Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Kravis Children's Hospital named one of country's top children's hospitals in pediatric specialties

The Kravis Children's Hospital at Mount Sinai ranked again among the country's top children's hospitals in pediatric specialties, according to the newly issued U.S. News & World Report's "Best Children's Hospitals" guidebook for 2015-2016.

9 Jun 2015

Electroporation technique brings higher efficiency, higher throughput genome engineering in animal models

Jackson Laboratory researchers have shown that using an electric current to deliver the CRISPR/Cas9 system, in order to engineer genetic changes in laboratory mice, is highly efficient and significantly improves the system's throughput.

9 Jun 2015

New technique slows progression of polycystic kidney disease in mice

A new technique for treating polycystic kidney disease has been identified by researchers based at the UCL Institute of Child Health. Published in the Journal of the American Society of Nephrology, the treatment, which involves targeting tiny blood and lymphatic vessels inside the kidneys, is shown to improve renal function and slow progression of disease in mice.

8 Jun 2015

Janssen begins rolling submission of daratumumab BLA to FDA for treatment of patients with multiple myeloma

Janssen Research & Development, LLC has initiated the rolling submission of its Biologic License Application (BLA) for daratumumab to the U.S. Food and Drug Administration (FDA) for the treatment of patients with multiple myeloma who have received at least three prior lines of therapy, including a proteasome inhibitor (PI) and an immunomodulatory agent (IMiD), or who are double refractory to a PI and an IMiD.

7 Jun 2015

Withholding ARBs for longer than two days after surgery significantly increases risk of postoperative death

Withholding angiotensin receptor blockers (ARBs) for longer than two days after surgery is associated with a significantly increased risk of postoperative death, according to a study of more than 30,000 patients in the VA health care system by researchers at UC San Francisco and the San Francisco VA Medical Center.

5 Jun 2015

IDMC recommends continuation of Argos’ ADAPT phase 3 trial of AGS-003 in mRCC patients

Argos Therapeutics Inc., an immuno-oncology company focused on the development and commercialization of fully personalized immunotherapies for the treatment of cancer based on the Arcelis technology platform, today announced an independent data monitoring committee (IDMC) has recommended the continuation of the company’s pivotal phase 3 ADAPT clinical trial of AGS-003 for the treatment of metastatic renal cell carcinoma (mRCC) following the first of three planned interim data analyses.

5 Jun 2015

Houston Methodist Hospital and MD Anderson Cancer Center surgeons successfully perform multi-organ transplant

Surgical teams from Houston Methodist Hospital and The University of Texas MD Anderson Cancer Center successfully transplanted, for the first time, a scalp and skull while performing kidney and pancreas transplants.

5 Jun 2015

Epsom and St Helier Hospitals extend use of VitalPAC.

Since August last year nurses on Medical wards at have been recording patient observation data on mobile electronic devices such as iPods using a digital solution called VitalPAC Nurse...

4 Jun 2015

Regulus Therapeutics begins RG-012 Phase I clinical study for treatment of Alport syndrome

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that dosing has begun in a first-in-human Phase I clinical study of RG-012, a single stranded, chemically modified oligonucleotide that binds to and inhibits the function of microRNA-21 ("miR-21").

4 Jun 2015

Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

Day in and day out, for years on end, millions of people with diabetes prick their fingers to test their blood sugar level. And many may wonder if all the careful eating, exercise and medication it takes to keep those levels under control is really worth it.

4 Jun 2015

DaVita Kidney Care releases list of top 10 U.S. travel destinations for dialysis patients

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, today released a list of the top 10 U.S. travel destinations for dialysis patients.

3 Jun 2015

Study: Intravenous nutrition source may significantly reduce toxicity of platinum-based cancer drugs

A single dose of an FDA-approved intravenous nutrition source may be able to significantly reduce the toxicity and increase the bioavailability of platinum-based cancer drugs, according to a study by Carnegie Mellon University biologists published in Scientific Reports.

3 Jun 2015

New research draws on support from patients and public to investigate impact of cardiac surgery

A University of Leicester-based research group funded by the British Heart Foundation is drawing on support from patients and members of the public to investigate why cardiac surgery can often result in serious or fatal damage to other organs in the body.

3 Jun 2015

Manchester, UCL researchers discover new technique for treating polycystic kidney disease

A new technique for treating polycystic kidney disease has been identified by researchers at The University of Manchester and UCL.

3 Jun 2015

Ultrasound becoming the most widely used imaging tool in medicine today

Mention "ultrasound" and most people likely will think of an image of a fetus in a mother's womb. But while providing peeks at the not-yet-born is one of ultrasound's most common applications, that's only a small part of the picture.

3 Jun 2015

ASCO 2015: AMGEN presents new data evaluating less-frequent dosing of kyprolis for multiple myeloma patients

Amgen today announced the initiation of the ARROW trial, a global Phase 3 study evaluating the benefit of Kyprolis®

2 Jun 2015

ASCO 2015: AMGEN presents new data evaluating less-frequent dosing of kyprolis for multiple myeloma patients

Amgen today announced the initiation of the ARROW trial, a global Phase 3 study evaluating the benefit of Kyprolis®

2 Jun 2015

Substantial pharmacogenetic information available on cardiovascular drugs

There is a wealth of published information describing interactions between drugs used to treat cardiovascular disease and the genetic variations that can affect how patients respond to them. But few heart specialists make routine use of this potentially life-saving data.

2 Jun 2015

CHLA opens doors of new Encino outpatient care center

Children's Hospital Los Angeles opened the doors of its new outpatient care center in Encino today. The pediatric medical facility, Children's Hospital Los Angeles - Encino, will be staffed by physicians who are Board-certified in pediatric specialties and subspecialties, including hematology-oncology, nephrology, neurology, orthopaedics, pediatric surgery and urology.

2 Jun 2015

Zinc levels linked to formation of kidney stone

New research on kidney stone formation reveals that zinc levels may contribute to kidney stone formation, a common urinary condition that can cause excruciating pain. The research found that zinc may be the core by which stone formation starts.

2 Jun 2015

Nephrology News and Research

Further Reading

Kravis Children's Hospital named one of country's top children's hospitals in pediatric specialties

Electroporation technique brings higher efficiency, higher throughput genome engineering in animal models

New technique slows progression of polycystic kidney disease in mice

Janssen begins rolling submission of daratumumab BLA to FDA for treatment of patients with multiple myeloma

Withholding ARBs for longer than two days after surgery significantly increases risk of postoperative death

IDMC recommends continuation of Argos’ ADAPT phase 3 trial of AGS-003 in mRCC patients

Houston Methodist Hospital and MD Anderson Cancer Center surgeons successfully perform multi-organ transplant

Epsom and St Helier Hospitals extend use of VitalPAC.

Regulus Therapeutics begins RG-012 Phase I clinical study for treatment of Alport syndrome

Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

DaVita Kidney Care releases list of top 10 U.S. travel destinations for dialysis patients

Study: Intravenous nutrition source may significantly reduce toxicity of platinum-based cancer drugs

New research draws on support from patients and public to investigate impact of cardiac surgery

Manchester, UCL researchers discover new technique for treating polycystic kidney disease

Ultrasound becoming the most widely used imaging tool in medicine today

ASCO 2015: AMGEN presents new data evaluating less-frequent dosing of kyprolis for multiple myeloma patients

ASCO 2015: AMGEN presents new data evaluating less-frequent dosing of kyprolis for multiple myeloma patients

Substantial pharmacogenetic information available on cardiovascular drugs

CHLA opens doors of new Encino outpatient care center

Zinc levels linked to formation of kidney stone

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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