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Study could help develop new oral drugs for treating muscular dystrophy, heart failure

Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows.

12 Jan 2021

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences

In a recent bioRxiv preprint study, researchers from the University of Hawaii showed that the S gene of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating according to the sequence and phylogenetic analysis.

10 Jan 2021

New approach to tame botulinum toxin for drug delivery

While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known.

8 Jan 2021

Study finds lower degree of myocarditis in athletes with a history of COVID-19

In a letter published in the December issue of the American Heart Association's medical journal Circulation a group of researchers at Vanderbilt University Medical Center (VUMC) dispute the most recent findings of the incidence of myocarditis in athletes with a history of COVID-19.

8 Jan 2021

Study reveals six-month consequences of COVID-19 in patients discharged from hospital

More than three quarters of COVID-19 patients have at least one ongoing symptom six months after initially becoming unwell, according to research published in The Lancet.

8 Jan 2021

Potential role of chitinase 3-like-1 in severity of COVID-19

Now, an intriguing preprint research paper on the bioRxiv server reports the identification of an enzyme called chitinase 3-like-1 (CHI3L1) that mediates this age-dependent impact of the virus and could serve as a powerful therapeutic approach in mitigating the severity of COVID-19 in this high-risk group.

7 Jan 2021

Focused ultrasound shows potential to benefit people with Parkinson's disease

A scalpel-free alternative to brain surgery has the potential to benefit people with Parkinson's disease symptoms that are much more severe on one side of the body, new research suggests.

7 Jan 2021

Resistance training provides similar relative benefits to older men and women

Men and women aged over 50 can reap similar relative benefits from resistance training, a new study led by UNSW Sydney shows.

7 Jan 2021

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

New approach produces strong antidotal efficacy in treating lethal botulism in animals

Related to new research published in the January issue of Science Translational Medicine, Patrick McNutt, PhD, of the Wake Forest Institute for Regenerative Medicine, was part of the research team that demonstrated a new "Trojan horse" approach that produces strong antidotal efficacy in treating lethal botulism in mice, guinea pigs and rhesus macaque monkeys.

7 Jan 2021

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is thought to have a zoonotic origin, perhaps originating in a bat coronavirus with an unknown intermediate host. It is not only very infectious but has been found to infect a wide range of mammals, including dogs, cats, ferrets, hamsters, and minks, besides non-human primates. This range may be still higher, claims a recent preprint that appeared in January 2021 on the bioRxiv server.

6 Jan 2021

Study shows durable specific humoral immunity against SARS-CoV-2 after mild or asymptomatic infection

As a part of the COMMUNITY (COVID-19 Immunity) study, researchers from Sweden reveal long-lasting IgG neutralizing antibody response against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the vast majority of convalescent individuals – even after asymptomatic or mild infection. Their results are currently available on medRxiv* preprint server.

6 Jan 2021

First steps toward uncovering CRISPR/Cas gene doping in plasma

All athletes want to be at the top of their game when they compete, but some resort to nefarious approaches to achieve peak muscle growth, speed and agility. Recent developments in gene editing technology could tempt athletes to change their DNA to get an edge.

6 Jan 2021

Smokers at increased risk of developing symptomatic COVID-19

Smoking is associated with an increased risk of COVID-19 symptoms and smokers are more likely to attend hospital than non-smokers, a study has found.

6 Jan 2021

Cholesterol-lowering drugs may protect women's hearts from damage caused during chemotherapy

Statins, common cholesterol-lowering medications, may protect women's hearts from damage caused during chemotherapy for early-stage breast cancer, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

6 Jan 2021

Muscle News and Research

Study could help develop new oral drugs for treating muscular dystrophy, heart failure

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences

New approach to tame botulinum toxin for drug delivery

Study finds lower degree of myocarditis in athletes with a history of COVID-19

Study reveals six-month consequences of COVID-19 in patients discharged from hospital

Potential role of chitinase 3-like-1 in severity of COVID-19

Focused ultrasound shows potential to benefit people with Parkinson's disease

Resistance training provides similar relative benefits to older men and women

CytoDel successfully delivers neuronal antibody in animal models of botulism

New approach produces strong antidotal efficacy in treating lethal botulism in animals

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

Study shows durable specific humoral immunity against SARS-CoV-2 after mild or asymptomatic infection

First steps toward uncovering CRISPR/Cas gene doping in plasma

Smokers at increased risk of developing symptomatic COVID-19

Cholesterol-lowering drugs may protect women's hearts from damage caused during chemotherapy

Statins may protect the heart from damaging side-effects of early breast cancer treatment

Experts assess the impact of COVID-19 on pediatric patients with special needs

USF researchers discover promising new compound to open constricted airways

Study shows mRNA-1273 vaccine can prevent symptomatic COVID-19 infection

Phase 3 results show investigational vaccine is effective in preventing severe COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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