Genomic News and Research

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Novel device may help restore total eye function

An international consortium of researchers is developing a new method to bring eyes back to life from deceased body donors for clinical research purposes.

18 Dec 2020

Discovery of protein function could be important for future chemotherapy treatment

Chemotherapy attacks all cells in our body and not just cancer cells, which is why patients undergoing the treatment often experience side effects such as physical weakness, hair loss and nausea.

17 Dec 2020

Specific genetic target could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Oral hormone therapy significantly alters the metabolome of postmenopausal women

Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women.

16 Dec 2020

A new approach to identify genomic regions in our brain that contribute to make us human

With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar.

16 Dec 2020

SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

A new study reveals that the genome of SARS-CoV-2 is inserted into the human genome, accounting for the detection of viral RNAs.

16 Dec 2020

SARS-CoV-2 unique deletion variants found in clinical specimens

While participating in the SPHERES Consortium project, US researchers sequenced 2,726 clinical patient specimens gathered in March 2020 and identified eight unique ORF7a deletion variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their results are currently available on the bioRxiv* preprint server.

15 Dec 2020

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Prostate cancer is one of the most common cancers among men in the United States. One in nine men will be diagnosed during his lifetime.

15 Dec 2020

FDA approves first IGA in GalSafe pigs for human food, promising therapeutic uses

Today, the U.S. Food and Drug Administration approved a first-of-its-kind intentional genomic alteration (IGA) in a line of domestic pigs, referred to as GalSafe pigs, which may be used for food or human therapeutics.

15 Dec 2020

Children with cancer do not appear to be at increased risk of severe COVID-19 infection

Results from the first national study of children with cancer who test positive from COVID-19 has found that these patients do not appear to be at any increased risk of severe COVID-19 infection compared to healthy children.

14 Dec 2020

Extensive genomic data can improve breast cancer risk assessment

Findings from the FinnGen study encompassing 120,000 women indicate that inherited breast cancer risk should be assessed in an increasingly comprehensive manner.

14 Dec 2020

Emergence of resistant SARS-CoV-2 variant in immunocompromised patient following therapeutic antibody use

The focus is increasingly moving towards vaccine roll-out as the world faces the real possibility of the second year of social and economic restrictions.

14 Dec 2020

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

Scientists have suggested that a proportion of the population have pre-existing immunity to COVID-19 because of T cells primed against SARS-CoV-2 antigens.

14 Dec 2020

D614G mutation promotes lysosomal trafficking of SARS-CoV-2 spike protein

In the current COVID-19 pandemic, SARS-CoV-2 has led to millions of infections worldwide, with over 1.5 million deaths.

14 Dec 2020

RNA editing within host linked to SARS-CoV-2 variants

Since the start of the COVID-19 pandemic, the causative virus, SARS-CoV-2, has undergone several mutations.

14 Dec 2020

Scientists get closer to finding the genes for maleness in weeds

Scientists are getting closer to finding the genes for maleness in waterhemp and Palmer amaranth, two of the most troublesome agricultural weeds in the U.S.

11 Dec 2020

Study shows how coronavirus uses spike proteins to infiltrate cells of different animals

Humans, followed by ferrets and to a lesser extent cats, civets and dogs are the most susceptible animals to SARS-CoV-2 infection, according to an analysis of ten different species carried out by researchers at the Centre for Genomic Regulation (CRG), based in Barcelona.

11 Dec 2020

Data confirms early cases of SARS-CoV-2 in Boston area

SARS-CoV-2 was introduced to the Boston area of Massachusetts many times in early 2020, according to a new analysis of virus genomes, but only a small number of importations - including one related to an international business conference - led to most cases there.

11 Dec 2020

IGC researchers receive three out of six European Research Council grants

Since the establishment of the European Research Council in 2008, the IGC has secured 17 of their competitive grants (7 Starting, 8 Consolidator and 2 Advanced).

10 Dec 2020

Hematoxylin compounds can selectively kill CALR mutant cancer cells

Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR).

10 Dec 2020

Genomic News and Research

Novel device may help restore total eye function

Discovery of protein function could be important for future chemotherapy treatment

Specific genetic target could help explain the variation in COVID-19 effects

Oral hormone therapy significantly alters the metabolome of postmenopausal women

A new approach to identify genomic regions in our brain that contribute to make us human

SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

SARS-CoV-2 unique deletion variants found in clinical specimens

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

FDA approves first IGA in GalSafe pigs for human food, promising therapeutic uses

Children with cancer do not appear to be at increased risk of severe COVID-19 infection

Extensive genomic data can improve breast cancer risk assessment

Emergence of resistant SARS-CoV-2 variant in immunocompromised patient following therapeutic antibody use

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

D614G mutation promotes lysosomal trafficking of SARS-CoV-2 spike protein

RNA editing within host linked to SARS-CoV-2 variants

Scientists get closer to finding the genes for maleness in weeds

Study shows how coronavirus uses spike proteins to infiltrate cells of different animals

Data confirms early cases of SARS-CoV-2 in Boston area

IGC researchers receive three out of six European Research Council grants

Hematoxylin compounds can selectively kill CALR mutant cancer cells

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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