Genetic News and Research

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Removing a gene involved in repairing damaged DNA causes metabolic syndrome

Removing a gene involved in repairing damaged DNA causes mice to develop the metabolic syndrome, researchers at Oregon Health & Science University have discovered.

21 Feb 2006

MIT researchers capture virus in extraordinary detail

Fifty years after MIT researchers pioneered the use of electron microscopy to study viruses, MIT scientists have helped produce the most detailed images yet of the tiny infectious agents.

21 Feb 2006

Oddly shaped DNA can cause DNA breaks in mammalian cells

When otherwise normal DNA adopts an unusual shape called Z-DNA, it can lead to the kind of genetic instability associated with cancers such as leukemia and lymphoma, according to a study by researchers at The University of Texas M. D. Anderson Cancer Center.

21 Feb 2006

Effects of cancer treatment among children of survivors

Can the high doses of chemotherapy and radiation that young cancer patients receive cause inherited health problems for their children? Vanderbilt-Ingram Cancer Center member, John Boice, Sc.D., and an international team of colleagues have just been awarded a $4 million grant from the National Cancer Institute to try to find out.

21 Feb 2006

Lifetime calorie restraint to prevent obesity is the most powerful way to reduce age-related health problems

University of South Florida researcher Barbara Hansen, PhD, will likely never be invited to talk about weight loss on Oprah. Her message is mundanely common sense, not faddish - she doesn't drop phrases like "low carb," or "low fat," or "geared to your body type" or "put your body into fat-burning mode."

20 Feb 2006

Researchers create animal model of any schizophrenic characteristics

Researchers have developed a mouse strain in which the abnormal activity of the dopamine machinery in a specific part of the brain causes cognitive and behavioral impairments mimicking those in human schizophrenics.

20 Feb 2006

Mystery of evolutionary growth in hominid brain size

Forget the textbook story about tool use and language sparking the dramatic evolutionary growth of the human brain. Instead, imagine ancient hominid children chasing frogs. Not for fun, but for food.

19 Feb 2006

Ernst Mayr's theory illustrated in genetic epidemiology studies

The late, famed evolutionary biologist Ernst Mayr's theory of genetic revolution , introduced in 1954, remains controversial to this day and has many detractors.

19 Feb 2006

Pig islets successfully reversed diabetes in monkeys

Researchers at the University of Minnesota's Diabetes Institute for Immunology and Transplantation have successfully reversed diabetes in monkeys using transplanted islet cells from pigs.

19 Feb 2006

Bathroom scale model of weight loss most effective

According to a researcher in the U.S. losing and keeping off weight requires a lifelong commitment and effort.

19 Feb 2006

GeneDesign speeds design of artificial pieces of DNA

Johns Hopkins researchers have announced the development of a Web-based, automated computer program that they say greatly simplifies the time-consuming and error-prone process of manually designing artificial pieces of DNA.

17 Feb 2006

Inactivating Rad9 protien could make cancer cells easier to kill with ionizing radiation

The researchers found that Rad9, previously considered a "watchman" that checks for DNA damage, is actually a "repairman" that fixes dangerous breaks in the DNA double helix. They found Rad9 is especially active in telomeres, the protective ends of chromosomes.

17 Feb 2006

Farnesyltransferase inhibitor may improve progeria

UCLA researchers found that an experimental cancer drug improves the signs of progeria in a mouse model. Progeria is a rare genetic disease causing accelerated aging and cardiovascular disease in children. The new UCLA findings help to define a new strategy for treating children with progeria.

17 Feb 2006

Major Alzheimer's discovery

A team from the Faculty of Medicine at Universiti Laval and the research centre at CHUQ (Centre hospitalier universitaire de Quibec) has discovered a natural defence mechanism that the body deploys to combat nerve cell degeneration observed in persons with Alzheimer's disease (AD).

17 Feb 2006

Genome data may contain small but significant errors

Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been elucidated

17 Feb 2006

Science is bypassing poor people

Applying science and technology to build a Pluto-bound spacecraft that travels more than 10 times faster -- 47,000 miles per hour -- than a speeding bullet is a great achievement. But can we apply technology to feed the 800 million hungry people in the world whose plight isn't improving in a modern world?

17 Feb 2006

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006

Advancing knowledge of diet-gene interactions

Josi Ordovas, PhD, director of the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University joined more than eighty other leading researchers in the fields of nutrition and genetics to co-author a report outlining their strategy for maximizing the impact of nutrigenomics research on global poverty and health.

16 Feb 2006

Reading problems and behavior problems in boys are intertwined

It's been known for more than a decade that children with reading problems, particularly boys, also tend to have behavior problems, and vice versa. The reason behind the connection, however, remained unclear.

16 Feb 2006

Hormone aldosterone linked to quality of hearing

Researchers have linked a hormone known to adjust levels of key brain chemicals to the quality of our hearing as we age. The more of the hormone that older people have in their bloodstream, the better their hearing is, and the less of the hormone, the worse their hearing is.

16 Feb 2006