Polymerase News and Research

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DIATHERIX Laboratories granted EUA for H1N1-09 Influenza Test

DIATHERIX Laboratories, Inc. is pleased to announce it has been granted emergency use authorization (EUA) from the U.S. Food and Drug Administration (FDA) for its DIATHERIX H1N1-09 Influenza Test.

14 Oct 2009

Manual microdissection to remove biopsy cavities from breast cancer specimens essential

Genomic Health, Inc. today announced results from a study demonstrating the critical role of manual microdissection to remove all biopsy cavities from breast cancer specimens. Genomic Health's Oncotype DX is the only commercially available breast cancer test that employs manual microdissection following review by a board certified surgical pathologist with breast expertise to predict a patient's benefit from chemotherapy and risk of disease recurrence.

9 Oct 2009

NHGRI support research to accelerate development of innovative sequencing technologies

GE Global Research, the technology development arm for the General Electric Company (NYSE: GE), today announced that scientists in their Biosciences Lab have been awarded a second round of funding from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), to continue research that could reduce the cost and time of sequencing of an entire human genome to less than $1,000, in under a day.

9 Oct 2009

NIH awards $1.9 million grant to Pacific Biosciences

Pacific Biosciences, a private company developing a disruptive technology platform for real-time detection of biological events at single molecule resolution, today announced that it has received grants totaling more than $1.9 million from the National Institutes of Health (NIH) as part of the American Recovery & Reinvestment Act of 2009 Research and Research Infrastructure “Grand Opportunities” grants program.

8 Oct 2009

Quest Diagnostics' DNA testing for gene variants help improve outcomes for stent recipients

DNA testing for gene variants that can increase the risk of major coronary events in certain patients taking the anti-clotting drug Plavix® (clopidogrel bisulfate) is now being performed by Quest Diagnostics for Scripps Health patients electing to undergo coronary stent procedures.

From Quest Diagnostics 8 Oct 2009

Scientists create new technology to improve detection of leukemia cells in bone marrow

Scientists have created a viable technology to improve the detection of leukemia cells in bone marrow.

7 Oct 2009

PSI-879 nominated as second development candidate for treating HCV infection

Pharmasset, Inc. announced today the nomination of PSI-352879 (PSI-879) as a second development candidate from two series of purine analogs for the treatment of chronic hepatitis C virus (HCV) infection.

7 Oct 2009

Researchers screen decades-old frozen infant stool samples to detect norovirus

A search through decades-old frozen infant stool samples has yielded rich dividends for scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

3 Oct 2009

Scarab Genomics releases new E. Coli strain

ScarabXpress is the latest strain in the multiple-deletion series (MDS) of Scarab Genomics Clean Genome® E. coli. Based on the MDS™42 strain, ScarabXpress T7lac contains a chromosomal copy of the T7 RNA polymerase gene expressed from a unique, tightly controlled lac promoter.

29 Sep 2009

Research study indicates presence of two stable bacterial ecosystems in the gut

Small-bowel transplant patients with an ileostomy -- an opening into their small bowel -- have a very different population of bacteria living in their gut than patients whose ileostomy has been closed, researchers from UC Davis and Georgetown University Medical Center have found. The results are published online Sept. 14 in the Proceedings of the National Academy of Sciences.

16 Sep 2009

FDA clears Olerup SSP’s Taq-polymerase-free HLA typing kit for sale in the U.S.

Olerup SSP, a wholly owned subsidiary of LinkMed (STO:LMED), has had its Taq-polymerase-free HLA typing kit registered and cleared by the FDA. This means that Olerup SSP’s entire product range for HLA typing, with or without Taq polymerase, can now be marketed and sold to a greater number of healthcare centers in North America.

15 Sep 2009

Study reveals that daily bathroom showers may deliver pathogenic bacteria

While daily bathroom showers provide invigorating relief and a good cleansing for millions of Americans, they also can deliver a face full of potentially pathogenic bacteria, according to a surprising new University of Colorado at Boulder study.

