Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Researchers at Cincinnati Children's Hospital Medical Center have developed a user-friendly, integrated platform for analyzing the transcriptomic and epigenomic "big data."

12 Aug 2015

Only 1 in 4 patients with ESRD in Georgia referred for kidney transplant evaluation

Only about one in four patients with end-stage renal disease in Georgia were referred for kidney transplant evaluation within 1 year of starting dialysis between 2005 and 2011, although there was substantial variability in referral among dialysis facilities, according to a study in the August 11 issue of JAMA.

12 Aug 2015

Janssen signs license agreement with Alligator Bioscience for immuno-oncology antibody

Janssen Biotech, Inc., one of the Janssen pharmaceutical companies of Johnson & Johnson announced today an exclusive, worldwide license agreement with Alligator Bioscience AB for ADC-1013, an immuno-oncology agent currently in Phase 1 clinical studies.

12 Aug 2015

Argos Therapeutics begins AGS-003 clinical trial in patients with metastatic renal cell carcinoma

Argos Therapeutics Inc., an immuno-oncology company focused on the development and commercialization of fully individualized immunotherapies for the treatment of cancer based on the Arcelis technology platform, today announced the initiation of a single-center pilot clinical trial of AGS-003 as a neoadjuvant immunotherapy in patients with localized renal cell carcinoma.

11 Aug 2015

Sorrento, TNK Therapeutics to exclusively license NanoVelcro CTC assay from CytoLumina and FetoLumina

Sorrento Therapeutics, Inc. announced today that it as well as its wholly-owned subsidiary TNK Therapeutics, Inc. have entered into a binding term sheet to exclusively license the NanoVelcro Circulating Tumor Cell (CTC) profiling assay technology from CytoLumina Technologies Corp. and FetoLumina Technologies Corp., two privately-held sister biotechnology companies in Los Angeles, California.

11 Aug 2015

Southern-style diet may increase risk of heart disease

Previous research from the University of Alabama at Birmingham has shown regularly consuming the "Southern-style" diet of fried foods, processed meats, foods high in fat and sugar-sweetened beverages, can lead to an increased risk of stroke and an increased risk of death for chronic kidney disease patients.

11 Aug 2015

Doctors suggest tips to ensure children's safety during school sports

Many children return to sports such as soccer, football, cross-country and volleyball when they return to school. Physicians in the Division of Sports Medicine at Cincinnati Children's Hospital Medical Center say preparation before the first day of practice is critical in helping to reduce the risk of injury.

11 Aug 2015

Mallinckrodt subsidiary to acquire Therakos for $1.325 billion

Mallinckrodt plc, a leading specialty biopharmaceutical company, and The Gores Group, a global investment firm, announced today that they have entered into a definitive agreement under which a subsidiary of Mallinckrodt will acquire Therakos, Inc. a leading immunotherapy company in a transaction valued at approximately $1.325 billion.

10 Aug 2015

Researchers develop new technology to track DNA-protein binding in live cells

Researchers have developed a new technology that precisely marks where groups of regulatory proteins called transcription factors bind DNA in the nuclei of live cells.

7 Aug 2015

LA BioMed researcher launches study to examine medication adherence among patients with dialysis

Taking medications as prescribed is challenging for many patients, and following doctors' orders regarding medication often varies over time and among different patients. The consequences of failing to follow the prescribed medication regimen range from mild to life-threatening, depending on the medication and the illness or condition being treated.

7 Aug 2015

Lund University researchers discovered 'main switch' that regulates cell invaginations

Lack of microinvaginations in the cell membrane, caveolae, can cause serious diseases such as lipodystrophy and muscular dystrophy. Researchers at Lund University in Sweden have now discovered a "main switch" that regulates the formation of these invaginations.

7 Aug 2015

Scientists use highly specialized X-ray crystallography technique to solve protein structure of HIFs

In a collaborative study between Sanford Burnham Prebys Medical Discovery Institute and the Argonne National Laboratory, scientists have used a highly specialized X-ray crystallography technique to solve the protein structure of hypoxia-inducible factors (HIFs), important regulators of a tumor's response to low oxygen (hyopoxia).

6 Aug 2015

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Joslin scientists have advanced understanding of how the cellular repair process is impaired in type 1 diabetes, which can cause cell death and lead to complications. The findings appear in the August issue of Cell Metabolism.

5 Aug 2015

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

The Cancer Research Institute, a nonprofit organization dedicated to fueling the discovery and development of immunotherapies for all forms of cancer, announced that it has committed more than $29.3 million in new funds to accelerate cancer immunology research and cancer immunotherapy clinical development in the United States, Australia, Canada, France, Sweden, Switzerland, and The Netherlands.

5 Aug 2015

Pharmaxis, Synairgen partner to develop LOXL2 inhibitor to treat idiopathic pulmonary fibrosis

Australian pharmaceutical company Pharmaxis Ltd and UK biotechnology company Synairgen plc today announced they have entered into a research collaboration to develop a selective inhibitor to the lysyl oxidase type 2 enzyme (LOXL2) to treat the fatal lung disease idiopathic pulmonary fibrosis (IPF).

5 Aug 2015

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix Corp. is pleased to announce the formation of an international Clinical Steering Committee for the RVX-208 "apabetalone" Phase 3 clinical trial BETonMACE assessing major adverse cardiac events (MACE) in high-risk vascular patients with diabetes mellitus and a recent Acute Coronary Syndrome event. BETonMACE is expected to start in the fall of 2015.

4 Aug 2015

Cincinnati Children's injury prevention coordinator offers school bus safety tips

According to the National Highway Traffic and Safety Administration, from 2004 through 2013, 1,344 people died in school transportation-related crashes—an average of 134 fatalities per year.

4 Aug 2015

Clinical dietitian suggests tips to help parents ensure healthy nutrition for children

Back to school means getting back into a routine that helps students achieve success in the new school year. Start the year off on solid footing by making good nutrition part of your child's schedule. Multiple studies have shown that good nutrition, improved hydration and proper sleep play a huge role in academic success.

4 Aug 2015

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

4 Aug 2015

Scientists develop artificial blood vessels that are resistant to blood clot formation

Scientists from ITMO University developed artificial blood vessels that are not susceptible to blood clot formation. The achievement was made possible by a new generation of drug-containing coating applied to the inner surface of the vessel.

4 Aug 2015

Nephrology News and Research

Further Reading

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Only 1 in 4 patients with ESRD in Georgia referred for kidney transplant evaluation

Janssen signs license agreement with Alligator Bioscience for immuno-oncology antibody

Argos Therapeutics begins AGS-003 clinical trial in patients with metastatic renal cell carcinoma

Sorrento, TNK Therapeutics to exclusively license NanoVelcro CTC assay from CytoLumina and FetoLumina

Southern-style diet may increase risk of heart disease

Doctors suggest tips to ensure children's safety during school sports

Mallinckrodt subsidiary to acquire Therakos for $1.325 billion

Researchers develop new technology to track DNA-protein binding in live cells

LA BioMed researcher launches study to examine medication adherence among patients with dialysis

Lund University researchers discovered 'main switch' that regulates cell invaginations

Scientists use highly specialized X-ray crystallography technique to solve protein structure of HIFs

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

Pharmaxis, Synairgen partner to develop LOXL2 inhibitor to treat idiopathic pulmonary fibrosis

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Cincinnati Children's injury prevention coordinator offers school bus safety tips

Clinical dietitian suggests tips to help parents ensure healthy nutrition for children

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Scientists develop artificial blood vessels that are resistant to blood clot formation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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