Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study elucidates how essential amino acid in humans acts as growth signal for cells

A recent study from the Laxman lab elucidates how a small metabolite and amino acid, methionine, acts as a growth signal for cells, by setting into motion a metabolic program for cell proliferation.

7 Jan 2019

Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in leukemia

Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

3 Jan 2019

Molecular signatures reveal why women are more likely to die from glioblastoma

Scientists have discovered molecular signatures that reveal why women are more likely to develop and die from the brain cancer, glioblastoma.

2 Jan 2019

Study finds how long-term memory encoded engram neurons are formed

While long-term memory is known to be encoded in specific neural cells, engram neurons, it has been unclear how these engram neurons are formed during training.

28 Dec 2018

Himalayan marmot genome offers clues to high-altitude adaptation

Himalayan marmots can survive at altitudes up to 5,000 meters in the Himalayan regions of India, Nepal, and Pakistan and on the Qinghai-Tibetan Plateau of China, where many of them face extreme cold, little oxygen, and few other resources.

27 Dec 2018

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. 20 in Genes & Development.

24 Dec 2018

Enhancers can be predicted through ChIP-seq technology

In genetics, an enhancer is a short region of DNA that can be bound by proteins to increase the likelihood that transcription of a particular gene will occur.

23 Dec 2018

Change in genome of Caucasians could explain higher rates of esophageal cancer

A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds.

21 Dec 2018

Elegant, low-cost approach enhances single-cell RNA sequencing

Droplet microfluidics has revolutionized single-cell RNA sequencing, offering a low-cost, high-throughput method for single-cell genomics. However, this method has been limited in its ability to capture complete RNA transcription information.

20 Dec 2018

New study reveals how fatty diet can lead to serious form of liver disease

A new study by Keck School of Medicine of USC researchers shows there's yet another reason to avoid a high fat, high cholesterol diet: It can trigger changes in the immune system that lead to a serious form of non-alcoholic fatty liver disease known as non-alcoholic steatohepatitis.

20 Dec 2018

Molecule discovery could hold the key to novel gene therapies for skin problems

Scientists at the University of Birmingham have discovered a protein that could hold the key to novel gene therapies for skin problems including psoriasis - a common, chronic skin disease that affects over 100 million people worldwide.

20 Dec 2018

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target for its prevention.

20 Dec 2018

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

Diets containing GM maize have no harmful effects on health or metabolism of rats

For six months, rats were fed a diet containing either GM maize (MON 810 or NK603) or non-GM maize, in varying concentrations.

14 Dec 2018

Gene Expression News and Research

Further Reading

Study elucidates how essential amino acid in humans acts as growth signal for cells

Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in leukemia

Molecular signatures reveal why women are more likely to die from glioblastoma

Study finds how long-term memory encoded engram neurons are formed

Himalayan marmot genome offers clues to high-altitude adaptation

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Enhancers can be predicted through ChIP-seq technology

Change in genome of Caucasians could explain higher rates of esophageal cancer

Elegant, low-cost approach enhances single-cell RNA sequencing

New study reveals how fatty diet can lead to serious form of liver disease

Molecule discovery could hold the key to novel gene therapies for skin problems

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

MUSC researchers identify potential therapeutic target for lung fibrosis

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Gut microbiome plays role in immune system regulation, study finds

Researchers identify link between mucus in the small airways and pulmonary fibrosis

New genetic testing method increases the precision of biomarker analysis

Researchers reveal how key transcription factor keeps the immune system in check

Study finds epigenetic differences in the brains of individuals with schizophrenia

Diets containing GM maize have no harmful effects on health or metabolism of rats

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