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Longer looks: The Supreme Court and health law politics; Obama and drug shortages

There are eighty-two Planned Parenthood affiliates nationwide, operating nearly eight hundred clinics. Planned Parenthood says that one in five women in the U.S. has been treated at a Planned Parenthood clinic. Critics of Planned Parenthood, who are engaged in a sustained attack on the organization, say that most of those women are going to the clinics to have abortions, paid for, in violation of the Hyde Amendment, with taxpayer money.

18 Nov 2011

Blocking CaM kinase may help prevent cardiac rupture

For people who initially survive a heart attack, a significant cause of death in the next few days is cardiac rupture -- literally, bursting of the heart wall. A new study by University of Iowa researchers pinpoints a single protein as the key player in the biochemical cascade that leads to cardiac rupture.

18 Nov 2011

World's fastest program to examine interactions between molecules

Creating new, improved pharmaceuticals is sometimes very similar to cracking the code of a combination lock. If you have the wrong numbers, the lock won't open. Even worse, you don't know if your numbers are close to the actual code or way off the mark. The only solution is to simply guess a new combination and try again.

18 Nov 2011

IDSA supports 'Get Smart About Antibiotics Week'

With antibiotic-resistant infections increasingly common, and a dangerous lack of new infection fighters in the drug development pipeline, it's more important than ever to use existing antibiotics appropriately. This week, infectious disease experts are helping to educate consumers, health care providers, and policymakers about when antibiotics can help, when misuse of these lifesaving drugs can do more harm than good, and the tremendous need for new antibiotics to protect patients.

18 Nov 2011

South African public health experts urge countries to use TRIPS to produce generic drugs, IPS reports

South African public health experts from Medecins San Frontieres (MSF) South Africa and the Treatment Action Campaign (TAC) "are calling on governments to use legally available mechanisms to promote the production or import of generic drugs in their countries," Inter Press Service reports.

18 Nov 2011

Chloroquine-chemotherapy combination holds potential for metastatic breast cancer treatment

An anti-malaria drug used for more than 60 years is now being studied for use in breast cancer patients whose disease has not responded to traditional chemotherapy treatment.

18 Nov 2011

Scientists discover family of chemical compounds that could prevent malaria

A international team led by scientists from the Genomics Institute of the Novartis Research Foundation (GNF) and The Scripps Research Institute has discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease.

17 Nov 2011

Research shows how the bite of a small Texas snake causes extreme pain

Examining venom from a variety of poisonous snakes, a group of researchers at the University of California, San Francisco has discovered why the bite of one small black, yellow and red serpent called the Texas coral snake can be so painful.

17 Nov 2011

Viewpoints: Paul Starr on Obama, Romney and health reform; Glenn close on the need for mental health services

As we testified on Nov. 1 before the Joint Select Committee on Deficit Reduction, the principal driver of long-term federal deficits is the rapidly mounting cost of healthcare, particularly Medicare. ... Solving the U.S. debt crisis requires structural changes to slow Medicare's cost growth plus significant new revenue to accommodate the retirement of the baby boomers. Any plan without those two essential components should go back to the drawing board.

17 Nov 2011

Eli Lilly provides $4M in additional funding to IDRI for new TB therapies

Eli Lilly and Company today announced that it is providing more than $4 million in additional funding to the Infectious Disease Research Institute. The funding will allow IDRI to continue its early phase drug discovery efforts focused on identifying new and better therapies in the fight against tuberculosis, including multidrug-resistant strains known as MDR-TB.

17 Nov 2011

Psychiatric medication use soaring among women: Report

Attention Deficit Hyperactivity Disorder or ADHD commonly affects boys more than girls. However a new report shows that among adults, the numbers have changed with women’s use of ADHD medications risen over the past decade surpassing that of men.

17 Nov 2011

New possibilities for relief from digestive diseases

As a researcher in neurogastroenterology for 40 years, professor Khalil Bitar has spent his professional life studying the causes of perplexing and what frequently become embarrassing problems for humans—issues such as constipation, diarrhea and colon disease.

17 Nov 2011

Nanomedicine neither a cure-all nor a potential danger

Is the emerging field of nanomedicine a breathtaking technological revolution that promises remarkable new ways of diagnosing and treating diseases? Or does it portend the release of dangerous nanoparticles, nanorobots or nanoelectronic devices that will wreak havoc in the body? A new review of more than 500 studies on the topic concludes that neither scenario is likely. It appears in ACS' journal Molecular Pharmaceutics.

17 Nov 2011

20% of U.S. adults take psychiatric drugs

The medicating of Americans for mental illnesses continued to grow over the past decade, with one in five adults now taking at least one psychiatric drug such as antidepressants, antipsychotics and anti-anxiety medications, according to an analysis of pharmacy-claims data.

17 Nov 2011

VHIO, MGHCC sign tumor biomarker agreement

The President of the BBVA Foundation, Francisco Gonz-lez, Jose Baselga, Chief of Hematology/Oncology at Massachusetts General Hospital Cancer Center (MGHCC), and Andr-s de Kelety, Managing Director at the Vall d'Hebr-n Institute of Oncology (VHIO) in Barcelona, yesterday signed the agreement creating the BBVA Foundation Tumor Biomarkers Research Program.

17 Nov 2011

TNF inhibitors may minimally increase risk of serious infections

Biologic drugs have revolutionized treatment of autoimmune diseases during the past decade despite belief there is an increased risk for serious infections from using them. But new research from the University of Alabama at Birmingham Center for Education and Research on Therapeutics reveals that a class of biologics called tumor necrosis factor antagonists, or TNF inhibitors, may only minimally increase risk compared to more traditional therapies.

17 Nov 2011

Avraham raises $3M to advance ladostigil Phase II Alzheimer's trial

The drug, ladostigil, is a molecule that combines components from the existing drugs Azilect and Exelon. Teva's Azilect, for the treatment of Parkinson's disease, was developed by Prof. Emeritus Moussa Youdim of the Technion-Israel Institute of Technology. Azilect is the only anti-Parkinson's drug that has proven to have a disease-modifying effect. Novartis's Exelon was developed by Prof. Marta Weinstock-Rosin of Hebrew University to treat Alzheimer's disease.

17 Nov 2011

Cancer cells tap into natural recycling system to obtain energy

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that cancer cells tap into a natural recycling system to obtain the energy they need to keep dividing. In a study with potential implications for cancer treatments, Einstein researchers used genetic manipulation to turn off this recycling system within the walls of cells and stop both tumor growth and metastasis.

17 Nov 2011

Mannosides show promise against urinary tract infections

An experimental treatment for urinary tract infections has easily passed its first test in animals, alleviating weeks-long infections in mice in as little as six hours.

17 Nov 2011

Mycophenolate mofetil superior to azathioprine for lupus nephritis

A new large, international study finds that the immunosuppressant drug mycophenolate mofetil is superior to azathioprine, an older immunosuppressant, as a maintenance therapy for lupus nephritis.

17 Nov 2011