Molecule News and Research

RSS

Humoral innate pattern recognition molecules against SARS-CoV-2

In a paper recently uploaded to the preprint server medRxiv by Garlanda et al. (June 8th, 2021), humoral pattern recognition molecules are explored for affinity towards SARS-CoV-2, contributing to unraveling the role of these molecules in COVID-19 disease progression.

13 Jun 2021

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans.

11 Jun 2021

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.

11 Jun 2021

Macrophages can aid tumor growth by distracting cancer-killing CD8+ T cells

A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system's cancer-killing CD8+ T cells.

11 Jun 2021

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized "killer" T cells.

10 Jun 2021

Researchers develop new method to make CRISPR gene editing more precise

CRISPR Researchers from Aarhus University and University of Copenhagen have developed a new method, which makes CRISPR gene editing more precise than conventional methods.

10 Jun 2021

Are pre-existing Vitamin D deficiencies linked to COVID-19 severity and mortality?

Even as the COVID-19 pandemic continues to spread and new variants of SARS-CoV-2 emerge, much remains to be known about why severity varies so unpredictably between individuals. A new study, released as a preprint on the medRxiv* server, elucidates the relationship between Vitamin D and COVID-19 severity.

10 Jun 2021

Rapamycin targets gut cells to alter the way DNA is stored

Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell.

10 Jun 2021

Cysteine persulfide found to be a new culprit in antibacterial resistance

A joint research project based in Kumamoto University, Japan has developed a new, highly sensitive analytical method that can detect degraded β-lactam antibacterial agents used in the treatment of bacterial infections.

9 Jun 2021

SARS-CoV-2 enzyme inhibitors among drugs screened for repurposing

A new bioRxiv* preprint describes the identification of some promising pharmaceutical compounds that could be developed as antiviral drugs against COVID-19.

9 Jun 2021

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

A new bioRxiv preprint attempts to make some sense of why certain people experience more severe forms of COVID-19 as compared to others by pointing to the increase in virus binding that occurs in the presence of smoking or vaping.

9 Jun 2021

New bacterium shows promise for treating type 2 diabetes, obesity

It all started, when Patrice Cani, FNRS researcher at University of Louvain (UCLouvain), and his team repeatedly observed that a bacterium (called Subdoligranulum) is almost absent in obese and diabetic people, while it is systematically present in healthy people. So, they decided to take a closer look at this "family" of bacteria.

9 Jun 2021

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

(BUSINESS WIRE)--QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reports.

9 Jun 2021

Researchers clarify cellular processes related to radiation resistance of pancreatic cancer cells

Pancreatic cancer is one of the deadliest cancer subtypes not just because it is difficult to diagnose early, but because it is inherently resistant to chemotherapy and radiotherapy.

8 Jun 2021

New resin acid molecules have promising properties as potential drugs against epilepsy

New molecules, developed by researchers at Linköping University, have promising properties as possible drugs against epilepsy.

8 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

NIH researchers identify novel small molecule inhibitors of SARS-CoV-2 variants

A team of scientists from the National Institutes of Health (NIH), USA, has recently identified six novel small molecule inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. The study is currently available on the bioRxiv* preprint server.

8 Jun 2021

New blood test helps monitor patient’s response to cancer treatment

Cancer patients who are undergoing targeted therapy can look forward to a new blood test that could tell their doctors whether the treatment is working, within one day after the start of the treatment.

8 Jun 2021

Natural products show promise against COVID-19 via iron chelation

Researchers at the University of Catania in Italy investigated whether natural compounds could prevent disease progression. Their study published in the Journal of Clinical Medicine found that iron chelators and protease inhibitors can counteract SARS-CoV-2 infection.

7 Jun 2021

The great promise of antiviral peptides against SARS-CoV-2

A new study, recently published in the journal Viruses, describes the impressive evidence for the role of antimicrobial peptidse (AMPs) in the treatment of COVID-19.

7 Jun 2021

Molecule News and Research

Humoral innate pattern recognition molecules against SARS-CoV-2

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

Macrophages can aid tumor growth by distracting cancer-killing CD8+ T cells

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

Researchers develop new method to make CRISPR gene editing more precise

Are pre-existing Vitamin D deficiencies linked to COVID-19 severity and mortality?

Rapamycin targets gut cells to alter the way DNA is stored

Cysteine persulfide found to be a new culprit in antibacterial resistance

SARS-CoV-2 enzyme inhibitors among drugs screened for repurposing

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

New bacterium shows promise for treating type 2 diabetes, obesity

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

Researchers clarify cellular processes related to radiation resistance of pancreatic cancer cells

New resin acid molecules have promising properties as potential drugs against epilepsy

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

NIH researchers identify novel small molecule inhibitors of SARS-CoV-2 variants

New blood test helps monitor patient’s response to cancer treatment

Natural products show promise against COVID-19 via iron chelation

The great promise of antiviral peptides against SARS-CoV-2

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News