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Researchers generate and characterize the hepatic organoid culture system

Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments.

1 Nov 2021

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

A recent study published in the journal Cellular & Molecular Immunology shows that a new A.30 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can evade vaccine-induced antibodies and might spread outside the lungs extraordinarily well, with important implications for our public health response.

1 Nov 2021

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Postmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure.

29 Oct 2021

Brown fat could be the key to healthy metabolism in obese people

Not all forms are obesity are the same and brown fat could make all the difference. A study led by Florian Kiefer's research group from the Division of Endocrinology and Metabolism of the Department of Medicine III at MedUni Vienna and Vienna General Hospital shows that people who are seriously overweight (obese) who also have active brown fat have a healthier metabolism and use more energy than obese people without brown fat.

29 Oct 2021

Study focuses on the high hepatitis C rates in pregnant people

Hepatitis C virus (HCV) infection can lead to long-term health problems including liver damage, liver failure, cirrhosis, liver cancer and even death. These outcomes are especially dangerous for pregnant people and their babies.

29 Oct 2021

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A study of "dented" internal clocks seems to have provided evidence for a theory as to why people who work late or irregular hours are susceptible to weight gain and diabetes.

28 Oct 2021

A novel approach to improve the stability of Remdesivir

A recent study discusses a novel method to enhance the stability of Remdesivir.

28 Oct 2021

Malaria: An Interview with the World Health Organization

In this interview, we spoke to Dr. Akpaka Kalu, the World Health Organization's team leader for malaria in Africa, about the groundbreaking malaria vaccine rollout announcement.

28 Oct 2021

SARS-CoV-2 vaccination lowers risk of several outcomes after breakthrough infection

Researchers at the University of Oxford have conducted a study showing that vaccination against coronavirus disease 2019 (COVID-19) is associated with a lower risk of several sequelae among those who experience breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Oct 2021

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

27 Oct 2021

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Researchers at the Medical University of South Carolina report in the Journal of Viral Hepatitis that the activity levels of the proteins involved in liver scarring, or cirrhosis, begin to decrease immediately after treatment for the hepatitis C virus (HCV), suggesting the possibility of early healing.

26 Oct 2021

Study finds significant surge in liver transplantation for alcoholic hepatitis during the pandemic

Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.

26 Oct 2021

Consecutive irradiation with two lasers helps adult stem cells to transform faster

Stem cell therapy needs a lot of human cells, of a specific type. Shining a near-infrared laser on adult stem cells derived from human body fat, makes the stem cells replicate 54% faster.

26 Oct 2021

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Israeli researchers evaluate the antibody response in ICPs to assess antibody-mediated immunity following vaccination with the Pfizer-BioNTech vaccine.

26 Oct 2021

Safer, more effective therapies could help fight the obesity epidemic

Novel obesity treatments such as modulation of the gut microbiome and gene therapy are underutilized and could help fight the obesity epidemic, according to a new manuscript published in the Endocrine Society's journal, Endocrine Reviews.

26 Oct 2021

Researchers develop genetic risk score to predict development of alcohol-induced cirrhosis

An international research group led by the Centenary Institute has developed a world first genetic risk score (GRS) test able to identify patients at high-risk of developing alcohol-related cirrhosis.

26 Oct 2021

Decreasing length of hospitalization increases post-discharge complications for surgical patients

New study results suggest the national trend toward decreasing length of hospitalization after surgical procedures may come at the expense of an increasing proportion of complications occurring after patients leave the hospital.

25 Oct 2021

First investigational xenotransplantation marks a major step towards adequate organ supply

The first investigational transplant of a genetically engineered, nonhuman kidney to a human body was recently completed at NYU Langone Health—marking a major step forward in potentially utilizing an alternative supply of organs for people facing life-threatening disease.

21 Oct 2021

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

Armed with a novel strategy they developed for bolstering the body's immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice - offering a path to a functional cure for HIV and other chronic viral infections.

21 Oct 2021

UW Medicine receives NIH support to study aging cells

Efforts to understand aging cells in human tissues have received increased support from the National Institutes of Health.

20 Oct 2021

Liver News and Research

Researchers generate and characterize the hepatic organoid culture system

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Brown fat could be the key to healthy metabolism in obese people

Study focuses on the high hepatitis C rates in pregnant people

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A novel approach to improve the stability of Remdesivir

Malaria: An Interview with the World Health Organization

SARS-CoV-2 vaccination lowers risk of several outcomes after breakthrough infection

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Study finds significant surge in liver transplantation for alcoholic hepatitis during the pandemic

Consecutive irradiation with two lasers helps adult stem cells to transform faster

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Safer, more effective therapies could help fight the obesity epidemic

Researchers develop genetic risk score to predict development of alcohol-induced cirrhosis

Decreasing length of hospitalization increases post-discharge complications for surgical patients

First investigational xenotransplantation marks a major step towards adequate organ supply

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

UW Medicine receives NIH support to study aging cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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