15 Sep 2009

Phase II trial of ANA598 commenced by Anadys Pharmaceuticals

Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) announced today that dosing has begun in a Phase II trial of ANA598 in patients chronically infected with hepatitis C virus (HCV). The study will evaluate ANA598 over 12 weeks, taken in combination with pegylated interferon-alpha and ribavirin, in treatment naive HCV patients. ANA598 is an investigational, oral, non-nucleoside polymerase inhibitor.

9 Sep 2009

BioTrove partners with FDA to investigate the utility of SNAP system

BioTrove announced a collaboration with the U.S. Food and Drug Administration’s Center for Biologics Evaluation and Research to investigate the utility of the company’s Standardized NanoArray PCR (SNAP) gene expression profiling system for the rapid and specific detection of pathogens in the nation’s blood supply.

8 Sep 2009

New H1N1 Influenza detection test used to diagnose Australia's first swine flu victim

When the first cases of H1N1 Influenza (swine flu) were reported in Mexico in April, UQ researchers got to work developing a test to diagnose the virus.

4 Sep 2009

Vaccinating women against HPV prevents breast cancer

Vaccinating women against the human papillomavirus (HPV) may prevent some forms of breast cancer and save tens of thousands of lives each year, new Australian research suggests.

4 Sep 2009

Rapid, accurate and cost-efficient testing of DNA with the Nanogap Sensor Array

A novel electronic sensor array for more rapid, accurate and cost-efficient testing of DNA for disease diagnosis and biological research has been developed by scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN).

27 Aug 2009

Nanogap sensor array for ultra-sensitive detection of human DNA

Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. Such tests are done for criminal investigation, disease diagnosis, and other purposes.

27 Aug 2009

Viral polymerase may provide a new therapeutic target for host-adapted avian influenza

Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. The related report by Gabriel et al, "Spread of Infection and Lymphocyte Depletion in Mice Depends on Polymerase of Influenza Virus" appears in the September 2009 issue of the American Journal of Pathology.

26 Aug 2009

InterMune receives $20 million event payment from Roche for initiating the Phase 2b trial of RG7227/ ITMN-191

Roche (SIX: ROG.VX; RO.S, OTCQX: RHHBY) and InterMune, Inc. (Nasdaq: ITMN) today announced that the first patient has been dosed in a Phase 2b study evaluating the hepatitis C virus (HCV) protease inhibitor, RG7227/ ITMN-191, in combination with PEGASYS(R) (pegylated interferon alfa-2a) and COPEGUS(R) (ribavirin). The study, to be conducted at 45 sites globally, will further define the safety and efficacy profile of RG7227/ ITMN-191, for a treatment duration of up to 24 weeks. Approximately 300 treatment-naive patients chronically infected with HCV genotype 1 - the most difficult to treat form of the virus - will participate.

20 Aug 2009

Polymerase News and Research

DIATHERIX Laboratories granted EUA for H1N1-09 Influenza Test

Manual microdissection to remove biopsy cavities from breast cancer specimens essential

NHGRI support research to accelerate development of innovative sequencing technologies

NIH awards $1.9 million grant to Pacific Biosciences

Quest Diagnostics' DNA testing for gene variants help improve outcomes for stent recipients

Scientists create new technology to improve detection of leukemia cells in bone marrow

PSI-879 nominated as second development candidate for treating HCV infection

Researchers screen decades-old frozen infant stool samples to detect norovirus

Scarab Genomics releases new E. Coli strain

Research study indicates presence of two stable bacterial ecosystems in the gut

FDA clears Olerup SSP’s Taq-polymerase-free HLA typing kit for sale in the U.S.

Study reveals that daily bathroom showers may deliver pathogenic bacteria

Phase II trial of ANA598 commenced by Anadys Pharmaceuticals

BioTrove partners with FDA to investigate the utility of SNAP system

New H1N1 Influenza detection test used to diagnose Australia's first swine flu victim

Vaccinating women against HPV prevents breast cancer

Rapid, accurate and cost-efficient testing of DNA with the Nanogap Sensor Array

Nanogap sensor array for ultra-sensitive detection of human DNA

Viral polymerase may provide a new therapeutic target for host-adapted avian influenza

InterMune receives $20 million event payment from Roche for initiating the Phase 2b trial of RG7227/ ITMN-191

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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