Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Inhaling salt mist helps cystic fibrosis patients

Two studies published in the New England Journal of Medicine have found that inhaling mists of salt water can help clear mucus and improve lung function for cycstic fibrosis sufferers.

25 Jan 2006

First-of-its-kind study in heart attack patients seeks to prevent heart failure with stem cells

University of Rochester Medical Center researchers have announced the launch of a study that will examine whether transplanted stem cells can be safely used to treat damaged heart muscle in patients just after their first heart attack.

23 Jan 2006

Salt water treatment for cystic fibrosis both effective and cheap

Two teams of scientists working half a world apart, have identified what they believe is a simple, effective and inexpensive treatment to reduce lung problems associated with cystic fibrosis.

19 Jan 2006

Limitless applications for nitric oxide in healthcare, bio-security, agriculture and industrial applications

Low levels of nitric oxide gas can prevent and kill disease-causing bacteria by tricking them into thinking their time is up, according to scientists from the Environmental Biotechnology Cooperative Research Centre (EBCRC) and the University of New South Wales.

10 Jan 2006

UCLA examines disease-versus-disease interactions

The knowledge that one disease may prevent the onset of another is not new. For example, the discovery that cowpox vaccines can prevent smallpox dates back to 1798.

5 Jan 2006

Reduced rates of lung function decline in cystic fibrosis clinical study patients

Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.

2 Jan 2006

University at Buffalo researches rules for targeting RNA

Once described as DNA's less-famous chemical cousin, RNA, or ribonucleic acid, recently has moved to center stage.

15 Dec 2005

Liver transplants may not be suitable for all cystic fibrosis patients

A new study on patients with cystic fibrosis (CF) who have had abnormal bleeding from ruptured blood vessels in the esophagus (variceal hemorrhage) as a result of liver disease found that transplant may not be indicated if there are no other indications of advanced liver disease.

5 Dec 2005

Drinking lots of coffee and tea can reduce the risk of chronic liver disease

A study published in the American Gastroenterological Association (AGA) journal Gastroenterology found that people at high risk for liver injury may be able to reduce their risk for developing chronic liver disease significantly by drinking more than two cups of coffee or tea daily.

2 Dec 2005

Fullerenes can help fend off damage to normal tissue from radiation

Using transparent zebrafish embryos, researchers at Jefferson Medical College have shown that a microscopic nanoparticle can help fend off damage to normal tissue from radiation.

28 Nov 2005

Sperm stem cells research provides exciting findings

New experiments that prevented rat sperm stem cells from changing permanently into sperm have brought researchers one step closer to coaxing such cells to behave like embryonic stem cells, capable of growing into many other types of cells in the body.

20 Nov 2005

Largest hepatitis-C U.S. study defines optimal therapy

Final results of the WIN-R trial,[1] the largest hepatitis C study conducted in U.S. patients, showed that weight-based REBETOL (ribavirin, USP) in combination therapy with PEG-INTRON (peginterferon alfa-2b) achieved significantly higher rates of sustained virologic response (SVR)[2] and lower rates of relapse compared to the combination therapy using a flat dose of ribavirin.

14 Nov 2005

MRI measurements of scar tissue accurately predict the risk of arrhythmia-related sudden death

Using magnetic resonance imaging (MRI) scans of the heart wall, researchers at Johns Hopkins have found that people whose muscle wall thickness contained more than 25 percent scar tissue were approximately nine times more likely to test positive for a fast and dangerous heart rhythm known as ventricular arrhythmia.

3 Nov 2005

Paclitaxel may help treat scleroderma

Using a novel model for scleroderma, researchers from Duke University Medical Center have discovered two important insights into this devastating disorder - the anti-cancer drug paclitaxel (Taxol) may prevent the skin thickening and small blood vessel destruction that characterizes the disease.

1 Nov 2005

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

25 Oct 2005

Study shows cystic fibrosis gene mutation a risk factor for young-onset pancreatic cancer disease

Mayo Clinic researchers have found the risk of developing pancreatic cancer at a young age (under 60) to be twice as high for people who carry a mutation of the gene that causes cystic fibrosis, compared to noncarriers. Results of a pilot and follow-up study were reported Oct. 14, 2005, online in the journal Gut.

23 Oct 2005

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

By using a chemical analysis method developed for air-pollution testing, UCI chemists and pediatricians have found that people with cystic fibrosis exhale higher concentrations of sulfur compounds from their lungs than do people who don't have the disease.

17 Oct 2005

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

A new study from the University of North Carolina at Chapel Hill School of Medicine may have found a way to identify those at greatest risk, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ. The new findings appear in the October issue of the journal Liver Transplantation.

9 Oct 2005

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have developed a new way to predict the ability of certain small molecules to protect proteins in the cells of a wide variety of organisms living in extreme environments.

9 Oct 2005

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Two New Jersey research teams are reporting discoveries about the biological nature of psychiatric disorders that may bring them closer to the ultimate goal of finding cures for complex diseases, such as autism and schizophrenia.

9 Oct 2005

Fibrosis News and Research

Further Reading

Inhaling salt mist helps cystic fibrosis patients

First-of-its-kind study in heart attack patients seeks to prevent heart failure with stem cells

Salt water treatment for cystic fibrosis both effective and cheap

Limitless applications for nitric oxide in healthcare, bio-security, agriculture and industrial applications

UCLA examines disease-versus-disease interactions

Reduced rates of lung function decline in cystic fibrosis clinical study patients

University at Buffalo researches rules for targeting RNA

Liver transplants may not be suitable for all cystic fibrosis patients

Drinking lots of coffee and tea can reduce the risk of chronic liver disease

Fullerenes can help fend off damage to normal tissue from radiation

Sperm stem cells research provides exciting findings

Largest hepatitis-C U.S. study defines optimal therapy

MRI measurements of scar tissue accurately predict the risk of arrhythmia-related sudden death

Paclitaxel may help treat scleroderma

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

Study shows cystic fibrosis gene mutation a risk factor for young-onset pancreatic cancer disease

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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