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New study to evaluate bleeding complications in patients undergoing high-risk PCI with Impella

A new multicenter, single-arm, open-label study is the first to exclusively assess bleeding complications in patients undergoing high-risk percutaneous coronary interventions (PCI) with Impella with independent adjudication via a clinical events adjudication committee and will gather meaningful real-world data based on contemporary practice.

5 Jul 2023

Clinical trial of three-month TB treatment regimen closed due to high rate of unfavorable outcomes

The first clinical trial of a three-month tuberculosis (TB) treatment regimen is closing enrollment because of a high rate of unfavorable outcomes with the investigational course of treatment.

5 Jul 2023

Purecap method offers hope for purer and safer mRNA vaccines

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

5 Jul 2023

Study finds correlation between oral microbiome, alcohol metabolism, and hangover severity

Hangovers are common among people who drink alcohol. Previous research showing that a hangover's combination of both mental and physical misery can occur after a single episode of alcohol consumption also revealed that a rapid breakdown of alcohol into acetaldehyde is associated with less severe hangovers.

4 Jul 2023

Critical questions raised for evaluation of anti-amyloid immunotherapies in Alzheimer's treatment

Anti-amyloid immunotherapies for Alzheimer's disease require thorough evaluation of their efficacy, safety, and cost-effectiveness. Key questions regarding statistical analyses, treatment effects, and disease course modification guide evidence-based consideration of these drugs.

4 Jul 2023

A novel RSV vaccine that could be effective across all ages

Researchers evaluate the in vivo efficacy of a respiratory syncytial virus vaccine in old and young rats.

4 Jul 2023

MHRA's new corporate plan sets out goals for patient safety and access to innovative medical products

A new, visionary Corporate Plan, setting out how the Medicines and Healthcare products Regulatory Agency plans to keep patients safe by enabling access to innovative, safe and effective medical products over the coming three years, has been published today (4 July 2023).

4 Jul 2023

EPFL scientists develop an innovative method for reconstructing Tau fibrils

EPFL scientists have developed ClearTau, an innovative method and platform for reconstructing aggregates of the protein Tau found in Alzheimer's disease and other neurodegenerative diseases.

4 Jul 2023

SYS6006 investigational COVID-19 mRNA vaccine shows promise as fourth dose booster

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 600 million confirmed cases and 6.5 million deaths worldwide.

4 Jul 2023

Smoking and HPV found to increase risk of head and neck cancer

Tobacco smoking and human papillomavirus (HPV) are both well-known risk factors for head and neck cancer, but there is ample evidence to show they can interact to increase still further the risk of contracting the disease, according to a study by scientists at the University of São Paulo (USP) in Brazil and the University of Chile.

3 Jul 2023

Mutations in AGC kinase motif linked to colorectal cancer growth

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor growth, resist therapies, and hasten its spread from the original site to the bloodstream or other organs.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

Caffeine found to be most effective for treating birth asphyxia

Brain damage caused by oxygen deficiency at birth is one of the main causes of death in newborns worldwide. Using a small animal model, researchers from the University Hospital Bonn (UKB) and DZNE tested treatment with 25 different active agents.

3 Jul 2023

New COVID-19 mRNA vaccine is safe and highly immunogenic as a heterologous booster: Study

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 600 million confirmed cases and 6.5 million deaths worldwide.

3 Jul 2023

Can the keto diet be used to treat migraines?

Dietary interventions, such as ketogenic therapy, show promise in reducing the frequency and severity of headaches, providing potential relief for individuals worldwide.

2 Jul 2023

Study finds nighttime speed limits not effective in reducing e-scooter injuries

Study aimed to examine whether nighttime speed restrictions are associated with the incidence of e-scooter-related injuries. The results showed that the nighttime speed limit was not associated with reduced injury incidence.

2 Jul 2023

OVUM highlights the potential of AI in revolutionizing IVF

The reproductive and fertility wellness brand, OVUM, highlights the potential of artificial intelligence (AI) in revolutionizing the In vitro fertilization (IVF) field.

1 Jul 2023

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

Towards Zika preparedness: immunogenicity insights from vaccine research

Study assesses the safety and immunogenicity of an inactivated Zika virus vaccine candidate.

30 Jun 2023

Advances in influenza research

This interview with Dr. Mohammad S Safiarian, Associate Product Manager at Sino Biological, discusses the advances in influenza research and how effective vaccines are developed.

From Sino Biological Inc. 30 Jun 2023

Efficacy News and Research

New study to evaluate bleeding complications in patients undergoing high-risk PCI with Impella

Clinical trial of three-month TB treatment regimen closed due to high rate of unfavorable outcomes

Purecap method offers hope for purer and safer mRNA vaccines

Study finds correlation between oral microbiome, alcohol metabolism, and hangover severity

Critical questions raised for evaluation of anti-amyloid immunotherapies in Alzheimer's treatment

A novel RSV vaccine that could be effective across all ages

MHRA's new corporate plan sets out goals for patient safety and access to innovative medical products

EPFL scientists develop an innovative method for reconstructing Tau fibrils

SYS6006 investigational COVID-19 mRNA vaccine shows promise as fourth dose booster

Smoking and HPV found to increase risk of head and neck cancer

Mutations in AGC kinase motif linked to colorectal cancer growth

Base editing shows promise for treating sickle cell disease and beta thalassemia

Caffeine found to be most effective for treating birth asphyxia

New COVID-19 mRNA vaccine is safe and highly immunogenic as a heterologous booster: Study

Can the keto diet be used to treat migraines?

Study finds nighttime speed limits not effective in reducing e-scooter injuries

OVUM highlights the potential of AI in revolutionizing IVF

Spanish researchers develop new immunotherapy combination for liver cancer

Towards Zika preparedness: immunogenicity insights from vaccine research

Advances in influenza research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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