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New mouse model grants insight into the genetic and molecular mechanisms underpinning acute myeloid leukemia

Leukaemia - cancer of blood or bone marrow is caused by mutations that allow defective blood cells to accumulate and displace healthy blood.

8 Apr 2008

Rare genetic syndrome may hold key to cure for heat stroke

A genetic disorder that can cause a fatal rise in body temperature in some patients undergoing general anesthesia may hold the key to a cure for heat stroke, according to research published in the April 4 edition of the journal Cell.

4 Apr 2008

Key factor in brain development revealed, offers insight into lissencephaly

In the earliest days of brain development, the brain's first cells - neuroepithelial stem cells - divide continuously, producing a population of cells that eventually evolves into the various cells of the fully formed brain.

28 Mar 2008

Lithium chloride slows development of inclusion body myositis

A new UC Irvine study finds that lithium chloride, a drug used to treat bipolar disorder, can slow the development of inclusion body myositis, a skeletal muscle disease that affects the elderly.

19 Mar 2008

Silencing gene in tobacco plants reduces harmful carcinogens

In large-scale field trials, scientists from North Carolina State University have shown that silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves.

19 Mar 2008

On the trail of rogue genetically modified pathogens

Bacteria can be used to engineer genetic modifications, thereby providing scientists with a tool to combat many challenges in areas from food production to drug discovery.

18 Mar 2008

Penn researchers identify first sex chromosome gene involved in meiosis and male infertility

A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity.

17 Mar 2008

MicroRNAs help zebrafish regenerate fins

Biologists have discovered a molecular circuit breaker that controls a zebrafish's remarkable ability to regrow missing fins, according to a new study from Duke University Medical Center.

17 Mar 2008

Finding in mice could help prevent common complications of kidney damage

Kidney damage often sets off a slew of complications in patients, spreading organ failure like wildfire throughout their bodies.

14 Mar 2008

New mouse model of bipolar disorder

Bipolar Disorder (BPD or manic-depressive illness) is one of the most serious of all mental disorders, affecting millions of individuals worldwide.

13 Mar 2008

Novel brain cancer drug HhAntag for children may damage bones

A novel drug that fully eliminated brain tumors from mice in a dramatic 2004 study has shown a darker side - causing permanent bone damage in younger mice.

11 Mar 2008

Paradoxical Alzheimer's finding may provide better understanding of memory loss

Do you remember the seventh song that played on your radio on the way to work yesterday?

10 Mar 2008

Improved method for genetically manipulating human embryonic stem cells

UC Irvine researchers have discovered a dramatically improved method for genetically manipulating human embryonic stem cells, making it easier for scientists to study and potentially treat thousands of disorders ranging from Huntington's disease to muscular dystrophy and diabetes.

10 Mar 2008

Watery pools in bone marrow key to psoriatic arthritic damage

Researchers have learned more about how a leading drug prevents certain types of arthritis from eating away at bone, according to a study published in the March edition of the Annals of the Rheumatic Diseases.

4 Mar 2008

New advances in miRNA

miRNA research is now one of the most interesting areas in the life science world, reports Genetic Engineering and Biotechnology News (GEN).

From Thermo Fisher Scientific Inc. 3 Mar 2008

New discovery on programmed cell death

Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.

1 Mar 2008

Brain stress system shows promise as a new therapeutic target for alcoholism

A brain circuit that underlies feelings of stress and anxiety shows promise as a new therapeutic target for alcoholism, according to new studies by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).

27 Feb 2008