Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Mount Sinai researchers have discovered that a particular type of cell present in bladder cancer may be the reason why so many patients do not respond to the groundbreaking class of drugs known as PD-1 and PD-L1 immune checkpoint inhibitors, which enable the immune system to attack tumors.

29 Aug 2018

Study reveals how gene variant affects chronic pain outcomes after trauma

The gene FKBP5 is a critical regulator of the stress response and affects how we respond to environmental stimuli. Previous studies have shown that certain variants of this gene play a role in the development of neuropsychiatric disorders such as posttraumatic stress disorder, depression, suicide risk, and aggressive behavior.

28 Aug 2018

Restricting consumption of high-sucrose diet to active part of day avoids adverse effects in rats

A sedentary lifestyle combined with a diet dominated by processed foods has widely resulted in a range of conditions including diabetes, obesity, and high blood pressure, which are known collectively as metabolic syndrome.

27 Aug 2018

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Inhibition of miR-24-3p reduced growth of cancer cells and was found to regulate proteins as a potential treatment target for Mesothelioma.

25 Aug 2018

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

Sleep loss can confer increased risk of adverse weight gain, shows study

In a new study, researchers at Uppsala University now demonstrate that one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans.

23 Aug 2018

Scientists discover new genetic material that may regulate regeneration

Scientists at the MDI Biological Laboratory and the University of Maine have discovered that genetic material in the cell that was previously thought to be "junk" because of its apparent lack of function likely plays a part in regulating genetic circuits responsible for regeneration in highly regenerative animals.

22 Aug 2018

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Researchers at Lund University in Sweden have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease.

21 Aug 2018

Study uncover metabolic network controlled by the ‘circadian clock’ of muscle cells

How do muscle cells prepare for the particular metabolic challenges of the day? Scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München, members of the German Center for Diabetes Research, have investigated this question and published their results in 'PLOS Biology'.

21 Aug 2018

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers at the New York Genome Center and Columbia University have uncovered a molecular mechanism behind one of biology's long-standing mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease.

20 Aug 2018

Researchers develop gene expression predictor for immunotherapy response in melanoma

In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy.

20 Aug 2018

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

ALS -- amyotrophic lateral sclerosis -- is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow.

20 Aug 2018

New integrated gene logic-chips could have great value in medical care

Gene expression is a fundamental of life, where each cell switches on and off specific genes. Thus, an autonomous device that could control the on-off switching would have great value in medical care.

20 Aug 2018

Understanding How Antibodies Shape the Gut Microbiome

Dr. Keiichiro Suzuki discusses the importance of IgA in the human body, and his recent research study, which showed that IgA interacts with the gut microbiome and promotes the growth of healthy bacteria.

20 Aug 2018

Bacterial activity in child's mouth may serve as biomarkers for autism spectrum disorder

New research suggests that shifts in the bacteria within a child's mouth could provide objective biomarkers for identifying autism spectrum disorder.

17 Aug 2018

Lowering pH inside tumor cells can slow down spread of cancer

A new study focusing on the environment inside cancer cells may lead to new targeted treatment strategies.

17 Aug 2018

Researchers focus on uncoupling obesity from diabetes

About 422 million people around the world, including more than 30 million Americans, have diabetes. Approximately ninety percent of them have type 2 diabetes. People with this condition cannot effectively use insulin, a hormone made by the pancreas that helps the body turn blood sugar into energy.

15 Aug 2018

Gene Expression News and Research

Further Reading

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Study reveals how gene variant affects chronic pain outcomes after trauma

Restricting consumption of high-sucrose diet to active part of day avoids adverse effects in rats

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

Sleep loss can confer increased risk of adverse weight gain, shows study

Scientists discover new genetic material that may regulate regeneration

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Study uncover metabolic network controlled by the ‘circadian clock’ of muscle cells

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers develop gene expression predictor for immunotherapy response in melanoma

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

New integrated gene logic-chips could have great value in medical care

Understanding How Antibodies Shape the Gut Microbiome

Bacterial activity in child's mouth may serve as biomarkers for autism spectrum disorder

Lowering pH inside tumor cells can slow down spread of cancer

Researchers focus on uncoupling obesity from diabetes

Scientists reveal role of 'junk DNA' in cancer dissemination

Study reveals how immune cells in the brain influence sexual behavior

Scientists discover key vulnerability of mixed lineage leukemia

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