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Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

A recent article illustrated the structural and biochemical characteristics of the processing of SARS-CoV-2 polyproteins by Mpro.

1 Jun 2022

Study investigates an outbreak of SARS-CoV-2 among children and adults after attending an overnight summer camp

Researchers investigated a SARS-CoV-2 outbreak among individuals who attended an overnight summer camp in Texas in June 2021.

1 Jun 2022

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

seqWell today announced a partnership with Element Biosciences Inc., developer of the Element AVITI™ System.

From Element Biosciences 1 Jun 2022

Researchers discover how a workhorse protein keeps protein production on track

Cells produce proteins like little factories. But if they make too much at the wrong times it can lead to diseases like cancer, so they control production with a process called RNA interference (RNAi).

31 May 2022

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

Researchers compared the performance of a highly multiplexed mass spectrometry-based commercial assay to identify SARS-CoV-2 variants.

31 May 2022

Evidence on COVID-19 vaccine effectiveness and duration of protection against Omicron

Researchers reported the vaccine effectiveness and duration of immunity against SARS-CoV-2 Omicron.

31 May 2022

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

The loss of genome heterogeneity in CoVs leads to high viral fitness variants that adapt to the human host.

31 May 2022

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers demonstrated the sarbecovirus open reading frame 7a (ORF7a)-induced hindrance of the antigen presentation by the major histocompatibility complex class I (MHC-I) in hosts.

30 May 2022

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

A recent study published in The Lancet Microbe described the case of a non-vaccinated female coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 subvariants.

30 May 2022

Investigating post-COVID complaints after Delta versus Omicron variant infections

A new study discusses whether infection with the SARS-CoV-2 Omicron variant increases the risk of post-COVID complaints Delta infection.

30 May 2022

Fast-breeding sea urchin species could open new avenues for genetic research

Many people may not realize that the humble sea urchin is a titan when it comes to the study of biology. Now, researchers from Japan have discovered that sea urchins could help biological studies go further than ever before.

29 May 2022

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade predation.

27 May 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Researchers discover bifunctional lipopeptide antibiotic with a low resistance potential

Through bioinformatic prospecting, researchers discovered and synthesized a novel, naturally inspired bifunctional lipopeptide antibiotic with a low resistance potential.

27 May 2022

SARS-CoV-2 genome analysis could boost disease surveillance

Continued monitoring of the evolution of the virus that causes COVID-19 as the pandemic progresses could strengthen disease surveillance systems and aid preparedness for new variants, a study suggests.

27 May 2022

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

A case report published in the New England Journal of Medicine provides evidence that enterovirus D68 directly infects spinal cord neurons and that a corresponding robust immune response is present – a direct causation to the polio-like paralyzing illness, acute flaccid myelitis (AFM).

26 May 2022

A 6.4 million genome analysis predicts dominant SARS-CoV-2 variants

In this new study in the journal Science, researchers have developed a hierarchical Bayesian regression model, named, PyR0, which can analyze the complete set of publicly available SARS-CoV-2 genomes.

26 May 2022

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer's disease.

25 May 2022

Seven healthy habits may lower the risk of dementia in people with high genetic risk

Seven healthy habits and lifestyle factors may play a role in lowering the risk of dementia in people with the highest genetic risk, according to research published in the May 25, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

25 May 2022

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets.

25 May 2022

Genome News and Research

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

Study investigates an outbreak of SARS-CoV-2 among children and adults after attending an overnight summer camp

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

Researchers discover how a workhorse protein keeps protein production on track

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

Evidence on COVID-19 vaccine effectiveness and duration of protection against Omicron

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

Investigating post-COVID complaints after Delta versus Omicron variant infections

Fast-breeding sea urchin species could open new avenues for genetic research

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Researchers discover bifunctional lipopeptide antibiotic with a low resistance potential

SARS-CoV-2 genome analysis could boost disease surveillance

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

A 6.4 million genome analysis predicts dominant SARS-CoV-2 variants

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

Seven healthy habits may lower the risk of dementia in people with high genetic risk

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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