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Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

SMART protocol improves cognitive function, psychological well-being in laboratory participants

Many people believe that they can't change their brains, or that their brain health will inevitably decline as they age.

28 Jan 2021

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

Working to develop new treatments for osteoarthritis, researchers at Washington University School of Medicine in St. Louis have genetically engineered cartilage to deliver an anti-inflammatory drug in response to activity similar to the bending of a knee or other motions that put stress on joints.

27 Jan 2021

New trial to look at reducing transmission of Covid-19 in care homes

A new trial, led by experts from the University of Nottingham, will look at reducing the transmission of Covid-19 and its severity in care homes, thanks to funding from the National Institute for Health Research.

27 Jan 2021

Salk scientists receive $1.2 million from Larry L. Hillblom Foundation to study aging mechanisms

A collaborative team of Salk scientists led by Professor John Reynolds will receive $1.2 million over four years as part of a Network Grant from the Larry L. Hillblom Foundation to examine aging across the life span, including age-related neurodegenerative diseases such as Alzheimer's disease.

27 Jan 2021

Remdesivir, given to half of hospitalized covid patients in U.S., is big win for Gilead — boosted by taxpayers

It was the end of April — just as the U.S. confirmed its millionth covid-19 case and 50,000 deaths — when White House adviser Dr. Anthony Fauci announced "highly significant" news about a drug called remdesivir.

27 Jan 2021

New compound may slow aging and age-related diseases

A compound that extends lifespan in a tiny nematode worm slows bone loss in aging mice. That surprising result comes from a longitudinal and functional study of 700 aging mice at the Buck Institute, a project that provides a treasure trove of data for researchers aiming to develop therapeutics to slow aging and age-related diseases.

27 Jan 2021

Two-drug combination approach could be effective against bone cancer

An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis.

27 Jan 2021

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Cell phone data that is routinely collected by telecommunications providers can reveal changes of behavior in people who are diagnosed with a flu-like illness, while also protecting their anonymity, a new study finds.

26 Jan 2021

Novel platform uses modified virus to combat pancreatic cancer

Researchers from Queen Mary University of London and Zhengzhou University have developed a powerful therapeutic platform that uses a modified virus for the treatment of pancreatic cancer.

26 Jan 2021

Genetic interactions may shed light on NGLY1 deficiency

In 2012, four-year-old Bertrand Might became the first-ever patient diagnosed with a rare genetic disorder called N-glycanase (NGLY1) deficiency. The discovery of this condition and Bertrand's diagnosis allowed doctors to look for other children with the same genetic defect. Since then, more than 60 additional patients have been found.

26 Jan 2021

£1.6 million grant awarded to advance development of MND drug candidate

Researchers from the University of Sheffield's Institute for Translational Neuroscience have been awarded a £1.6 million grant from the Medical Research Council.

26 Jan 2021

NIH launches database to collect information about COVID-19-related neurological problems

A new database will collect information from clinicians about COVID-19-related neurological symptoms, complications, and outcomes as well as COVID-19 effects on pre-existing neurological conditions.

26 Jan 2021

New partnership to develop test for predicting disease course in pediatric Crohn's patients

The Crohn's & Colitis Foundation, the leading non-profit organization focused on both research and patient support for inflammatory bowel disease (IBD), has entered into a partnership with LifeArc, an independent medical research charity that advances translation of early science into health care treatments or diagnostics, to potentially develop the first clinical lab test to predict disease course in pediatric patients with Crohn's disease and response to treatment.

25 Jan 2021

Promising nanobodies against COVID-19 produced by llamas

News-Medical speaks to Dr. David Brody about his latest research that involved discovering nanobodies produced by llamas that could help combat coronavirus.

25 Jan 2021

Lack of sleep, stress, mental health problems can lead to PCS-like symptoms

A new study suggests that a lot of people might be going through life with symptoms that resemble concussion - a finding supporting researchers' argument that athletes recovering from a brain injury should be assessed and treated on a highly individualized basis.

22 Jan 2021

New study to measure how sedentary behavior can impact health

A new worldwide study funded by the British Heart Foundation will measure how certain physical behaviours, such as sitting for long periods of time, can impact health.

21 Jan 2021

Study finds racial disparities in side-specific biological aging of the colon

The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer - the cancer that killed beloved "Black Panther" star Chadwick Boseman at only 43.

21 Jan 2021

Researchers evaluate the accuracy of NEWS2 scoring system for predicting COVID outcomes

In the first systematic large-scale evaluation of the UK National Early Warning Risk Score (NEWS) 2 as a scoring system for predicting severe COVID-19 outcomes in patients, researchers at King's College London have found poor-to-moderate accuracy for identifying patients at risk of being transferred to intensive care units (ICUs) or dying after 14 days of hospitalization.

20 Jan 2021

Researchers discover rare genetic disorder that affects the brain, heart and facial features

Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features.

20 Jan 2021

Medical Research News and Research

Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

SMART protocol improves cognitive function, psychological well-being in laboratory participants

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

New trial to look at reducing transmission of Covid-19 in care homes

Salk scientists receive $1.2 million from Larry L. Hillblom Foundation to study aging mechanisms

Remdesivir, given to half of hospitalized covid patients in U.S., is big win for Gilead — boosted by taxpayers

New compound may slow aging and age-related diseases

Two-drug combination approach could be effective against bone cancer

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Novel platform uses modified virus to combat pancreatic cancer

Genetic interactions may shed light on NGLY1 deficiency

£1.6 million grant awarded to advance development of MND drug candidate

NIH launches database to collect information about COVID-19-related neurological problems

New partnership to develop test for predicting disease course in pediatric Crohn's patients

Promising nanobodies against COVID-19 produced by llamas

Lack of sleep, stress, mental health problems can lead to PCS-like symptoms

New study to measure how sedentary behavior can impact health

Study finds racial disparities in side-specific biological aging of the colon

Researchers evaluate the accuracy of NEWS2 scoring system for predicting COVID outcomes

Researchers discover rare genetic disorder that affects the brain, heart and facial features

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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