High throughput screening News and Research

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High-throughput screening (HTS) allows scientists to test thousands of samples at once. These samples can be of a wide variety, and include, but are not limited to, amino acids, chemical compounds or cells.

NIH awards $2.1 million grant to counter antibiotic resistance in Gram-negative bacteria

The National Institutes of Health has awarded Dr. Walter Fast, associate professor of medicinal chemistry at The University of Texas at Austin's College of Pharmacy, a four-year $2.1 million grant to develop small-molecules that counter antibiotic resistance in Gram-negative bacteria. If successful, the research could lead to new drugs for treating bacterial infections that are resistant to most antibiotics.

1 Apr 2015

UW Medicine receives $6 million from Ellison Foundation to revolutionize care for people with Alzheimer's

Alzheimer's disease, a severe and progressive degenerative condition that leads to dementia, affects millions of people in the U.S. At present, there is no cure. Unless new treatments emerge, the Centers for Disease Control estimates that approximately 13.8 million people in the U.S. will live with Alzheimer's-related dementia by 2050.

29 Mar 2015

Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

The newest gene editing tool - called CRISPR-Cas9 - is leading to new research possibilities in cell biology and neuroscience. This includes the ability to make transgenic animal models more quickly, which helps researchers better study diseases that affect thousands of people each year.

25 Mar 2015

96-well glass vial storage plate for UHPLC

Porvair Sciences glass vial storage plate combines 96 borosilicate glass vials of 700µl into a rigid polypropylene carrier microplate to provide a superior product for storage and transportation applications.

19 Mar 2015

TSRI scientists discover novel mechanism involved in Alzheimer's, Parkinson's and ALS

Scientists from the Florida campus of The Scripps Research Institute have for the first time discovered a killing mechanism that could underpin a range of the most intractable neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS.

16 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Gramicidin-Based Fluorescence Assay can help predict drug toxicity

Sometimes, toxic side effects aren't discovered until fairly late in the drug development process, when substantial amounts of time and money have already been invested in clinical trials.

9 Feb 2015

Biolin Scientific acquires the key patent protecting multi-hole, high-throughput ion channel screening

Biolin Scientific today announces the acquisition of a key patent related to performing multi-hole, high-throughput ion channel screening.

27 Jan 2015

Removing volatile organic solvents from your 96-well microplates in minutes

The MiniVap™ blowdown evaporator from Porvair Sciences takes just minutes to remove volatile organic solvents from your 96-well microplates. The MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying.

From Chromatrap® - Porvair Sciences Ltd 26 Jan 2015

Penn researchers make breakthrough on novel anesthetics

Penn Medicine researchers, in a continuation of their groundbreaking work to better understand how anesthesia works in the body, have found the first new class of novel anesthetics since the 1970s. Their findings, published in February issue of Anesthesiology, detail the processes through which the group uncovered these compounds.

21 Jan 2015

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

BellBrook Labs, a leader in high throughput screening assays for drug discovery, announced the launch of a TR-FRET (time resolved Forster resonance energy transfer) version of the company's Transcreener UDP Assay, a high throughput screening assay for glycosyltransferases and other UDP-producing enzymes.

15 Jan 2015

Porvair Sciences releases 2015 catalogue of tissue culture plastics and epigenetic consumables

Porvair Sciences has released a new 2015 catalogue that describes its popular range of high quality tissue culture treated plastics and consumable products for Epigenetics.

From Chromatrap® - Porvair Sciences Ltd 22 Dec 2014

New E-capper from Porvair Sciences

The new E-capper from Porvair Sciences produces top quality seals and minimises the risk of repetitive strain injuries (RSI) in operators tasked with sealing deep well microplates or storage tube racks with re-useable cap mats.

From Porvair Sciences Limited 19 Nov 2014

Scientists identify new therapeutic targets, screening test to uncover compounds for memory disorders

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have identified a number of new therapeutic targets for memory disorders and have developed a new screening test to uncover compounds that may one day work against those disorders.

12 Nov 2014

Nanotechnology expert from PETA Science Consortium to outline hazard testing strategy at ECHA workshop

The PETA International Science Consortium's nanotechnology expert will present a poster titled "A Tiered-Testing Strategy for Nanomaterial Hazard Assessment" at the Topical Scientific Workshop – Regulatory Challenges in Risk Assessment of Nanomaterials being organized by the European Chemicals Agency (ECHA) on October 23 and 24 in Helsinki.

17 Oct 2014

Porvair Sciences appoints SPEware Corporation as its exclusive partner

Porvair Sciences, a world leader in applications optimised microplates and microplate equipment has appointed SPEware Corporation (Baldwin Park, CA) as its exclusive partner for supporting and servicing its UltraVap, MiniVap and UltraVap Mistral microplate sample concentration systems.

From Chromatrap® - Porvair Sciences Ltd 9 Oct 2014

EPFL scientists discover two molecules that could overcome multidrug resistance in tuberculosis

Using a high-throughput screening assay, EPFL scientists have discovered two small molecules that could overcome the multidrug resistance of the bacterium that causes tuberculosis.

9 Oct 2014

Molecular biologists awarded NIH grant to identify new compounds to fight malaria parasite

A team of molecular biologists, jointly led by Clemson University professor Jim Morris, was awarded a $151,121 grant from the National Institutes of Health to identify new compounds with anti-malarial activity for a deadly parasite species that kills hundreds of thousands of people each year.

9 Oct 2014

High-throughput ChIP analysis platform introduced in new technical article

Porvair Sciences, in conjunction with researchers at Swansea University (UK) have written a new technical article entitled 'Chromatrap® 96: a new solid-state platform for high-throughput Chromatin Immunoprecipitation (ChIP)'.

From Chromatrap® - Porvair Sciences Ltd 24 Sep 2014

High throughput screening News and Research

Further Reading

NIH awards $2.1 million grant to counter antibiotic resistance in Gram-negative bacteria

UW Medicine receives $6 million from Ellison Foundation to revolutionize care for people with Alzheimer's

Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

96-well glass vial storage plate for UHPLC

TSRI scientists discover novel mechanism involved in Alzheimer's, Parkinson's and ALS

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Gramicidin-Based Fluorescence Assay can help predict drug toxicity

Biolin Scientific acquires the key patent protecting multi-hole, high-throughput ion channel screening

Removing volatile organic solvents from your 96-well microplates in minutes

Penn researchers make breakthrough on novel anesthetics

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

Porvair Sciences releases 2015 catalogue of tissue culture plastics and epigenetic consumables

New E-capper from Porvair Sciences

Scientists identify new therapeutic targets, screening test to uncover compounds for memory disorders

Nanotechnology expert from PETA Science Consortium to outline hazard testing strategy at ECHA workshop

Porvair Sciences appoints SPEware Corporation as its exclusive partner

EPFL scientists discover two molecules that could overcome multidrug resistance in tuberculosis

Molecular biologists awarded NIH grant to identify new compounds to fight malaria parasite

High-throughput ChIP analysis platform introduced in new technical article

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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