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Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children's Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence.

27 Apr 2022

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen in health care settings.

27 Apr 2022

Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

Researchers assessed the epigenetic aging in COVID-19 patients and its impact on COVID-19 severity by a genome-wide deoxyribonucleic acid methylation profiling analysis.

27 Apr 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

Understanding the Choice Between Individual Versus Social Housing Mice and Its Impact On Research

In this interview, Steffen van Heijningen discusses the differences between individual and social housing of mice and how housing conditions can impact the research.

From Noldus Information Technology 26 Apr 2022

Scientists show how T cells may help protect against severe COVID

In a recent study published in the Clinical Infectious Diseases journal, the researchers summarized the perspectives and observations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related adaptive immunity.

25 Apr 2022

Researchers develop new platform capable of mitochondrial DNA editing

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

A new study discussed the role of complement factor H-related protein 5 (CFHR5) in venous thromboembolism (VTE) patients and hospitalized COVID-19 patients.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Researchers identify five types of bacteria in men with aggressive prostate cancer

Researchers at the University of East Anglia have found a link between bacteria and aggressive forms of prostate cancer.

25 Apr 2022

Species differences in somatic mutations shed light on aging

A recent study published in the journal Nature aimed to elucidate, through a comparative analysis, the diversity in mutagenesis across different species, and the long-established hypothesis regarding evolution in the rates of somatic mutation, as well as their role in cancer and aging.

25 Apr 2022

Impact of COVID-19 vaccination on anti-nucleocapsid antibody levels

Anti-N antibodies may have lower sensitivity in mRNA-1273-vaccinated individuals who were previously infected with SARS-CoV-2.

24 Apr 2022

C. difficile study finds the sharing of multiple antibiotic-resistance genes between pigs and humans

A study investigating samples of the superbug Clostridioides difficile across 14 pig farms in Denmark finds the sharing of multiple antibiotic-resistance genes between pigs and human patients, providing evidence that that animal to human (zoonotic) transmission is possible.

24 Apr 2022

Genome News and Research

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

Novel plug-and-play multi-organ chip can be customized to the patient

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Genetic cause of lupus identified

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Understanding the Choice Between Individual Versus Social Housing Mice and Its Impact On Research

Scientists show how T cells may help protect against severe COVID

Researchers develop new platform capable of mitochondrial DNA editing

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

The challenges of Omicron

Researchers identify five types of bacteria in men with aggressive prostate cancer

Species differences in somatic mutations shed light on aging

Impact of COVID-19 vaccination on anti-nucleocapsid antibody levels

C. difficile study finds the sharing of multiple antibiotic-resistance genes between pigs and humans

Metabolomics and multi-omics perspective of cancer show promise for finding new treatments

Incidence of venous thromboembolism following COVID-19 vaccination

Continual genomic surveillance in Africa provides insights into evolving SARS-CoV-2 pandemic

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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