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Study: Bangladesh’s surface waters have high levels of antibiotic residues, chemicals

High levels of antibiotic residues, other medicines and chemicals present in Bangladesh's ponds, canals, lakes, rivers and other surface waters are contributing to a spike in antibiotic resistance in the country, says a new study.

11 Apr 2020

Combination of rare, damaging mutations negatively affects healthspan and longevity

Scientists report that the combined effects of rare, damaging mutations present at birth have a negative impact on healthspan and longevity, according to a study published this week in eLife.

9 Apr 2020

Phylogenetic network analysis provides ‘snapshot’ of COVID-19 origins

Researchers from Cambridge, UK, and Germany have reconstructed the early "evolutionary paths" of COVID-19 in humans - as infection spread from Wuhan out to Europe and North America - using genetic network techniques.

9 Apr 2020

Cancer-causing mutation also promotes inflammation

Analyses of cell signals provide insight into the origin of severe inflammatory symptoms that appear in various types of blood cancer and point to possible therapeutic approaches: In around one-fourth of patients suffering from juvenile myelomonocytic leukemia, there is evidence of mutations in the so-called KRAS gene in the leukemia cells.

8 Apr 2020

Analysis of causative protein genotype can help predict Alport syndrome severity

A Japanese research team has successfully developed a system to predict the severity of Alport syndrome, a serious hereditary kidney disease that occurs in about 1 out of 5,000 people in the US. Patients with Alport syndrome have abnormalities in the causative protein, type IV collagen, that often lead to chronic renal dysfunction requiring dialysis.

6 Apr 2020

Natural approaches along with current therapies could improve colon cancer treatment

Using a modified natural substance along with current approaches could improve colon cancer treatment, according to findings by University of California, Irvine biologists.

6 Apr 2020

Researchers uncover genetic mutation responsible for aggressive head and neck, lung cancers

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have uncovered a genetic variant in a gene called MET that is responsible for more aggressive growth of head and neck, and lung cancers.

6 Apr 2020

Immunotherapy prior to surgery is effective in colon cancer

Patients with colon cancer, but no distant metastases, can benefit from immunotherapy while waiting for surgery.

6 Apr 2020

Research suggests an avenue to treat, prevent genetic disorders in the womb

New research led by hearing scientists at Oregon Health & Science University suggests an avenue to treat and prevent intractable genetic disorders before birth.

6 Apr 2020

Scientists examine the molecular causes of rare hereditary disease

Scientists in EMBL Barcelona’s Ebisuya group, with collaborators from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, have studied oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro, to explore the molecular causes of a rare human hereditary disease known as spondylocostal dysostosis.

5 Apr 2020

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

5 Apr 2020

First genome sequences of SARS-CoV-2 viruses in Austria openly available

The first 21 SARS-CoV-2 genomes in Austria have now been completed and published within the scope of the “Mutational Dynamics of SARS-CoV-2” project recently launched by CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, in close collaboration with the Medical University of Vienna.

3 Apr 2020

COVID-19 by the numbers

Numerical data sometimes reveal facts that are otherwise concealed within an onslaught of information from an overwhelming number of sources.

2 Apr 2020

Can cats and dogs catch or spread COVID-19?

A recent report from Hong Kong that two dogs had tested positive for the novel coronavirus SARS-CoV-2 had pet owners in a tizzy. This was compounded by news that a cat owned by a COVID-19 patient had developed symptoms of the illness in Belgium – such as breathing trouble and diarrhea – a week after the owner tested positive. The cat’s vomit and feces were subsequently found to be positive for the viral genome.

2 Apr 2020

New study offers clues to why autism is more common in boys than in girls

A new study in Neuron offers clues to why autism spectrum disorder is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases.

2 Apr 2020

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit.

1 Apr 2020

Putting an end to the pandemic

From the plagues of medieval Europe to the influenza pandemic of 1918, the specter of the next public health disaster has gripped the minds of scientists, captivated the imaginations of writers and vexed conspiracy theorists.

1 Apr 2020

Immunotherapy may benefit mCRPC patients with specific markers of immune activation

Although metastatic castration-resistant prostate cancer typically has limited response to immunotherapy, a subset of patients with pretreatment evidence of active T-cell responses in their tumors experienced prolonged survival following treatment with ipilimumab in a Phase II trial at The University of Texas MD Anderson Cancer Center.

1 Apr 2020

Researchers identify risk gene for Alzheimer's development

Researchers from the University of British Columbia and the Central South University in China have for the first time identified a gene that increases the risk of Alzheimer's disease.

1 Apr 2020

Inherited gene mutation can predispose children to SHH medulloblastoma

Investigators at St. Jude Children's Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup of pediatric medulloblastoma.

1 Apr 2020

Mutation News and Research

Study: Bangladesh’s surface waters have high levels of antibiotic residues, chemicals

Combination of rare, damaging mutations negatively affects healthspan and longevity

Phylogenetic network analysis provides ‘snapshot’ of COVID-19 origins

Cancer-causing mutation also promotes inflammation

Analysis of causative protein genotype can help predict Alport syndrome severity

Natural approaches along with current therapies could improve colon cancer treatment

Researchers uncover genetic mutation responsible for aggressive head and neck, lung cancers

Immunotherapy prior to surgery is effective in colon cancer

Research suggests an avenue to treat, prevent genetic disorders in the womb

Scientists examine the molecular causes of rare hereditary disease

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

First genome sequences of SARS-CoV-2 viruses in Austria openly available

COVID-19 by the numbers

Can cats and dogs catch or spread COVID-19?

New study offers clues to why autism is more common in boys than in girls

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

Putting an end to the pandemic

Immunotherapy may benefit mCRPC patients with specific markers of immune activation

Researchers identify risk gene for Alzheimer's development

Inherited gene mutation can predispose children to SHH medulloblastoma

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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