Preclinical News and Research

RSS

Compounds derived from common hop plant thwart cancer cells

The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.

3 Apr 2019

Analysis of tumor microenvironment to improve effectiveness of preclinical trials

It was shown that co-culturing HeLa adenocarcinoma cells, peripheral blood mononuclear cells, and mesenchymal stromal cells results in changes in the proliferative activity of the peripheral blood mononuclear cells and mesenchymal stromal cell populations.

3 Apr 2019

UC San Diego Health treats first cancer patient with iPSC-derived cell therapy

After 10 years in remission, Derek Ruff's cancer returned, this time as stage IV colon cancer. Despite aggressive rounds of chemotherapy, palliative radiotherapy and immunotherapy, his disease progressed.

2 Apr 2019

Researchers explore biological mechanisms behind obesity-cancer link

New studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers explore biological mechanisms behind obesity and its link with cancer.

1 Apr 2019

Household dust may be contributing to childhood obesity epidemic

New research has found that chemicals found in household dust may promote fat cell development and contribute to increased weight gain in children.

1 Apr 2019

Scientists create new models of tropical eye worm for development of anti-filarial drugs

Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis.

30 Mar 2019

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

While non-small cell lung cancer is the more common form of lung cancer and attracts the lion's share of the research funding, recent developments in small cell lung cancer may be shifting that slightly.

29 Mar 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success.

28 Mar 2019

Enamine and Lundbeck announce expansion of drug discovery collaboration

Enamine and H. Lundbeck today announced the expansion of their research collaboration.

From Enamine Ltd 26 Mar 2019

MILabs installs pre-clinical Adaptive microCT scanner at Jagiellonian University in Poland

Jagiellonian University in Kraków recently became the first institute in Poland to install MILabs’ Adaptive U-CT for in-vivo preclinical imaging.

25 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

New study offers insight into development of delusions

Delusions are one of the most common symptoms of psychosis, but little is known about what causes them. A new study from researchers at Columbia University and New York State Psychiatric Institute offers insight into the development of delusions, which could lead to better treatments for people with psychosis.

22 Mar 2019

Major scientific study of wound care dressings wins 'Best Clinical or Preclinical Research Award'

UNIVERSITY of Huddersfield researchers have taken part in an award-winning project that will enable healthcare companies to develop and supply more effective wound dressings.

20 Mar 2019

Cholesterol lowering drug can also help treat cancer-associated cachexia

Brazilian researchers have discovered that a drug regularly prescribed to control cholesterol can also be used to treat cachexia, or wasting syndrome, a condition characterized by rapid weight loss and muscle atrophy associated with extreme physical weakness.

19 Mar 2019

Researchers identify origin of chronic pain in humans

A new study by researchers at The University of Texas at Dallas, UT MD Anderson Cancer Center, UT Health Science Center at Houston and Baylor College of Medicine has produced evidence of the source of chronic pain in humans, revealing several new targets for pain treatment.

19 Mar 2019

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

The Global Antibiotic Research and Development Partnership and Evotec AG are today announcing the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance.

19 Mar 2019

Low levels of certain eye proteins could serve as predictor for Alzheimer’s

Researchers at Boston Medical Center have found that low eye-fluid levels of two proteins associated with Alzheimer’s could serve as a potential predictor of the disease.

19 Mar 2019

Bruker showcases new analytical systems and applied market solutions at Pittcon 2019

At Pittcon 2019, Bruker this week highlights new and innovative analytical systems and high-value applied market solutions for food analysis, pharma applications, materials science research and quality control, clinical and preclinical research, and advances in scientific software solutions.

From Bruker 19 Mar 2019

GARP protein can be a potential target for immunotherapy against colorectal cancer

Colorectal cancer is the third leading cause of cancer-related deaths in both men and women. Despite significant advances in therapies for this particular cancer, the five-year survival rate is 12 percent, according to the American Cancer Society.

19 Mar 2019

Preclinical News and Research

Compounds derived from common hop plant thwart cancer cells

Analysis of tumor microenvironment to improve effectiveness of preclinical trials

UC San Diego Health treats first cancer patient with iPSC-derived cell therapy

Researchers explore biological mechanisms behind obesity-cancer link

Household dust may be contributing to childhood obesity epidemic

Scientists create new models of tropical eye worm for development of anti-filarial drugs

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

Enamine and Lundbeck announce expansion of drug discovery collaboration

MILabs installs pre-clinical Adaptive microCT scanner at Jagiellonian University in Poland

City of Hope exhibits current studies and data on cancer therapies at AACR

New study offers insight into development of delusions

Major scientific study of wound care dressings wins 'Best Clinical or Preclinical Research Award'

Cholesterol lowering drug can also help treat cancer-associated cachexia

Researchers identify origin of chronic pain in humans

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

Low levels of certain eye proteins could serve as predictor for Alzheimer’s

Bruker showcases new analytical systems and applied market solutions at Pittcon 2019

GARP protein can be a potential target for immunotherapy against colorectal cancer

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

Latest eBooks

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics