Genetic News and Research

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Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Discovery of a potential oncogene in ovarian cancer

Researchers at The University of Texas M. D. Anderson Cancer Center report they have discovered a potential oncogene in ovarian cancer, which is the leading cause of gynecological cancer death in U.S. women.

22 Aug 2005

Scientists step closer to understanding the genetic pathway involved in the development of hearing

New research findings, published online in the journal Nature Genetics, detail how sensory hair cells in the ear - the cells largely responsible for hearing - develop unique shapes that enable the perception of sound.

22 Aug 2005

Heat stress and injury among young athletes can be prevented by progressively increasing practice time and replacing lost fluids

Progressively increasing practice time and intensity and ensuring that football players are replacing lost fluids during training are two ways to significantly reduce the risk of heat stress and injury during preseason practice, a recent expert panel convened by the American College of Sports Medicine found.

22 Aug 2005

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

The scientists found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the disease whose protein has a known function.

22 Aug 2005

Discovery of new gene FANCM sheds light on repair of damaged DNA

National Institute on Aging (NIA) researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA.

22 Aug 2005

High rate of heart attack amongst ethnic minorities in Scotland

The incidence of heart attack amongst Scots of Indian and Pakistani origin is 60-70% higher when compared with non-South Asians, a new report led by the University of Edinburgh has shown.

18 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

C. elegans has similar virus-fighting mechanism as humans and can be used in research

Researchers at the University of California, Riverside have discovered that a simple worm, called C. elegans, makes an excellent experimental host for studying some of the most virulent viruses that infect humans.

17 Aug 2005

Loss of a gene called p63 accelerates aging in mice

Researchers have discovered that the loss of a gene called p63 accelerates aging in mice. Similar versions of the gene are present in many organisms, including humans. Therefore, the p63 gene is likely to play a fundamental biological role in aging-related processes.

17 Aug 2005

Researchers have discovered a gene linked to age-related maculopathy

University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly. Their discovery suggests a simple test might be able to identify those at risk for what is commonly known as macular degeneration (AMD) and may lead to the development of more effective preventive strategies.

16 Aug 2005

Developmental culling and cancer

A new study reveals that a diverse group of apparently unrelated genes that are associated with pheochromocytoma intersect at a common pathway that drives the necessary culling of cells.

16 Aug 2005

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome.

15 Aug 2005

Lung cancer cure possible with early screening

Recent reports in the media of the deaths of well known people from lung cancer and the surprising news that Dana Reeve, the non-smoking wife of the late Christopher Reeve has the disease, has re-ignited concerns about the so-called 'silent killer', lung cancer.

15 Aug 2005

Calcium fights prostate cancer

Calcium, more familiar in its role as one of the building blocks of the body, is being enlisted as a tool in the fight against prostate cancer.

15 Aug 2005

Combined gene therapy eliminates glioblastoma multiforme in lab studies

Despite aggressive treatment, glioblastoma multiforme (GBM) - the most common and deadly of brain cancers - usually claims the lives of its victims within six to 12 months of diagnosis. Because GBM is so aggressive, the disease has been the target of a number of laboratory and clinical studies investigating the effectiveness of gene therapy to deliver novel therapies to the brain.

15 Aug 2005

DNA chip technology helps with discovery of new type 2 diabetes gene

In a new study appearing in the August 12 issue of the journal Cell, the investigators first identified genes that were altered in their level of expression in islets isolated from people with type 2 diabetes.

13 Aug 2005

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

A collaborative project between American and Chinese researchers developed a way to study the function of genes in mice and man by using a moveable genetic element from moths, according to a report in the journal Cell.

13 Aug 2005

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine.

13 Aug 2005

Genetic News and Research

Gene therapy advance shows potential for developing improved treatment for hemophilia

Discovery of a potential oncogene in ovarian cancer

Scientists step closer to understanding the genetic pathway involved in the development of hearing

Heat stress and injury among young athletes can be prevented by progressively increasing practice time and replacing lost fluids

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

Discovery of new gene FANCM sheds light on repair of damaged DNA

High rate of heart attack amongst ethnic minorities in Scotland

Protein Sirt1 points to new therapies for type 2 diabetes

Defects in newly discovered pathway may be an overlooked cause of anemia

C. elegans has similar virus-fighting mechanism as humans and can be used in research

Loss of a gene called p63 accelerates aging in mice

Researchers have discovered a gene linked to age-related maculopathy

Developmental culling and cancer

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Lung cancer cure possible with early screening

Calcium fights prostate cancer

Combined gene therapy eliminates glioblastoma multiforme in lab studies

DNA chip technology helps with discovery of new type 2 diabetes gene

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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