletal and extra-skeletal consequences.

15 Apr 2021

COVID-19 deadlier than cars for over 40s, study finds

The study, which appeared on the pre-print server medRxiv, presented mortality rates and case-fatality rates for COVID-19 compared with other historic leading causes of death in the United States.

15 Apr 2021

Study identifies differences in biomarkers of inflammation between novel diabetes subgroups

Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future?

15 Apr 2021

Early monoclonal antibody therapies beneficial for COVID-19, finds study

A team of scientists recently conducted a large-scale study at Northwell Health, New York, USA, to evaluate the efficacy of neutralizing monoclonal antibody (MAB) therapies in preventing disease progression among patients with mild to moderate COVID-19. The findings reveal that the timing of initiating MAB therapy is a crucial factor in determining its efficacy against COVID-19.

14 Apr 2021

Study demonstrates that the main creators of SARS-CoV-2 mutations are vaccine-suppressed

A new research paper posted to the medRxiv* preprint server describes the changes in genomic sequence observed during the course of infection in a patient on the drug tacrolimus, along with steroids, both potent immunosuppressants, and who also received convalescent plasma treatment. These mutations were observed to occur within three weeks from infection.

14 Apr 2021

Mouse model closely replicates human NAFLD

Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant.

13 Apr 2021

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study.

13 Apr 2021

Biology of single-celled organisms reveals potential treatment target for COPD

In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.

13 Apr 2021

New research could change how doctors treat some patients with high blood pressure

New research led by a professor at NUI Galway is set to change how doctors treat some patients with high blood pressure - a condition that affects more than one in four men and one in five women.

13 Apr 2021

Baseline brain imaging should be considered in most metastatic kidney cancer patients, study suggests

The April 2021 issue of JNCCN - Journal of the National Comprehensive Cancer Network publishes new research from Memorial Sloan Kettering Cancer Center (MSK) and Gustave Roussy Institute, which suggests that baseline brain imaging should be considered in most patients with metastatic kidney cancer.

13 Apr 2021

ACE2 homology in laboratory and wild animals

A new preprint research paper posted to the bioRxiv server describes the conservation of an important receptor gene for the virus among several animal species that live in close contact or proximity to humans.

13 Apr 2021

Researchers uncover a new source of energy expending brown fat cells

A new source of energy expending brown fat cells has been uncovered by researchers at the Joslin Diabetes Center, which they say points towards potential new therapeutic options for obesity.

12 Apr 2021

UHN performed first double-lung transplant after COVID-19 in Canada

University Health Network has performed what is believed to be the first lung transplant in Canada on a patient whose lungs were irreparably damaged by COVID-19.

12 Apr 2021

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Experts have uncovered a new molecular reason why faecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and other similar diseases.

9 Apr 2021

Removing race modifiers in equations used to estimate kidney function

The American Society of Nephrology and the National Kidney Foundation announce the concurrent publication of "Special Article: Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report from the NKF-ASN Task Force" in the Journal of the American Society of Nephrology and the American Journal of Kidney Diseases.

9 Apr 2021

Toward a transformative therapy for sickle cell patients

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms.

9 Apr 2021

Researchers reveal blood clot risk and anticoagulation benefits in discharged COVID-19 patients

In the largest study of its kind, Feinstein Institutes for Medical Research and Northwell COVID-19 Research Consortium researchers reveal blood clot risk and anticoagulation benefits in hospitalized coronavirus disease 2019 (COVID-19) patients who have been recently discharged from the hospital.

9 Apr 2021

Study explains future ethical implications of brain organoid research

Stem cell research has allowed medicine to go places that were once science fiction. Using stem cells, scientists have manufactured heart cells, brain cells and other cell types that they are now transplanting into patients as a form of cell therapy.

9 Apr 2021

Effective response to HIV and COVID-19 pandemics requires accelerated research

The COVID-19 pandemic is affecting people with or at risk for HIV both indirectly, by interfering with HIV treatment and prevention services, and directly, by threatening individual health.

9 Apr 2021

Kidney News and Research

The FDA seeks a new way to review old drugs without causing prices to soar

Series of reviews discuss key issues in chronic kidney disease and bone disorders

COVID-19 deadlier than cars for over 40s, study finds

Study identifies differences in biomarkers of inflammation between novel diabetes subgroups

Early monoclonal antibody therapies beneficial for COVID-19, finds study

Study demonstrates that the main creators of SARS-CoV-2 mutations are vaccine-suppressed

Mouse model closely replicates human NAFLD

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

Biology of single-celled organisms reveals potential treatment target for COPD

New research could change how doctors treat some patients with high blood pressure

Baseline brain imaging should be considered in most metastatic kidney cancer patients, study suggests

ACE2 homology in laboratory and wild animals

Researchers uncover a new source of energy expending brown fat cells

UHN performed first double-lung transplant after COVID-19 in Canada

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Removing race modifiers in equations used to estimate kidney function

Toward a transformative therapy for sickle cell patients

Researchers reveal blood clot risk and anticoagulation benefits in discharged COVID-19 patients

Study explains future ethical implications of brain organoid research

Effective response to HIV and COVID-19 pandemics requires accelerated research

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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