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New HIV therapy lenacapavir shows high efficacy in Ugandan population

A multi-national, multi-institutional study led by Weill Cornell Medicine investigators found little natural resistance to a new HIV therapy called lenacapavir in a population of patients in Uganda.

19 Feb 2025

Hydrodissection may offer hope for post-amputation pain relief

A reliable method to treat post-amputation pain remains elusive, but a new Northwestern Medicine study conducted in collaboration with Ukrainian physicians suggests that hydrodissection - a simple procedure that injects fluid around nerves - may reduce residual limb pain and opioid dependence.

19 Feb 2025

New mRNA technique targets disease cells while sparing healthy ones

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

19 Feb 2025

Republicans are eyeing cuts to Medicaid. What’s Medicaid, again?

In January, during a congressional hearing on his way to becoming secretary of the Department of Health and Human Services, Robert F. Kennedy Jr. got basic details wrong about Medicaid — a program he now oversees.

19 Feb 2025

Nerinetide shows promise in stroke treatment meta-analysis

The Calgary Stroke Program, a joint University of Calgary and Alberta Health Services initiative at Foothills Medical Centre, has been involved with three papers published this week in The Lancet and Lancet Neurology-the ESCAPE-NEXT trial, the FRONTIER trial, and an individual patient-level meta-analysis across three trials.

19 Feb 2025

New treatment cuts aggression in male offenders with antisocial personality disorder

A new psychological therapy designed by a team of UCL-led researchers has been found to reduce rates of violence and aggression among male offenders with antisocial personality disorder (ASPD).

18 Feb 2025

Study reveals key genetic clues for prostate cancer progression

A recent study published in the Journal of Cancer Research and Clinical Oncology explored genetic predictors of prostate cancer progression to help identify its clinical outcomes.

18 Feb 2025

New drug mimics low-oxygen treatment for Leigh Syndrome

For the average person, living at high altitude-where oxygen is sparser than at sea level-can have health benefits ranging from lower rates of heart disease to increased endurance.

18 Feb 2025

Researchers develop mouse model to study neutrophilic asthma

A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for asthma, including biologic therapies.

18 Feb 2025

Study highlights risks of stopping anticoagulants in older patients

For patients with atrial fibrillation, the risk of stroke or heart attack from stopping anticoagulants usually outweighs the risk of bleeding, according to new findings from the University of Bath.

18 Feb 2025

Senolytic agent ABT-263 mitigates GI cancer risk after radiation exposure

A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, titled "Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice."

18 Feb 2025

Fungal component may protect against flu-related lung damage

A component found in all fungi may provide a shield against flu-related lung damage, according to a new study.

18 Feb 2025

Swimming in lakes may increase risk of Legionella infection

Swimming in some lakes with still water can lead to infection with Legionella, bacteria that can cause pneumonia, and people who engage in open water swimming should be aware of this risk, say the authors of a practice article published in CMAJ.

18 Feb 2025

Gene therapy breakthrough offers hope for severe Dravet syndrome cases

AAV-Navβ1 gene therapy effectively reduces seizures and prolongs life in a mouse model of SCN1B-linked Dravet syndrome, paving the way for future treatments.

18 Feb 2025

Cancer-free for 18 years: CAR-T therapy sets new milestone in neuroblastoma treatment

A groundbreaking study in Nature Medicine reveals that GD2 CAR-T cell therapy can lead to long-term remission in children with neuroblastoma, with one patient remaining cancer-free for over 18 years.

17 Feb 2025

Sweat fails to match blood in tracking inflammation after heart attacks

Researchers found that while sweat biomarkers remain stable, plasma biomarkers show significant inflammatory changes after a heart attack, highlighting the limitations of sweat analysis for tracking recovery.

17 Feb 2025

NIDUS-Family care package reduces dementia support costs

The NIDUS-Family package of care uses goal setting to help people with dementia live well at home for longer.

17 Feb 2025

Lecanemab and donanemab slow Alzheimer’s decline, but is the benefit worth the cost?

Study finds that disease-modifying therapies for Alzheimer’s, lecanemab and donanemab, can extend independence in daily activities by up to 13 months, though their clinical relevance remains debated.

17 Feb 2025

Diabetes fuels antibiotic resistance, worsening infections and treatment challenges

A new study reveals that diabetes significantly accelerates the emergence and spread of antibiotic-resistant Staphylococcus aureus infections, highlighting a major public health concern.

17 Feb 2025

AI tool speeds up patient screening for heart failure trials

Artificial intelligence (AI) can rapidly screen patients for clinical trial enrollment, according to a new study published in JAMA and led by Mass General Brigham researchers.

17 Feb 2025