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New tool could help identify patients most likely to benefit from chemoprevention

A team of scientists, led by researchers at University of California, San Diego Moores Cancer Center and The University of Texas MD Anderson Cancer Center, report that a genetic biomarker called loss of heterozygosity or LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer.

6 Nov 2015

Tai Chi, better sleep quality reduce inflammation, depression and age-related morbidities

Inflammatory processes occur throughout the body, with a primary function of promoting healing after injury. However, when too active, these inflammatory processes can also damage the body in many ways, and may contribute to heart disease, stroke, certain cancers, and other significant medical problems.

6 Nov 2015

Genetic reduction of AMPK enzyme can prevent or delay hearing loss

A mitochondrial defect is responsible for a type of human hereditary deafness that worsens over time and can lead to profound hearing loss.

6 Nov 2015

UCSF scientists identify eye drop chemical that may reverse cataracts

A chemical that could potentially be used in eye drops to reverse cataracts, the leading cause of blindness, has been identified by a team of scientists from UC San Francisco (UCSF), the University of Michigan (U-M), and Washington University in St. Louis (WUSTL).

6 Nov 2015

New treatment may help patients with chronic renovascular disease

A new treatment may help patients with a chronic kidney condition that can also lead to heart problems and premature death, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

6 Nov 2015

Circulating protein predicts risk of chronic kidney disease

Make room, cholesterol. A new disease marker is entering the medical lexicon: suPAR, or soluble urokinase-type plasminogen activator receptor.

6 Nov 2015

Hutchison MediPharma begins sulfatinib Phase I trial in US

Hutchison China MediTech Limited today announces that Hutchison MediPharma Limited ("HMP"), its drug R&D subsidiary, has initiated the Phase I clinical trial of sulfatinib (HMPL-012) in the United States.

6 Nov 2015

Researchers identify new regulatory pathway that may play vital role in basal-like breast cancer

Researchers have identified a new regulatory pathway that may play an important role in basal-like breast cancer (BLBC), a particularly aggressive form of breast cancer often referred to as "triple negative." This pathway may serve as a target for the development of an effective therapeutic.

5 Nov 2015

Researchers uncover important mechanism that could help protect against infection, allergy and cancer

New research has uncovered an important mechanism in the drive to understand immunological processes that protect us against infection, allergy and cancer.

5 Nov 2015

Researchers discover potential solution for side effects of immunotherapy treatment for Alzheimer's

It is estimated that 46.8 million people worldwide are living with dementia, with Alzheimer's disease the most common form.

5 Nov 2015

New protein supplement lowers cholesterol, prevents osteoporosis

Scientists developed a supplement to maintain optimal health that contributes to the growth and development of children and adolescents. It also prevents osteoporosis and certain cancers such as breast and prostate.

5 Nov 2015

Communication network makes astrocytomas more resistant to treatment

Astrocytomas are special type of brain tumours that are difficult to treat, because they do not respond to standard forms of treatment. One reason for this resistance could be their ability to form a communication network.

5 Nov 2015

Better understanding of hibernation could help researchers develop treatments for cardiac disease

Wintry weather means hats and scarves for some mammals, and hibernation for others. Hibernation dramatically lowers body temperatures, heart rates and oxygen consumption -- things that would be fatal to other animals. A team reports in ACS' Journal of Proteome Research a study of the proteins and genes that allow squirrels' hearts to stay healthy during the winter.

5 Nov 2015

New vaccine candidate shows great promise at fighting respiratory syncytial virus

Johns Hopkins Bloomberg School of Public Health researchers say a new candidate vaccine against respiratory syncytial virus (RSV) made with a weakened version of the virus shows great promise at fighting the disease, the leading cause of hospitalization for children under the age of one in the U.S.

5 Nov 2015

Researchers identify mechanisms underlying postnatal organ maturation

Any expectant mother will tell you that she wants her baby's organs to develop properly in the womb. What she may not realize, however, is that a child's internal organs continue to develop for months and years after birth. This critical period is full of cellular changes that transform the organization and function of most tissues. But the exact mechanisms underlying postnatal organ maturation are still a mystery.

5 Nov 2015

Harnessing the brain's immune system to combat Alzheimer's disease

A new study appearing in the Journal of Neuroinflammation suggests that the brain's immune system could potentially be harnessed to help clear the amyloid plaques that are a hallmark of Alzheimer's disease.

5 Nov 2015

Researchers successfully repair nerve cell damage in Alzheimer's dementia

In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Prof. Dr. Ulrike Müller and a team of French scientists have succeeded in largely "repairing" the nerve cell damage typical in this disease.

5 Nov 2015

CK5 protein marks ovarian cancer likely to be resistant to cisplatin

A University of Colorado Cancer Center study recently published in the International Journal of Gynecological Cancer shows that protein cytokeratin 5 (CK5), known to be a marker of poor prognosis in breast cancer, also marks ovarian cancers likely to be resistant to the common chemotherapy cisplatin.

5 Nov 2015

JEDI T-cells provide unique technology to study, visualize immune responses and immunotherapies

When it comes to fending off disease and helping prevent people from falling ill, the body's immune system -- armed with T-cells that help eliminate cancer cells, virus-infected cells and more -- is second to none. But exactly how the immune system works remains, in many ways, a mystery, as there are numerous cell types whose functions and interactions with our immune systems have not been well understood.

5 Nov 2015

Perisylvian polymicrogyria gene found

Researchers have identified the genetic basis for bilateral perisylvian polymicrogyria, the most common form of regional polymicrogyria.

4 Nov 2015

G Protein News and Research

New tool could help identify patients most likely to benefit from chemoprevention

Tai Chi, better sleep quality reduce inflammation, depression and age-related morbidities

Genetic reduction of AMPK enzyme can prevent or delay hearing loss

UCSF scientists identify eye drop chemical that may reverse cataracts

New treatment may help patients with chronic renovascular disease

Circulating protein predicts risk of chronic kidney disease

Hutchison MediPharma begins sulfatinib Phase I trial in US

Researchers identify new regulatory pathway that may play vital role in basal-like breast cancer

Researchers uncover important mechanism that could help protect against infection, allergy and cancer

Researchers discover potential solution for side effects of immunotherapy treatment for Alzheimer's

New protein supplement lowers cholesterol, prevents osteoporosis

Communication network makes astrocytomas more resistant to treatment

Better understanding of hibernation could help researchers develop treatments for cardiac disease

New vaccine candidate shows great promise at fighting respiratory syncytial virus

Researchers identify mechanisms underlying postnatal organ maturation

Harnessing the brain's immune system to combat Alzheimer's disease

Researchers successfully repair nerve cell damage in Alzheimer's dementia

CK5 protein marks ovarian cancer likely to be resistant to cisplatin

JEDI T-cells provide unique technology to study, visualize immune responses and immunotherapies

Perisylvian polymicrogyria gene found

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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