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Curia to Acquire US-based LakePharma, Expanding End-to-End R&D Capabilities and Scale for Biologics

Curia today announced it has entered into a definitive agreement to acquire LakePharma Inc.

From Curia 14 Jul 2021

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Niclosamide is an antihelminthic drug, historically used to treat tapeworm infestations, though has been investigated and repurposed for use against SARS-CoV-2. In a new study recently uploaded to the preprint server bioRxiv* by Garrett et al. (July 12, 2021), the drug demonstrates the ability to reorganize the lipid profile of SARS-CoV-2 infected Vero E6 cells, thereby limiting virus replication.

14 Jul 2021

Scientists identify existing drugs that may inhibit SARS-CoV-2 virus

The COVID-19 pandemic has caused more than 600,000 deaths in the United States since the start of 2020 and more than 4 million globally.

13 Jul 2021

Understanding the molecular mechanisms behind lung cancer relapse

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away.

13 Jul 2021

Curia to Acquire Integrity Bio, Expanding Biologic Formulation and Fill-Finish Capabilities

Curia today announced it has entered into a definitive agreement to acquire Integrity Bio, Inc., a privately held formulation and fill-finish organization.

From Curia 13 Jul 2021

Researchers gain new insights into the pathology of Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Scientists discover drug candidates for treating liver fibrosis among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies -- among pest control chemicals.

8 Jul 2021

Scientists discover potential marker for the success of immunotherapy in lung cancer patients

Lung cancer has the highest mortality rate of all cancers, and treatment options are extremely limited, especially for patients with oncogenic mutations in the KRAS gene.

8 Jul 2021

Researchers discover how to artificially produce healthy mucus

Many people instinctively associate mucus with something disgusting, but in fact, it has incredibly many valuable functions for our health. It keeps track of our important intestinal flora and feeds the bacteria.

8 Jul 2021

Using AI to find new pharmaceutical applications for natural products

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated.

7 Jul 2021

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

In a recent study published in the journal Science Immunology, scientists have revealed that the presence of CD8+ T cells against conserved epitopes of seasonal coronaviruses is associated with mild coronavirus disease 2019 (COVID-19). These immune cells exhibit a memory phenotype and provide protection against severe disease.

7 Jul 2021

Skin pigmentation mechanism confers major protection against UV-related cancers

A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).

7 Jul 2021

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

7 Jul 2021

Scientists unravel how cell death is initiated on a molecular level

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors.

6 Jul 2021

Plant compounds inhibit Mpro of SARS-CoV-2 and HCoV-229E in vitro

A group of researchers recently discussed their findings that a group of plant flavonols and dihydroflavonols exhibit antiviral efficacy against both SARS-CoV-2 and HCoV-229E.

6 Jul 2021

A new method for generating metabolic profiles of single cells

Scientists from the European Molecular Biology Laboratory and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells.

6 Jul 2021

Research team identifies a way to improve immune response during viral infections

Melbourne researchers have identified a way to improve the immune response in the face of severe viral infections.

6 Jul 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

Plant-based meat substitutes taste and chew remarkably similar to real beef, and the 13 items listed on their nutrition labels - vitamins, fats and protein -- make them seem essentially equivalent.

6 Jul 2021

New blood test for improved frontotemporal dementia diagnostics

A new study by researchers at the University of Eastern Finland shows for the first time that blood-based measurement of glial fibrillary acidic protein (GFAP) enables distinguishing patients with frontotemporal dementia from those with primary psychiatric disorders or healthy individuals.

6 Jul 2021

Molecule News and Research

Curia to Acquire US-based LakePharma, Expanding End-to-End R&D Capabilities and Scale for Biologics

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Scientists identify existing drugs that may inhibit SARS-CoV-2 virus

Understanding the molecular mechanisms behind lung cancer relapse

Curia to Acquire Integrity Bio, Expanding Biologic Formulation and Fill-Finish Capabilities

Researchers gain new insights into the pathology of Usher syndrome

Scientists discover drug candidates for treating liver fibrosis among pesticides

Scientists discover potential marker for the success of immunotherapy in lung cancer patients

Researchers discover how to artificially produce healthy mucus

Using AI to find new pharmaceutical applications for natural products

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Skin pigmentation mechanism confers major protection against UV-related cancers

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Scientists unravel how cell death is initiated on a molecular level

Plant compounds inhibit Mpro of SARS-CoV-2 and HCoV-229E in vitro

A new method for generating metabolic profiles of single cells

Research team identifies a way to improve immune response during viral infections

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

New blood test for improved frontotemporal dementia diagnostics

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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