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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

The Korea Advanced Institute of Science and Technology (KAIST) and their collaborators have conducted a groundbreaking study targeting 'jumping genes' in the entire genomes of the human large intestine.

25 May 2023

New review unravels phthalates’ role in heart disease

Researchers review existing data on the impact of phthalate exposure on cardiovascular health.

25 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

New tool shows early promise to help reduce the spread of antimicrobial resistance

A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

25 May 2023

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

The study aimed to predict the future human Buruli ulcer case locations via statistical modelling.

25 May 2023

People with Alzheimer's disease more likely to develop epilepsy and vice versa

People with a genetic predisposition for Alzheimer's disease may have an increased risk of epilepsy and people with a certain type of epilepsy may have an increased risk of developing Alzheimer's disease, according to a study published in the May 24, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

25 May 2023

Precision nutrition and the gut microbiome: the impact of blueberries

Researchers explored the impacts of precision nutrition on gut microbiome variation.

25 May 2023

Novel regulators of COPD determined by epigenetic profiling

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease).

25 May 2023

Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

Epstein-Barr virus (EBV) has a significant role in the development of multiple sclerosis (MS), with evidence linking EBV infection to increased MS risk and immune dysregulation. Understanding the mechanisms underlying this connection is crucial for advancing MS therapies and prevention strategies.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

Newly developed method can help identify the special differences in genetic information

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

22 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage - a cause and consequence of many diseases.

22 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

Unlocking gut health: How indoor environment impacts the microbiota balance

Research paper highlights the importance of a diverse and balanced gut microbiota for human health, while emphasizing the need for further understanding of the impact of indoor microbiome and metabolites on gut microbiota.

21 May 2023

Unraveling the origins of humanity: New research challenges single-origin theory

Researchers explore the complex demographic history of Homo sapiens in Africa, revealing a reticulated population structure dating back to Marine Isotope Stage 5. The study challenges previous assumptions about archaic hominin contributions and emphasizes the significance of employing diverse models for robust inferences about ancient human history.

21 May 2023

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Research paper discusses the differences in microbiota between high and low IgA subjects after the second dose of the COVID-19 vaccine. The study found that certain microbial features in breast milk can predict levels of anti-SARS-CoV-2 antibodies in breast milk one week post-second dose.

21 May 2023

DNA News and Research

Further Reading

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

New review unravels phthalates’ role in heart disease

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

New tool shows early promise to help reduce the spread of antimicrobial resistance

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

People with Alzheimer's disease more likely to develop epilepsy and vice versa

Precision nutrition and the gut microbiome: the impact of blueberries

Novel regulators of COPD determined by epigenetic profiling

Combination of genetic and environmental factors increases the risk of cleft lip

The adaptive immunity of human endemic viruses

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

The antimicrobial potential of nanoparticles

Newly developed method can help identify the special differences in genetic information

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

Unlocking gut health: How indoor environment impacts the microbiota balance

Unraveling the origins of humanity: New research challenges single-origin theory

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Understanding the DNA Damage Response in Innate Immunity eBook

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