Membrane News and Research

RSS

Columbia researchers capture new detailed images of a temperature-sensing molecule

Columbia University researchers have captured new detailed images of a temperature-sensing molecule in its open, intermediate, and closed states.

21 Oct 2019

Researchers identify new mechanism by which cancer cells become resistant to ferroptosis

An international team of researchers has found a different way cancer becomes resistant to chemotherapy, suggesting a new target for drugs.

21 Oct 2019

Neutrophil extracellular traps could cause organ damage in malaria

Malaria is one of the world's deadliest infectious diseases: a small mosquito bite delivers numerous malaria parasites into the bloodstream. The human body defends itself valiantly against the parasite, which usually results in periodic flu-like symptoms and severe fever. Severe cases of the disease are accompanied by tissue damage and result in potentially fatal organ failure.

21 Oct 2019

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.

18 Oct 2019

Being obese may lead to fat accumulation in the lungs

Obesity is a growing health concern among children and adults across the globe. In the 2016 figures from the World Health Organization (WHO), 1.9 billion adults are overweight worldwide, and of these, over 650 million were obese.

17 Oct 2019

Newly established Precision Immunotherapy Clinic matches cancer patients to latest treatments

A third occurrence of colon cancer and a failed immunotherapy clinical trial left Gordon Levine confined to a wheelchair with large tumors in his right hip bone, spine and lung, plus smaller tumors throughout his body, including one that caused an obstruction in his colon.

17 Oct 2019

Is C-section good for childhood health?

A recent study published by the VATT Institute for Economic Research suggests that an unplanned CS performed for an indication which could perhaps have been avoided, only has a cause-effect relationship with asthma from early childhood, and not other long-term health outcomes.

17 Oct 2019

Novel antibiotic-free approach to tackle superbugs

Scientists have uncovered a novel antibiotic-free approach that could help prevent and treat one of the most widespread bacterial pathogens, using nanocapsules made of natural ingredients.

17 Oct 2019

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

New discovery paves way for better treatment of diabetes

Insulin, a hormone essential for regulating blood sugar and lipids, is normally produced by pancreatic β cells. In many people with diabetes, however, pancreatic cells are not (or no longer) functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections.

16 Oct 2019

Scientists decipher assembly line of glutamate receptors

Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian brain are glutamate receptors of the AMPA-type that generate the electrical signal required for fast communication between neurons.

16 Oct 2019

Study shows how electrostatic interactions can be regulated to control scroll-like cochleate structures

Northwestern Engineering materials science researchers have uncovered new insights into how electrostatic interactions can be regulated to attain and control scroll-like cochleate structures, which could inform how to capture and release macromolecules in a size-selective manner as part of future drug-delivery strategies.

16 Oct 2019

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.

15 Oct 2019

Simpler and direct method for producing lipidated proteins

Some of the body's proteins are not just made up of amino acids, they are also 'decorated' with lipid chains, which significantly influence the biological functions of the protein.

15 Oct 2019

Rapid and sensitive tracking of fat molecules in the body

Fats have earned a bad name as the source of all that is wrong with our hearts and blood vessels, not to mention our appearance. The dysfunctional handling of lipids or fats in the body is deeply involved in a multitude of metabolic upsets, such as obesity and cancer.

14 Oct 2019

'Tricked' bacteria open door to new antimicrobial therapies

Scientists have developed a new technique to trick bacteria into revealing hundreds of holes in their cell walls, opening the door for drugs that destroy bacteria’s cells.

14 Oct 2019

Research finds drugs for better long-term treatment of poorly controlled asthma

The waning effectiveness of drugs over time continues to be a major challenge in treating diseases, including asthma.

11 Oct 2019

Structural biology reveals 3D structure of asthma-linked receptor

A new study has laid bare the structure of a protein receptor called the CysLT1 receptor that is implicated in a range of allergic and cardiovascular conditions as well as some types of cancer. Published in Science Advances, the paper shows how the researchers used structural biology techniques to accomplish this feat.

10 Oct 2019

Research may help explain how liquid organelles in cells coexist without merging

New research may help to explain an intriguing phenomenon inside human cells: how wall-less liquid organelles are able to coexist as separate entities instead of just merging together.

10 Oct 2019

Membrane News and Research

Columbia researchers capture new detailed images of a temperature-sensing molecule

Researchers identify new mechanism by which cancer cells become resistant to ferroptosis

Neutrophil extracellular traps could cause organ damage in malaria

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

Being obese may lead to fat accumulation in the lungs

Newly established Precision Immunotherapy Clinic matches cancer patients to latest treatments

Is C-section good for childhood health?

Novel antibiotic-free approach to tackle superbugs

Study reveals new and surprising function of adenine nucleotide translocator

New discovery paves way for better treatment of diabetes

Scientists decipher assembly line of glutamate receptors

Study shows how electrostatic interactions can be regulated to control scroll-like cochleate structures

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

Simpler and direct method for producing lipidated proteins

Rapid and sensitive tracking of fat molecules in the body

'Tricked' bacteria open door to new antimicrobial therapies

Research finds drugs for better long-term treatment of poorly controlled asthma

Structural biology reveals 3D structure of asthma-linked receptor

Research may help explain how liquid organelles in cells coexist without merging

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo