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Support for enteric nervous system pathology in prodromal PD

Researchers have found positive immunostaining of α-synuclein in the enteric nervous system of patients with idiopathic rapid eye movement sleep behaviour disorder, suggesting it may have a possible role as a biomarker for prodromal Parkinson’s disease.

22 Oct 2015

Confocal microscope designed specifically for scientists launched by Caliber ID

Caliber Imaging & Diagnostics, Inc. (Caliber I.D.), an Andover, MA-based medical technologies company with more than 20 years of experience in the design and development of innovative imaging solutions for the examination of tissue at the cellular level, has introduced its first confocal microscope exclusively for the research scientist, the RS-G4.

21 Oct 2015

Study shows why cancer anemia therapy stimulates tumor growth

Scientists have shown why a drug widely used to treat chemotherapy-induced anemia in ovarian and breast cancer patients also may shorten survival times in some patients by inadvertently stimulating tumor growth.

16 Oct 2015

Native Antigen Co. announces the launch of a new range of Dengue Virus-Like Particles

Virus-Like Particles (VLPs) represent an increasingly important technology for use in vaccine development and serology. VLPs consist of protein shells comprising outer proteins specific to the virus in question.

16 Oct 2015

Researchers report weak association between brain size and IQ

As early as 1836, the German physiologist and anatomist Friedrich Tiedemann, in an article in the Philosophical Transactions, expressed his opinion that "there is undoubtedly a connection between the absolute size of the brain and the intellectual powers and functions of the mind". With the advent of brain imaging methods (e.g., MRI, PET), reliable assessments of in-vivo brain volume and investigations of its association with IQ are now possible.

15 Oct 2015

Drug interactions in placenta may increase risk of birth defects or stunting fetal growth

To date, studies in pregnant women examining transport of drugs across the placenta are rare and inadequate, said Tomo Nabekura, PhD. Such knowledge could be vital to preserving fetal health. In a new laboratory study, Nabekura and colleagues have illuminated a piece of this puzzle, and the results hint that mothers taking new anti-hepatitis C and/or anti-HIV drugs along with anti-hypertensives or non-steroidal anti-inflammatories (NSAIDs) could be raising the risk of birth defects or stunting fetal growth, respectively.

15 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

VTT examines effectiveness of beauty patch using unique imaging technology

VTT Technical Research Centre of Finland has analysed the effectiveness of its beauty patch, using a technique for imaging live tissue to demonstrate the patch's beneficial effects on the skin. Preliminary results show that already after two weeks usage the patch together with cosmetic serum adds collagen, which helps skin tissue to stay supple.

14 Oct 2015

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Researchers at the University of Washington have used a noninvasive light-based imaging technology to literally see inside the living brain, providing a new tool to study how diseases like dementia, Alzheimer's, and brain tumors change brain tissue over time.

13 Oct 2015

Glycan binding proteins modify parasite infection in cells of the heart muscle

Chagas disease is the main cause of infectious heart disease in Latin America. Researchers from the INGEBI and IBYME Institutes in Argentina explored the effect of glycan binding protein interactions between the human host and Typanosoma cruzi parasite. They found that a glycan binding protein expressed in humans modified the infection in cells of the heart muscle, showing the importance of galectins in the response to parasite infection.

12 Oct 2015

Artificial lung model could provide better understanding of health risks associated with airborne pollution

A life-sized artificial human lung created at the Technion-Israel Institute of Technology is the first diagnostic tool for understanding in real time how tiny particles move and behave in the deepest part of the human lungs (alveolar tissue).

9 Oct 2015

Michigan researchers use Raman spectroscopy to study various childhood diseases

Renishaw, a world leader in metrology and spectroscopy, reports on the use of its inVia confocal Raman microscope in the study of various diseases–with a major focus on childhood diseases–at the Children's Hospital of Michigan and Wayne State University.

6 Oct 2015

Novel prosthetic heart valve developed for treatment of mitral regurgitation

A team of researchers from the National University of Singapore (NUS) has developed a novel prosthetic heart valve, known as VeloX, which can be implanted through a small incision for the treatment of a serious heart valve disorder called mitral regurgitation. This is a condition in which the mitral valve on the left side of the heart does not close properly. The device is particularly beneficial to patients who are of high surgical risk or are unsuitable for existing clinical interventions.

6 Oct 2015

Leading cancer researchers address eight 'big questions'

Leading cancer researchers address eight of the "big questions" facing the field as part of the inaugural issue of Trends in Cancer, published by Cell Press.

30 Sep 2015

Glowing protein may replace fiber optic cable as light source in optogenetics research

Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the brain conveniently in animals, activating or inhibiting selected groups of neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the brain.

30 Sep 2015

MedUni Vienna researchers report new strategy for targeted treatment of ovarian cancer

A team of researchers at the MedUni Vienna has confirmed in a recent study its new concept for the targeted treatment of ovarian cancer. The concept is intended to better control the development of resistance and improve treatment outcomes.

29 Sep 2015

Research posters support utility of EKF’s PointMan DNA enrichment technology for rapid detection of lung cancer mutations

EKF, announces two research posters supporting application of PointMan™ DNA enrichment technology, for rapid and sensitive detection of lung cancer mutations.

From EKF Diagnostics 29 Sep 2015

in vivo News and Research

Support for enteric nervous system pathology in prodromal PD

Confocal microscope designed specifically for scientists launched by Caliber ID

Study shows why cancer anemia therapy stimulates tumor growth

Native Antigen Co. announces the launch of a new range of Dengue Virus-Like Particles

Researchers report weak association between brain size and IQ

Drug interactions in placenta may increase risk of birth defects or stunting fetal growth

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

VTT examines effectiveness of beauty patch using unique imaging technology

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Glycan binding proteins modify parasite infection in cells of the heart muscle

Artificial lung model could provide better understanding of health risks associated with airborne pollution

Michigan researchers use Raman spectroscopy to study various childhood diseases

Novel prosthetic heart valve developed for treatment of mitral regurgitation

Leading cancer researchers address eight 'big questions'

Glowing protein may replace fiber optic cable as light source in optogenetics research

MedUni Vienna researchers report new strategy for targeted treatment of ovarian cancer

Research posters support utility of EKF’s PointMan DNA enrichment technology for rapid detection of lung cancer mutations

Philip Chapper & Co to showcase new partner products at Europe’s largest pharmaceutical trade fair

Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

Protein-coding gene identified as tumor suppressor for acute myeloid leukemia

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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