Cell Metabolism News and Research

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Targeting one's internal clock could prevent or slow breast cancer progression

City of Hope scientists have identified an unlikely way to potentially prevent or slow the progression of aggressive breast cancer: target one's internal clock.

13 Feb 2020

Novel drug combination discovered to induce high rates of human beta cell proliferation

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells- the cells in the pancreas that produce insulin- without harming most other cells in the body.

12 Feb 2020

New noninvasive way to monitor the health of brain cells using an infrared laser

With no way to reliably tell whether an athlete has a concussion, many may be playing with an undiagnosed injury. Likewise, 2 million people die every year because we don't have an early warning when brain cells are dying--and another 4 million experience cognitive disabilities.

3 Feb 2020

Turning stink into therapy for atherosclerosis

In an amusing but amazing turnaround, it seems the most foul-smelling compound on earth, called putrescine, could help relieve chronic inflammation, most importantly in the arterial thickening called atherosclerosis. This discovery is reported in the journal Cell Metabolism in January 2020.

30 Jan 2020

New uses for old medicines

It turns out that in the rush to invent new drugs to treat cancers, scientists may have overlooked some obvious possibilities of existing drugs currently being used for other diseases. A new study says that therapies for diabetes, inflammation and alcoholism, and even for dog arthritis, can also result in the successful killing of cancer cells in culture.

20 Jan 2020

CALCR neurons may influence long-term control of food intake and body weight

Ever eaten something, gotten sick and then didn't want to eat that food again because of how it made you feel? That's because a signal from the gut to the brain produced that sickness, creating a taste aversion.

17 Jan 2020

Leukemic cells are addicted to vitamin B6, research shows

Scientists have discovered that Acute Myeloid Leukemia (AML) grows by taking advantage of the B6 vitamin to accelerate cell division.

13 Jan 2020

Researchers identify new prevention strategy for type 1 diabetes

A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by scientists at the U.S. Department of Energy's Pacific Northwest National Laboratory and Indiana University School of Medicine.

9 Jan 2020

Fat over-spills from the liver into the pancreas trigger Type 2 diabetes

For the first time, scientists have been able to observe people developing Type 2 diabetes - and confirmed that fat over-spills from the liver into the pancreas, triggering the chronic condition.

22 Dec 2019

Glutamine could help obese people reduce inflammation of fat tissue

Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types.

19 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Study shows how immune cells quickly switch to attack mode

Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down the pathogens instead.

17 Dec 2019

NIH-funded research finds differences in energy use by immune T cells in ME/CFS

New findings published in the Journal of Clinical Investigation suggest that specific immune T cells from people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce energy.

12 Dec 2019

Time-restricted eating can help treat metabolic syndrome

Metabolic syndrome affects nearly 30 percent of the U.S. population, and increases the risk for type 2 diabetes, heart disease and stroke. But lifestyle interventions such as adopting a healthy diet and increasing physical exercise are difficult to maintain and, even when combined with medication, are often insufficient to fully manage the disease.

5 Dec 2019

Study reveals role of corpora amylacea in expelling brain waste substances

An article published in Proceedings of the National Academy of Sciences describes a new pathway in the central nervous system to expel waste substances from the brain through the creation of corpora amylacea, aggregates formed by glucose polymers amassing waste products.

4 Dec 2019

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Fueling exploration by investigators who collaborate under a research consortium partnership as recognized by the National Cancer Institute, between Rutgers Cancer Institute of New Jersey and Princeton University, the GO2 Foundation for Lung Cancer has awarded $250,000 toward the identification and development of novel strategies to address treatment resistance in non-small cell lung cancer.

3 Dec 2019