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Study elucidates importation risks and disproportionate spread of SARS-CoV-2 variants of concern in the Netherlands

Researchers used whole-genome sequencing to explore the transmission dynamics of four SARS-CoV-2 variants of concern - Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2) in the Netherlands.

24 Mar 2022

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

Study uncovers a gene that strongly associates with breast cancer patient's treatment outcomes

A multidisciplinary team of researchers from Roswell Park Comprehensive Cancer Center and Kaiser Permanente Northern California have identified the first pharmacogenomic marker for anthracyclines and HER2-targeting drugs, two commonly used breast cancer chemotherapies.

23 Mar 2022

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Scientists from the United States have recently assessed the evolutionary success of mutations accumulated across severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. They have observed that the positively-selected mutations in the viral spike S1 subunit are primarily responsible for adaptive evolution. This indicates that the virus may undergo antigenic drift.

23 Mar 2022

Predicting the risk of some common diseases in preimplantation fertilized embryos

A new study uses a novel strategy for whole-genome reconstruction by using parental genome sequencing and sibling embryo genotyping.

23 Mar 2022

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

There is likely recombination of genome sequences between the SARS-CoV-2 Delta and Omicron variants in their spike (S) protein.

23 Mar 2022

SARS-CoV-2 mRNA vaccines may prevent COVID-19-associated mechanical ventilation and death

Researchers performed a case-control study to evaluate the effectiveness of SARS-CoV-2 messenger ribonucleic acid vaccines.

23 Mar 2022

Researchers find two gene variants linked to accelerated aging in childhood cancer survivors

Scientists from St. Jude Children's Research Hospital have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors. Their research looked at the difference between their biological age and chronological age.

23 Mar 2022

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

23 Mar 2022

The relative performance of OPS, NPS, and saliva for detecting the Delta and Omicron SARS-CoV-2 variants

Scientists have worked extensively hard to contain the COVID-19 pandemic caused by the rapid transmission of SARS-CoV-2.

22 Mar 2022

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

In a world-first, scientists from BGI-Research, Chinese Academy of Sciences, and a group of partners published a study in Nature, announcing the discovery of a transgene-free, rapid, and controllable method to convert pluripotent stem-cells into bona fide 8-cell totipotent embryo-like cells, paving the way for advances in organ regeneration and synthetic biology.

22 Mar 2022

Genome News and Research

Study elucidates importation risks and disproportionate spread of SARS-CoV-2 variants of concern in the Netherlands

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

Study uncovers a gene that strongly associates with breast cancer patient's treatment outcomes

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Predicting the risk of some common diseases in preimplantation fertilized embryos

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

SARS-CoV-2 mRNA vaccines may prevent COVID-19-associated mechanical ventilation and death

Researchers find two gene variants linked to accelerated aging in childhood cancer survivors

Scientists identify a promising strategy for stopping Ebola virus polymerase

The relative performance of OPS, NPS, and saliva for detecting the Delta and Omicron SARS-CoV-2 variants

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Study explores minimal classroom transmission of COVID-19 in a large urban university

Using CRISPR/Cas to develop biosafety materials

AI system can help detect the degree and severity of heart transplant rejection

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

Clinical severity of SARS-CoV-2-Omicron infection found to be lower than Delta infection

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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