Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New study points to potential cure for addiction

The Akay Lab biomedical research team at the University of Houston is reporting in the journal Nature Scientific Reports that a possible cure for addiction may be found by following the pathways of significantly altered dopamine neurons in newborns who were chronically exposed to nicotine in utero.

7 Feb 2019

Chloroplast retrograde signaling attenuates elongation response to shade in plants

Plants need sunlight to feed and grow. Without light, the photosynthesis, the reaction by which the plant chloroplasts convert atmospheric CO2 and water into sugars and oxygen, cannot take place.

6 Feb 2019

Oxford Nanopore launches new cDNA Kits for its sequencing technology

Oxford Nanopore has launched new '109' cDNA Kits for its real-time, scalable sequencing technology. The new kits provide high throughput whilst generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA.

4 Feb 2019

Research opens up new therapeutic area to better manage chronic inflammatory diseases

Atherosclerosis is a disease defined by the accumulation of fatty deposits called plaques inside the arteries. It is a leading cause of heart attacks and strokes.

4 Feb 2019

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have linked the protein clusterin - for the first time -- to many different facets of cardiometabolic syndrome risk through its actions in the liver.

4 Feb 2019

Researchers use integrated data analysis to classify liver cancer

Liver cancer remains a major problem in healthcare globally, being the second most common cause of cancer-related death globally.

3 Feb 2019

E-cigarette flavorings shown to be harmful to the human lungs

Scientists have discovered that two chemicals that are commonly used to flavor e-cigarettes can cause harm to the human lungs.

1 Feb 2019

Chemicals used to flavor e-cigs may impair lung function

Two chemicals widely used to flavor electronic cigarettes may be impairing the function of cilia in the human airway, according to a new study led by Harvard T.H. Chan School of Public Health.

1 Feb 2019

Study reveals mechanisms responsible for embryonic development in fruit flies

The first moments of life unfold with incredible precision. Now, using mathematical tools and the help of fruit flies, researchers at Princeton have uncovered new findings about the mechanisms behind this precision.

1 Feb 2019

Warmer water and chemical exposure influence gene expression in North American fish

Warmer water temperatures, combined with low-level exposure to chemicals already known to be harmful to aquatic life, influence the expression of genes in the offspring of an abundant North American fish species - and threaten organisms whose sex determination is sensitive to water temperature.

1 Feb 2019

Fasting may boost human metabolic activity, research suggests

Fasting may help people lose weight, but new research suggests going without food may also boost human metabolic activity, generate antioxidants, and help reverse some effects of aging.

31 Jan 2019

Exercise-induced muscle changes could help boost mood in older adults, study suggests

New research suggests that exercise-induced muscle changes could help boost mood in older adults. The study is published ahead of print in the American Journal of Physiology--Cell Physiology.

31 Jan 2019

RNA-binding protein needed for development of pathological hypertrophy

In response to conditions such as high blood pressure and reduced blood flow to cardiac muscle, the adult heart can drastically enlarge, a process called pathological hypertrophy that preserves cardiac function in the short term but predisposes patients to intractable heart failure and sudden cardiac death if left untreated.

31 Jan 2019

New autism mouse model shows how epigenetic regulation impacts downstream gene

The causes of autism spectrum disorder are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced.

31 Jan 2019

Researchers discover how transcription factors find specific loci within DNA

Bioengineering experts have discovered that transcription factors which bind non-specifically to mitotic chromosomes are more efficient at finding their binding site within DNA during interphase.

30 Jan 2019

Researchers identify new therapeutic targets for kidney fibrosis

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population--and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis.

29 Jan 2019

Binge and heavy drinking may change DNA, resulting in greater desire for alcohol

Binge and heavy drinking may trigger a long-lasting genetic change, resulting in an even greater craving for alcohol, according to a Rutgers-led study in the journal Alcoholism: Clinical & Experimental Research.

29 Jan 2019

EZH2 mutations can be used as marker for diagnosing different types of cancers

Inside the cell, DNA is tightly wrapped around proteins and packed in a complex, 3D structure that we call "chromatin".

29 Jan 2019

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI) estimates that the prevalence of advanced AMD will grow to nearly 3 million by 2020.

29 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Gene Expression News and Research

Further Reading

New study points to potential cure for addiction

Chloroplast retrograde signaling attenuates elongation response to shade in plants

Oxford Nanopore launches new cDNA Kits for its sequencing technology

Research opens up new therapeutic area to better manage chronic inflammatory diseases

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

Researchers use integrated data analysis to classify liver cancer

E-cigarette flavorings shown to be harmful to the human lungs

Chemicals used to flavor e-cigs may impair lung function

Study reveals mechanisms responsible for embryonic development in fruit flies

Warmer water and chemical exposure influence gene expression in North American fish

Fasting may boost human metabolic activity, research suggests

Exercise-induced muscle changes could help boost mood in older adults, study suggests

RNA-binding protein needed for development of pathological hypertrophy

New autism mouse model shows how epigenetic regulation impacts downstream gene

Researchers discover how transcription factors find specific loci within DNA

Researchers identify new therapeutic targets for kidney fibrosis

Binge and heavy drinking may change DNA, resulting in greater desire for alcohol

EZH2 mutations can be used as marker for diagnosing different types of cancers

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

New class of antisense oligonucleotide therapeutics tested in humans

Industry Focus eBook - Biotechnology (4th edition) eBook

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Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

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The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy