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Hyperferritinemia associated with increased illness severity in COVID-19

Yehuda Shoenfeld is the world's leading expert in the research, treatment and prevention of autoimmune diseases.

22 Apr 2020

Study creates a new platform to study single-cell genomics of many diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

22 Apr 2020

New findings could make immunotherapy treatments effective for more cancer patients

Scientists have developed a new way to map the molecules on tumour cells that flag their presence to the immune system, according to a study published today in eLife.

22 Apr 2020

AI may help eliminate use of biopsy for brain cancer patients

Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.

21 Apr 2020

Study uncovers cause of blood-vessel leakiness in eye diseases

Scientists have identified a key step in the process that leads to leaky vessels and harmful swelling in eye diseases, according to a new study published today in eLife.

21 Apr 2020

Mutations in novel coronavirus make it more dangerous

A new report published on the preprint server medRxiv in April 2020 reveals that the novel coronavirus SARS-CoV-2 shows the presence of new mutations acquired within infected human cases, which significantly increase its ability to cause human disease.

20 Apr 2020

Scientists delay onset of amyotrophic lateral sclerosis in mice

A team of researchers led by scientists at the University of Toronto has delayed the onset of amyotrophic lateral sclerosis in mice.

20 Apr 2020

Novel coronavirus mutation could spell trouble for vaccine development

New research shows that the novel coronavirus is undergoing mutations that could make it challenging to develop a vaccine against. There are a few vaccine candidates that are in the making to prevent COVID-19. With a potential for mutation, the vaccines that are being developed now may not work against the emergent mutated strains worry Taiwanese and Australian researchers. The study is titled, “Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of 2 RBD mutant with lower ACE2 binding affinity.”

19 Apr 2020

Scientists unveil novel coronavirus variants in India

The global coronavirus disease COVID-19 pandemic is ravaging the world, affecting 185 countries and territories and infecting 2.4 million people. Now, a team of scientists aims to shed light on the variants of the novel coronavirus strains in India, showing how changes correspond to its transmission and how it causes disease.

19 Apr 2020

Study shows huge effect of obesity on pancreatic cancer development

Pancreatic cancer is expected to become the second-deadliest cancer in the United States by 2030, driven in part by rising obesity rates.

17 Apr 2020

Theoretical aspects of cancer evolution could pave way to new anti-cancer therapies

New treatments designed to prevent cancer from developing, based on changing the microenvironment in which cancer cells evolve, could be both feasible and effective.

17 Apr 2020

Solving the mystery of unidentified late-onset neurodegenerative disorder

When a patient with puzzling neurological symptoms enrolled in the Undiagnosed Diseases Network, researchers led by Dr. Hugo J. Bellen were set on solving the mystery.

16 Apr 2020

China with the world: COVID-19 experts dialogues - the 2nd talk transcript

Q: Starting from the patient admission to the hospital, what is your rule for ventilation? Do you start from HFNC, CPAP, NIV or go directly to intubation and invasive ventilation when the conventional oxygen therapy fails?

From Mindray 15 Apr 2020

Translating COVID-19 into sound

News-Medical speaks to Professor Markus Buehler about his research into COVID-19 and how he has translated the SARS-CoV-2 virus into sound.

14 Apr 2020

Predicting the evolution of genetic mutations

Biologists have developed an algorithm able to predict how genetic mutations can make critical proteins change with evolution.

14 Apr 2020

Mutated ATP1B gene a risk factor for Parkinson’s

The brain consists of about 100 billion neurons that form a complex and interconnected network in our brain, allowing us to generate complex thought patterns and actions. These neurons or nerve cells are the functional units of the nervous system that process and transmit information around the body. Neurodegenerative diseases develop with the progressive loss of these neurons.

14 Apr 2020

California COVID-19 herd immunity theory debunked

A recent theory suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was doing the rounds in California as early as November 2019, infecting thousands undetected and leading to herd immunity, was debunked by experts from the scientific community. Antibody testing by a group of Stanford Medicine researchers was linked to the theory.

14 Apr 2020

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway.

13 Apr 2020

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Disrupting production of sphingolipids in neurons improved neurodegeneration symptoms and increased survival in a mouse model.

13 Apr 2020

Researchers identify new risk gene for Parkinson's disease

Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.

12 Apr 2020