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Machine learning model accurately classifies the stages of bladder cancer

The invasive and expensive diagnosis process of bladder cancer, which is one of the most common and aggressive cancers in the United States, may be soon helped by a novel non-invasive diagnostic method thanks to advances in machine learning research at the San Diego Supercomputer Center, Moores Cancer Center, and CureMatch Incorporated.

3 Jul 2019

Risk of stillbirth increases by continuing pregnancy to 41 weeks' gestation

With every week that a pregnancy continues past term, the risk of stillbirth increases, according to an analysis of more than 15 million pregnancies led by Queen Mary University of London.

3 Jul 2019

IU-connected startup working to enable precision medicine for mental health issues, chronic pain

A new startup company founded on science developed at Indiana University is working to enable precision medicine by commercializing the first objective tests for mental health issues, including suicide risk, post-traumatic stress disorder and depression, and for pain, all of which historically have been difficult to measure for patients and health care providers alike.

2 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Study: Antidepressants reduce mortality by 35% in patients with diabetes

Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

2 Jul 2019

New statement lays down recommendations to combat fall in vaccination rates

Search engines and social media organizations must do more to prevent the spread of inaccurate information on childhood vaccination, and governments must better support mandatory immunization programs, says an international group of leading public health scientists in a statement published in the Journal of Health Communication.

2 Jul 2019

Pesticide exposure may increase risk of depression in adolescents

Adolescents exposed to elevated levels of pesticides are at an increased risk of depression, according to a new study led by Jose R. Suarez-Lopez, MD, PhD, assistant professor in the Department of Family Medicine and Public Health at University of California San Diego School of Medicine.

2 Jul 2019

Study highlights need to consider patient's weight before prescribing new cancer drugs

A new class of cancer drugs just now entering the marketplace seems promising so far, but researchers at the University of Illinois at Chicago urge doctors to take into account a patient's weight and liver status before prescribing them once they come on the market.

2 Jul 2019

$Hypofractionated proton therapy for prostate cancer can be just as effective as standard treatment$

Hypofractionated proton therapy for prostate cancer can be just as effective as standard treatment

Treating prostate cancer with higher doses of proton therapy over a shorter amount of time leads to similar outcomes when compared to standard dose levels and treatments and is safe for patients, according to a new study examining the risk of long-term side-effects from the treatment.

2 Jul 2019

Gene mutations may not always predict cardiomyopathy

More than 750,000 people in the United States have dilated cardiomyopathy, a potentially life-threatening condition in which the heart's main pumping chamber, the left ventricle, enlarges and grows increasingly weak.

2 Jul 2019

Columbia study aims to understand barriers to inclusion of ethnic minorities in genetic research

Precision medicine represents a revolution in health care. Doctors and researchers may soon be able to use the genetic profiles of patients to predict with great accuracy which treatment and prevention protocols will work for them.

2 Jul 2019

Supervised fun, exercise both improve psychosocial health of children with obesity

A program with clear rules, routines and activities, attentive adults and a chance to interact with peers appears to work as well at improving the quality of life, mood and self-worth of a child who is overweight or obese as a regular exercise program, researchers report.

2 Jul 2019

'Scissors' component of CRISPR/Cas9 sometimes gets stuck

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.

2 Jul 2019

3D breast tumor models may improve drug discovery and testing

Dr. Hossein Tavana, an associate professor of biomedical engineering at The University of Akron, has received a grant of $1.13 million from the prestigious National Cancer Institute to further develop 3D tumor models of triple-negative breast cancer -- which may improve drug testing and lead to the discovery of new, more effective anticancer drugs.

2 Jul 2019

Study reveals time taken for DNA repair after chemotherapy

In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.

2 Jul 2019

Discovery by NETRF-funded researchers may help predict recurrence of pNETs

ARX and PDX1 levels can be measured using immunohistochemistry, a test that stains tumor tissue and is routine in clinical laboratories.

2 Jul 2019

Gene mutation discovery leads to novel treatment for patient with severe lymphatic condition

Faced with a preteen boy in pain and struggling to breathe from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and harnessed that knowledge to develop a novel treatment that dramatically improved the problem.

2 Jul 2019