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Reproductive justice principles improve perinatal mental health for Black birthing patients

Perinatal interventions guided by reproductive justice principles can have positive effects on the perinatal mental health of Black birthing patients and, perhaps, the mental health development of their infants, states a systematic review published in a special issue of Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer.

10 Mar 2025

Breakthrough drug combination targets KRAS mutation in lung cancer

A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib-an FDA-approved drug in the market-and an experimental drug called FGTI-2734, which could make precision medicine more effective for patients with a highly resistant form of lung cancer.

10 Mar 2025

New supercharged CAR-T cell therapy shows promise against resistant cancers

Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against cancer cells that are harder for prior CAR-T therapies to detect and fight.

10 Mar 2025

Many individuals with Niemann-Pick disease lack neutralizing antibodies against AAV2 or AAV9

A new study in the peer-reviewed journal Human Gene Therapy showed that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9.

10 Mar 2025

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

10 Mar 2025

Restoring gut health in ulcerative colitis through microbiome-based therapy

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health.

10 Mar 2025

Reprogramming T cells to overcome tumor challenges

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability to boost the immune system's fight against cancer, showing promise for improving patient outcomes in difficult-to-treat malignancies.

10 Mar 2025

New insights into dental problems in hypophosphatasia patients

Hypophosphatasia is a relatively common skeletal disease that primarily affects bone and tooth strength. In the third national dental survey of hypophosphatasia in Japan, recently published in Scientific Reports, researchers analyzed the dental issues faced by Japanese patients in their largest survey to date.

10 Mar 2025

Can microbiome discoveries finally become treatments? Scientists show the way

Researchers propose a novel iterative strategy combining big data and experimental models to move microbiome research from theory to clinical applications. The study highlights the need to bridge the gap between correlation and causation to develop effective microbiome-based therapies.

9 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Circular RNA plays key role in cancer biology and therapy

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

8 Mar 2025

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Thurman M. Wheeler, MD, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in Nature Communications, "Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1."

8 Mar 2025

EZH2 inhibition offers hope for fighting treatment-resistant cancers

The critical role of EZH2, an essential epigenetic regulator, in cancer progression and treatment is underscored in this new review article published in Genes & Diseases.

8 Mar 2025

Existing drug could prevent liver damage caused by ammonia build-up

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice led by researchers from UCL.

7 Mar 2025

Insilico Medicine's AI-driven drug Rentosertib receives official generic name

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, recently announced that its breakthrough drug candidate for idiopathic pulmonary fibrosis (IPF) – Rentosertib (formerly known as ISM001-055) – has been granted an official generic name by the United States Adopted Names (USAN) Council.

7 Mar 2025

Music-based therapy may benefit people living with dementia

A new Cochrane review has found evidence that music-based therapy may benefit people living with dementia, particularly by improving symptoms of depression.

7 Mar 2025

New clinical study published: Astaxanthin reduces digital eye strain in children

A new study shows that astaxanthin supplementation can improve both acute and chronic digital eye strain in children.

7 Mar 2025

Novel treatment approach shows promise for advanced HPV-negative head and neck cancer

Researchers from the University of Chicago Medicine Comprehensive Cancer Center demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC).

7 Mar 2025

Partial gland cryoablation offers long-term success for prostate cancer patients

A five-year study on men that had just the cancerous portion of their prostate glands destroyed shows that the procedure averted cancer recurrence in most patients while preserving urinary and sexual function.

6 Mar 2025

Long-acting HIV injections show success in patients with struggles to take daily pills

UCSF researchers are the first to demonstrate that the approach works for the patients who need it the most.

6 Mar 2025

Therapy News and Research

Reproductive justice principles improve perinatal mental health for Black birthing patients

Breakthrough drug combination targets KRAS mutation in lung cancer

New supercharged CAR-T cell therapy shows promise against resistant cancers

Many individuals with Niemann-Pick disease lack neutralizing antibodies against AAV2 or AAV9

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Restoring gut health in ulcerative colitis through microbiome-based therapy

Reprogramming T cells to overcome tumor challenges

New insights into dental problems in hypophosphatasia patients

Can microbiome discoveries finally become treatments? Scientists show the way

Understanding the role of LSD1 in cellular processes and disease

Circular RNA plays key role in cancer biology and therapy

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

EZH2 inhibition offers hope for fighting treatment-resistant cancers

Existing drug could prevent liver damage caused by ammonia build-up

Insilico Medicine's AI-driven drug Rentosertib receives official generic name

Music-based therapy may benefit people living with dementia

New clinical study published: Astaxanthin reduces digital eye strain in children

Novel treatment approach shows promise for advanced HPV-negative head and neck cancer

Partial gland cryoablation offers long-term success for prostate cancer patients

Long-acting HIV injections show success in patients with struggles to take daily pills

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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