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New study unravels complete sequence of DNA repair mechanism

Every living organism has DNA, and every living organism engages in DNA replication, the process by which DNA makes an exact copy of itself during cell division. While it's a tried-and-true process, problems can arise.

25 Jan 2021

Can the onset and end of an epidemic be predicted? A SARS-CoV-2 modeling case study

A recent study by researchers in France shows how differences in infection history and viral spread patterns are important factors in predicting the time course of a localized epidemic of SARS-CoV-2.

22 Jan 2021

Researchers update automated computation tool for SARS-CoV-2 genome analysis

Researchers updated a previous version of an automated tool to include SARS-CoV-2 genome analysis. Genome analysis using the freely available software could help track the evolution of the virus and promptly identify variants that increase viral transmission or virulence.

22 Jan 2021

SARS-CoV-2’s nonstructural proteins dysregulate immune responses, study finds

Researchers provide an overview of SARS-CoV-2 and its life cycle pathways, addressing the functional changes in the viral proteins, providing important strategic clues to help that may help in the ongoing development of therapies against COVID-19.

22 Jan 2021

Genomic test has lower prognostic accuracy in minority patients with breast cancer

Black women have higher recurrence and mortality rates than non-Hispanic white women for certain types of breast cancer, according to a University of Illinois Chicago researcher's study published recently in JAMA Oncology.

22 Jan 2021

SARS-CoV-2 variants appear to arise independently of local transmission

Researchers at the University of Michigan in the United States have cautioned against only using within-host minor genetic variations to resolve the genomic epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

21 Jan 2021

Study examines association between gut mycobiome and Parkinson’s disease

The bacterial gut microbiome is strongly associated with Parkinson's disease (PD), but no studies had previously investigated he role of fungi in the gut.

21 Jan 2021

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Using SARS-CoV-2, a team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce vaccines.

21 Jan 2021

Researchers discover rare genetic disorder that affects the brain, heart and facial features

Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features.

20 Jan 2021

COVID-19 has transformed the world of vaccines

Researchers at GlaxoSmithKline (GSK) in Italy and Belgium say the coronavirus disease 2019 (COVID-19) pandemic is transforming the world of vaccinology by accelerating vaccine development and the availability of powerful technologies.

20 Jan 2021

The structure dynamics of the SARS-CoV-2 genome in cells, cell lysates and virions

Now, a new preprint research paper posted to the bioRxiv server describes the structures observed during the lifecycle of the RNA virus in terms of both canonical and alternative structures, RNA-RNA interactions, and replication regulation.

19 Jan 2021

A common genetic variant identified as risk factor for stroke

A team of Geisinger researchers has identified a common genetic variant as a risk factor for stroke, especially in patients older than 65.

19 Jan 2021

RECoVERY: New open-source software developed for analyzing SARS-CoV-2 genomes

Researchers report an open-source platform-independent tool for building SARS-CoV-2 genomes from raw sequencing reads. The tool can be used without any extra hardware or software and be run using any browser from a desktop or mobile.

19 Jan 2021

Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants

Viral genome sequencing of wastewater can detect new SARS-CoV-2 variants before they are detected by local clinical sequencing, according to a new study reported in mBio, an open-access journal of the American Society for Microbiology.

19 Jan 2021

Research finds new evidence about the mechanisms controlling skin repair and regeneration

As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal.

19 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

Prolonged shedding and multiple mutations 154 days after initial SARS-CoV-2 diagnosis reported

An interesting new preprint published on the medRxiv server describes an immunosuppressed patient with coronavirus disease 2019 (COVID-19) who continued to shed the virus for an astounding 154 days. During this period, the virus underwent numerous mutations.

19 Jan 2021

Genomic News and Research

New study unravels complete sequence of DNA repair mechanism

Can the onset and end of an epidemic be predicted? A SARS-CoV-2 modeling case study

Researchers update automated computation tool for SARS-CoV-2 genome analysis

SARS-CoV-2’s nonstructural proteins dysregulate immune responses, study finds

Genomic test has lower prognostic accuracy in minority patients with breast cancer

SARS-CoV-2 variants appear to arise independently of local transmission

Study examines association between gut mycobiome and Parkinson’s disease

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Researchers discover rare genetic disorder that affects the brain, heart and facial features

COVID-19 has transformed the world of vaccines

The structure dynamics of the SARS-CoV-2 genome in cells, cell lysates and virions

A common genetic variant identified as risk factor for stroke

RECoVERY: New open-source software developed for analyzing SARS-CoV-2 genomes

Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants

Research finds new evidence about the mechanisms controlling skin repair and regeneration

New method could provide additional insight into brain tumors

Prolonged shedding and multiple mutations 154 days after initial SARS-CoV-2 diagnosis reported

WHO Emergency Committee to review emerging SARS-CoV-2 variants

Global scientists are intensifying research on COVID-19

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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