Omicron News and Research

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Study confirms the benefit of Paxlovid as an early-stage treatment to prevent COVID-19 hospitalization

A Kaiser Permanente study confirms the benefit of nirmatrelvir-ritonavir, also known as Paxlovid, as an early-stage treatment to prevent hospitalization for people with mild to moderate COVID-19, regardless of prior immunity or age.

17 Mar 2023

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Scientists from the Republic of Korea have analyzed B-cell receptor repertoires induced by an mRNA-based coronavirus disease 2019 (COVID-19) vaccine and found that somatic hypermutations in B-cell receptor heavy chain are responsible for broadening its specificity for unexposed antigens.

16 Mar 2023

Real-world data on the effectiveness of Sotrovimab as a prophylactic against COVID-19

In a recent study posted in the medRxiv* preprint server, scientists assessed the efficacy of sotrovimab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) treatment.

16 Mar 2023

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

In a recent study published in the journal mBio, researchers in the United States evaluated rat exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC).

16 Mar 2023

Consumers more likely to use at-home COVID testing if the price drops

Researchers assess key attributes of rapid SARS-CoV-2 testing that would enable self-testing by individuals in the comfort of their homes.

16 Mar 2023

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

In a recent study posted to the bioRxiv* preprint server, researchers in the United States described a blocking enzyme-linked immunosorbent assay (ELISA) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in animals.

16 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

Four COVID-19 booster doses most effective way to prevent critical Omicron BA.5

A study published in JAMA Network Open explores the protective efficacy of previous exposure to omicron subvariants and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) omicron BA.5 infection.

15 Mar 2023

Researchers model possible COVID-19 trajectories for 2023

Researchers model predictions of the COVID-19 pandemic trajectory under different variant and intervention scenarios.

14 Mar 2023

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

A new study aimed to analyze the qualitative and quantitative impact of S-induced humoral immunity along with its ADCC capability in individuals who received a vaccination, recovered from an infection, or both.

14 Mar 2023

Do the symptom profiles among children with SARS-CoV-2 infection differ by variant type?

Researchers performed a comparative analysis of symptoms related to SARS-CoV-2 variants in children.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Kinetics of successive SARS-CoV-2 infections

Researchers compare viral kinetics of successive SARS-CoV-2 infections.

13 Mar 2023

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

A new preprint examines the response to these pathogens in the nose, which is the primary portal of entry for both.

13 Mar 2023

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

Researchers observe persistent SARS-CoV-2 replication in severe COVID-19 patient lungs.

13 Mar 2023

How effective are monovalent mRNA COVID-19 vaccine booster doses against Omicron-associated severe outcomes among adults?

Researchers from Canada investigated the efficacy of booster doses of the monovalent mRNA COVID-19 vaccine in preventing hospitalization and death during the dominance of the SARS-CoV-2 Omicron variant.

10 Mar 2023

New class of oral drugs can inhibit a diverse range of pathogenic SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections.

9 Mar 2023

Evaluating SARS-CoV-2 bivalent booster vaccine against severe COVID-19 outcomes

In a recent study posted to the medRxiv* preprint server, researchers assessed the effectiveness of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) bivalent booster vaccine against severe SARS-CoV-2 infection outcomes.

9 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Researchers conducted a prospective population survey, functional brain imaging, and a cognitive task performance test to determine whether a history of symptomatic coronavirus disease 2019 (COVID-19) was associated with psychiatric and neurocognitive symptoms.

7 Mar 2023

Omicron News and Research

Study confirms the benefit of Paxlovid as an early-stage treatment to prevent COVID-19 hospitalization

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Real-world data on the effectiveness of Sotrovimab as a prophylactic against COVID-19

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

Consumers more likely to use at-home COVID testing if the price drops

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Four COVID-19 booster doses most effective way to prevent critical Omicron BA.5

Researchers model possible COVID-19 trajectories for 2023

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

Do the symptom profiles among children with SARS-CoV-2 infection differ by variant type?

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Kinetics of successive SARS-CoV-2 infections

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

How effective are monovalent mRNA COVID-19 vaccine booster doses against Omicron-associated severe outcomes among adults?

New class of oral drugs can inhibit a diverse range of pathogenic SARS-CoV-2 strains

Evaluating SARS-CoV-2 bivalent booster vaccine against severe COVID-19 outcomes

COVID-19 patients at increased risk of developing gastrointestinal disorders

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

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