Clinical Trial News and Research

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New drug could be a game changer for cancer patients undergoing chemotherapy

Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects – especially kidney toxicity, that can lead to acute kidney failure.

15 Nov 2022

Lipid screening and dyslipidemia intervention in adolescence may stop atherosclerosis progression

Consistently elevated lipids and dyslipidemia in early life were associated with worsening subclinical atherosclerosis, but simulated lipid treatment in late adolescence stopped atherosclerosis progression, a paper published in Atherosclerosis concludes.

15 Nov 2022

Three-year MRC funded project to develop new drugs for treating childhood epilepsy

Scientists at Aston University have started work on a project that will look for new drug treatments to prevent the onset of childhood epilepsy.

15 Nov 2022

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

During the conference, we caught up with some of the speakers to learn more about their work, what they were presenting, and their thoughts about the future of Oncology and Precision Medicine.

15 Nov 2022

PALS program effective in ensuring diverse representation in lupus clinical trials

The Lupus Research Alliance and its affiliate Lupus Therapeutics presented data at ACR Convergence 2022 with results showing the effectiveness of a pilot peer education program called the Patient Advocates for Lupus Studies (PALS), in increasing knowledge, perception, and willingness among people with Systemic Lupus Erythematosus (SLE) to participate in clinical trials.

14 Nov 2022

New online tool launched to increase awareness and participation in Alzheimer’s clinical trials

Also at AAIC 2021, the National Institute on Aging (NIA), part of the U.S. National Institutes of Health, launched a new online tool, Outreach Pro, to help researchers and clinicians increase awareness and participation in clinical trials on Alzheimer's disease and other dementias, especially among traditionally underrepresented communities.

14 Nov 2022

Unique clinical trial in pet dogs could unlock treatment breakthrough for childhood cancers

Telethon Kids Institute is leading a unique clinical trial in pet dogs that could pave the way for a new immunotherapy treatment for one of the most common childhood cancers, Sarcoma.

14 Nov 2022

Oral deucravacitinib shows promise in patients with active lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus.

14 Nov 2022

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Type I interferon (IFN) is a powerful immune activator that is present at high levels in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the first placebo-controlled long-term trial of anifrolumab - a human monoclonal antibody that targets the type I IFN receptor - in patients with lupus.

14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

World Diabetes Day 2022: The Importance of Type 1 Research and Awareness with JDRF

For World Diabetes Day 2022, News-Medical speaks to JDRF, the type 1 diabetes charity, about the importance of type 1 diabetes research and awareness, as well as dispelling the misconceptions behind this autoimmune condition.

14 Nov 2022

Reversing paralysis with electrical stimulation of neurons

In a recent study published in the Nature journal, researchers assessed the impact of spatiotemporal epidural electrical stimulation (EES) on individuals suffering from chronic spinal cord damage.

13 Nov 2022

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Results from a recent clinical trial published by Wiley in Arthritis & Rheumatology demonstrate that patients with knee osteoarthritis experience short term pain relief from genicular nerve blocks - or locally injected anesthetics that block nerves around the knee joint.

13 Nov 2022

Updated EULAR recommendations on the use of DMARDs for people with RA

Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with RA have become a most important publication in the field, and their updates are relied upon by many healthcare professionals, professional organizations and other stakeholders to offer an up-to-date and robust analysis on an optimal approach to the application of available treatment options in clinical practice.

11 Nov 2022

Study finds no differences in CAR T-cell therapy outcomes among pediatric ALL patients across different socioeconomic levels

Social determinants of health affect the outcomes of many illnesses, and pediatric cancer is no exception. In fact, children with acute lymphoblastic leukemia (ALL) living in poverty are significantly more likely to relapse and die from their disease than those from wealthier backgrounds.

11 Nov 2022

Focused ultrasound treatment offers long-term relief for patients with essential tremor

A scalpel-free, high-tech form of brain surgery pioneered at UVA Health offers long-term relief for patients with essential tremor, a common movement disorder, a five-year review shows.

10 Nov 2022

New approach can help design shorter, more powerful trials to assess Parkinson’s drugs

Testing whether a new drug impacts the progression of Parkinson's disease takes years, in part because the disease often advances so slowly.

10 Nov 2022

$3.2 million grant helps to study the benefits of mind-body practices for patients undergoing surgery

Can mind-body practices such as gentle yoga or self-reflection benefit patients undergoing surgery? It's a question that researchers at Wake Forest University School of Medicine are examining with the support of a five-year, $3.2 million grant from the National Cancer Institute

10 Nov 2022

Treatment using CRISPR genome editing alleviates swelling attacks in hereditary angioedema patients

Hereditary angioedema (HAE) is a rare, genetic disorder characterized by severe, recurring, and unpredictable swelling attacks in various organs and tissues of the body, which can be painful, debilitating, and life-threatening.

10 Nov 2022

Enzyme that drives growth of medulloblastoma may hold the key to future treatment

An enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster University-led study.

10 Nov 2022

Clinical Trial News and Research

New drug could be a game changer for cancer patients undergoing chemotherapy

Lipid screening and dyslipidemia intervention in adolescence may stop atherosclerosis progression

Three-year MRC funded project to develop new drugs for treating childhood epilepsy

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

PALS program effective in ensuring diverse representation in lupus clinical trials

New online tool launched to increase awareness and participation in Alzheimer’s clinical trials

Unique clinical trial in pet dogs could unlock treatment breakthrough for childhood cancers

Oral deucravacitinib shows promise in patients with active lupus

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

World Diabetes Day 2022: The Importance of Type 1 Research and Awareness with JDRF

Reversing paralysis with electrical stimulation of neurons

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Updated EULAR recommendations on the use of DMARDs for people with RA

Study finds no differences in CAR T-cell therapy outcomes among pediatric ALL patients across different socioeconomic levels

Focused ultrasound treatment offers long-term relief for patients with essential tremor

New approach can help design shorter, more powerful trials to assess Parkinson’s drugs

$3.2 million grant helps to study the benefits of mind-body practices for patients undergoing surgery

Treatment using CRISPR genome editing alleviates swelling attacks in hereditary angioedema patients

Enzyme that drives growth of medulloblastoma may hold the key to future treatment

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