Chromosome 8 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 8, one copy inherited from each parent, form one of the pairs. Chromosome 8 spans about 146 million DNA building blocks (base pairs) and represents between 4.5 percent and 5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 8 likely contains between 700 and 1,100 genes.

Genes on chromosome 8 are among the estimated 20,000 to 25,000 total genes in the human genome.

Using convolutional neural network to automate the identification of chromatid cohesion defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion.

13 Mar 2023

Scientists identify the cause of leukemia in people with trisomy 21

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

10 Mar 2023

Study unveils a key factor involved in the DNA damage response and repair

A research team, affiliated with UNIST has unveiled a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair.

8 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

Researchers analyzed polygenic risk scores in whole genome sequences obtained from blood samples of long COVID patients to determine genomic predictors of long COVID.

2 Mar 2023

PARK2 duplication or microdeletion and neurological diseases

In a recent study published in the Genes journal, researchers assessed the impact of PARK2 duplication or microdeletion on neurological diseases such as Parkinson's.

28 Feb 2023

Genome editing techniques based on bacterial-artificial-chromosome in herpesvirus research

In a recent study published in the Microorganisms journal, researchers in China reviewed the uses of bacterial-artificial-chromosome (BAC)-based genome editing techniques in herpesvirus research.

28 Feb 2023

Brain over-activation could be causing seizures and social deficits in genetic subtype of autism

Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.

28 Feb 2023

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

The Tecan Group and Oxford Nanopore Technologies plc (Oxford Nanopore) today announce their collaboration to drive easier high-throughput nanopore library preparation in an automated, hands-free fashion.

From Tecan 27 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

10 Feb 2023

3D architecture ofAedes aegypti’s chromosomes may offer clues on gene expression, regulation

When it comes to DNA, one pesky mosquito turns out to be a rebel among species.

9 Feb 2023

New blood test can detect prostate cancer with greater accuracy than current methods

Researchers at the University of East Anglia have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods.

8 Feb 2023

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.

2 Feb 2023

Study identifies the DNA roots of resistance to targeted cancer therapy

A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

25 Jan 2023

Study provides an estimate of people in the United States with VEXAS syndrome

About 13,200 men and another 2,300 women in the United States over age 50 are estimated to have VEXAS syndrome, according to a new study led by researchers at NYU Grossman School of Medicine.

24 Jan 2023

Green tea may protect against telomere shortening due to biological aging

A new study in Scientific Reports aimed to analyze the association between cross-section and longitudinal LTL changes with the consumption of soft drinks, coffee, and tea among middle-aged and older Korean men and women for six years. It also assessed any changes in the association results according to a difference in sex and age groups.

11 Jan 2023

Chromosome 8 News and Research

Using convolutional neural network to automate the identification of chromatid cohesion defects

Scientists identify the cause of leukemia in people with trisomy 21

Study unveils a key factor involved in the DNA damage response and repair

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

PARK2 duplication or microdeletion and neurological diseases

Genome editing techniques based on bacterial-artificial-chromosome in herpesvirus research

Brain over-activation could be causing seizures and social deficits in genetic subtype of autism

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

3D architecture ofAedes aegypti’s chromosomes may offer clues on gene expression, regulation

New blood test can detect prostate cancer with greater accuracy than current methods

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

Study identifies the DNA roots of resistance to targeted cancer therapy

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

Study provides an estimate of people in the United States with VEXAS syndrome

Green tea may protect against telomere shortening due to biological aging

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