Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Omeros' OMS721 granted FDA Fast Track designation for treatment of atypical hemolytic uremic syndrome

Omeros Corporation today announced that the U.S. Food and Drug Administration granted Fast Track designation to OMS721 for the treatment of patients with atypical hemolytic uremic syndrome (aHUS). OMS721 is the company's lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the key regulator of the lectin pathway of the immune system.

23 Jul 2015

UC San Diego researchers identify pivotal player in diabetic kidney disease

Tapping the potential of metabolomics, an emerging field focused on the chemical processes of metabolism, researchers at University of California, San Diego School of Medicine have identified a new and pivotal player in diabetic kidney disease.

23 Jul 2015

Mercy Medical Center named third best hospital in Maryland

U.S. News & World Report has released its annual "Best Hospital" rankings. This 26th annual edition includes information on nearly 5,000 hospitals nationwide. U.S. News & World Report named Mercy Medical Center in Baltimore as the third best hospital in Maryland, behind only the academic medical centers at Johns Hopkins and the University of Maryland. Mercy also retained its status from last year as the state's top-ranked community hospital.

23 Jul 2015

Tyrone Regional Health Network signs letter of intent to become member of Penn State Health

Tyrone Regional Health Network and Penn State Health have signed a letter of intent to enter into formal affiliation. With approval by organizational boards and state authorities, Tyrone Regional will become a member of Penn State Health.

22 Jul 2015

Research suggests that only one in three older Americans have diabetes under control

Only one in three older Americans have their diabetes under control as measured by guidelines set by the American Diabetes Association, new Johns Hopkins Bloomberg School of Public Health research suggests.

22 Jul 2015

Study examines link between use of diabetes drug pioglitazone and increased risk of bladder cancer

Although some previous studies have suggested an increased risk of bladder cancer with use of the diabetes drug pioglitazone, analyses that included nearly 200,000 patients found no statistically significant increased risk, however a small increased risk could not be excluded, according to a study in the July 21 issue of JAMA.

22 Jul 2015

UCLA Health's hospitals named among nation's best in U.S. News and World Report

UCLA Health's hospitals in Westwood and Santa Monica have been named to U.S. News and World Report's 2015-2016 Best Hospitals Honor Roll. UCLA, which previously ranked No. 5 in the country, tied for No. 3 this year.

22 Jul 2015

Dietary phosphate appears to cause spikes in blood phosphorus levels

Phosphates artificially added to dairy and cereal products appear to cause bigger spikes in blood phosphorus levels than naturally occurring phosphates, potentially putting harmful stress on kidneys. Too much dietary phosphate stiffens blood vessels, enlarges the heart and is bad for bones, but a new study by Houston Methodist researchers suggests it matters where the phosphates come from.

22 Jul 2015

Tamsulosin works better on large kidney stones

Tamsulosin works no better than placebo on small kidney stones, but does improve passage of more large kidney stones than placebo does. The results of this large clinical trial evaluating tamsulosin versus placebo were published online Friday in Annals of Emergency Medicine ("Distal Ureteric Stones and Tamsulosin: A Double-Blind, Placebo-Controlled, Randomized, Multi-Center Trial (The DUST Trial)").

22 Jul 2015

Researchers use iPSCs to explore new treatments for kidney disease

One promising way to treat diseased or damaged kidneys is cell therapies that include the transplantation of renal progenitor cells, which can then develop into the cells needed for full recovery. Acquiring a sufficient number of progenitor cells has been difficult, however, which is why scientists have considered induced pluripotent stem cells (iPSCs), since they can be expanded at significantly high levels and then differentiated into the progenitors.

22 Jul 2015

UC San Diego Health ranked again among nation's best hospitals by U.S. News & World Report

Once again, UC San Diego Health and its hospitals are ranked #1 in San Diego, and recognized among the best in the nation, by U.S. News & World Report for 2015-16. The annual U.S. News "Best Hospitals" rankings distinguish hospitals that excel in treating the most challenging health conditions.

21 Jul 2015

MU researcher receives $2.2 million grant to develop system to display clear blood pressure information

Physicians receive lots of information about patients in a short amount of time, and sometimes that information is scattered, disorganized or difficult to comprehend. Now, a researcher at the University of Missouri School of Medicine has received funding to develop a simpler and clearer system to display blood pressure information.

21 Jul 2015

New approach holds great promise for developing effective treatments for human mitochondrial diseases

Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.

21 Jul 2015

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA.

15 Jul 2015

Johns Hopkins endocrinologists propose new protocol for inpatient glucose management

Borrowing a page from a winning team’s playbook, Johns Hopkins endocrinologist Nestoras Mathioudakis, M.D., and his colleagues are taking on the topic of managing hospital patients’ diabetes.

15 Jul 2015

$Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients$

Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients

End-stage renal disease (ERSD) is the last stage of chronic kidney disease where the kidneys function at under 10 to 15 percent of their normal capacity. At this stage, kidneys cannot effectively remove waste or excess fluid from the blood system, and dialysis or a kidney transplant is necessary to live.

14 Jul 2015

Postmenopausal women with kidney, bladder stones not at increased risk for osteoporosis

Postmenopausal women with kidney or bladder stones are not at increased risk for osteoporosis, but they do have about a 15 percent increased risk of another painful stone, physician-scientists report.

14 Jul 2015

University of Leeds scientists uncover genes implicated in common inherited diseases

Scientists from the University of Leeds have uncovered the most comprehensive list yet of genes implicated in a group of common inherited diseases.

14 Jul 2015

New surgical method preserves long-term renal function following removal of renal tumours

Renal cell carcinomas are one of the most common types of cancer. In order to preserve its wide range of functions, every effort is made not to remove the entire kidney, but rather just a portion of it. A surgical method that preserves long-term renal function has now been carried out successfully for the first time in the Department of Urology at the MedUni Vienna and Vienna General Hospital.

13 Jul 2015

Envarsus XR receives FDA approval for treatment of kidney transplant recipients

Veloxis Pharmaceuticals A/S today announced U.S. Food and Drug Administration approval of Envarsus XR (tacrolimus extended-release tablets) for the prophylaxis of rejection in kidney transplant patients who require or desire conversion from other twice-daily tacrolimus products to once-daily Envarsus XR.

11 Jul 2015

Nephrology News and Research

Further Reading

Omeros' OMS721 granted FDA Fast Track designation for treatment of atypical hemolytic uremic syndrome

UC San Diego researchers identify pivotal player in diabetic kidney disease

Mercy Medical Center named third best hospital in Maryland

Tyrone Regional Health Network signs letter of intent to become member of Penn State Health

Research suggests that only one in three older Americans have diabetes under control

Study examines link between use of diabetes drug pioglitazone and increased risk of bladder cancer

UCLA Health's hospitals named among nation's best in U.S. News and World Report

Dietary phosphate appears to cause spikes in blood phosphorus levels

Tamsulosin works better on large kidney stones

Researchers use iPSCs to explore new treatments for kidney disease

UC San Diego Health ranked again among nation's best hospitals by U.S. News & World Report

MU researcher receives $2.2 million grant to develop system to display clear blood pressure information

New approach holds great promise for developing effective treatments for human mitochondrial diseases

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Johns Hopkins endocrinologists propose new protocol for inpatient glucose management

Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients

Postmenopausal women with kidney, bladder stones not at increased risk for osteoporosis

University of Leeds scientists uncover genes implicated in common inherited diseases

New surgical method preserves long-term renal function following removal of renal tumours

Envarsus XR receives FDA approval for treatment of kidney transplant recipients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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