Genetic News and Research

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Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity

Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk.

9 Jan 2008

Freeze-dried tendon grafts loaded with gene therapy may provide repair injured tendons

According to study data published today in the journal Molecular Therapy, a new graft technique may provide the first effective framework around which flexor tendon tissue can reorganize as it heals.

9 Jan 2008

BRCA1 and BRCA2 gene mutations and breast cancer

Breast cancer risk varies widely among women who are carriers of the BRCA1 and BRCA2 mutations, according to a new study published in the January 9, 2008, issue of the Journal of the American Medical Association (JAMA).

9 Jan 2008

Brain response differences found in way women with irritable bowel syndrome deal with pain

UCLA researchers found that women with IBS cannot effectively turn-off a pain modulation mechanism in the brain, which causes them to be more sensitive to abdominal pain, compared to women without IBS.

9 Jan 2008

New gene identified for cerebral venous thrombosis

Researchers have identified a new gene linked to cerebral venous thrombosis, a condition that causes blood clots in the veins of the brain that can lead to stroke.

8 Jan 2008

Discovery of 480 genes that control human cell division

A team of U.S., Israeli and German scientists used computational biology techniques to discover 480 genes that play a role in human cell division and to identify more than 100 of those genes that have an abnormal pattern of activation in cancer cells.

8 Jan 2008

Differentiation blocked in tumor stem cells

A new comparison of normal stem cells and cancer stem cells reveals that the cancer stem cells are abnormally trapped at an early stage of development.

8 Jan 2008

Children with high nitric oxide levels may still breathe easy

Nitric oxide (NO) is a gas released by cells in the lungs. When a person with allergies and/or asthma experiences an inflamed airway, the inflammatory cells release more NO and the NO levels increase. Due to this fact, fractional concentration of exhaled NO (FeNO) is an increasingly used tool in the diagnosis and management of asthma in children and adults.

7 Jan 2008

Eczema still on the increase in developing countries

Experts are warning policy makers that allergic disease might replace infectious disease as a major cause of ill health in cities undergoing rapid demographic changes in developing countries.

7 Jan 2008

Salinispora tropica marine bacterium points to new ways to treat human diseases

An unexpected discovery in marine biomedical laboratories at Scripps Institution of Oceanography at UC San Diego has led to new, key information about the fundamental biological processes inside a marine organism that creates a natural product currently being tested to treat cancer in humans.

7 Jan 2008

New understanding of cell's inner workings

A group of scientists in Princeton's Department of Ecology and Evolutionary Biology has uncovered a new biological mechanism that could provide a clearer window into a cell's inner workings.

7 Jan 2008

MIT researchers discover key to bird flu in humans

MIT researchers have uncovered a critical difference between flu viruses that infect birds and humans, a discovery that could help scientists monitor the evolution of avian flu strains and aid in the development of vaccines against a deadly flu pandemic.

7 Jan 2008

Comprehensive gene atlas underlying drug addiction

Using an integrative meta-analysis approach, researchers from the Center for Bioinformatics at Peking University in Beijing have assembled the most comprehensive gene atlas underlying drug addiction and identified five molecular pathways common to four different addictive drugs.

7 Jan 2008

Wisconsin now screens all newborns for severe combined immune deficiency

Wisconsin became the first state in the nation to screen all newborns for Severe Combined Immune Deficiency (SCID).

4 Jan 2008

The dopamine transporter gene influences alcohol withdrawal seizures

The physiological component of alcoholism is defined by tolerance and/or withdrawal: the more severe the dependency on alcohol, the more severe the clinical complications, such as greater intensity and/or complications of alcohol withdrawal.

4 Jan 2008

Scientists discover remarkable editing system for protein production

Even small mistakes made by cells during protein production can have profound disease effects, but the processes cells use to correct mistakes have been challenging to decipher.

4 Jan 2008

Pregnant women who are overweight/obese set the stage for offspring's obesity risk

The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants -- individuals under 11 months old -- is alarming.

4 Jan 2008

Peptide hormone found in the body prevents obesity and diabetes

A new study finds that a chemical found in the body is capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model.

4 Jan 2008

Gene therapy can reduce long-term drinking among rodents

Just as the risk of developing alcoholism is strongly influenced by genetic factors, mutations in gene coding - such as the aldehyde dehydrogenase (ALDH2*2) allele - also appear to protect against the risk.

4 Jan 2008

Down syndrome points to a new way of repressing cancer growth

Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model. Publishing in the Jan. 3 issue of Nature, the research team describes how trisomy 21, or Down syndrome in humans, can repress tumor growth.

4 Jan 2008