Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Researchers identify protein biomarker linked to prognosis in high-grade serous ovarian cancer

Ovarian cancer researchers have identified a protein biomarker expressed on the surface of tumour cells in high-grade serous ovarian cancer, the most common and lethal subtype of the disease.

7 Mar 2017

ESMO announces takeover of Targeted Anticancer Therapies Congress series

ESMO, the leading European organisation for medical oncology, has announced it will take over the organisation of the Targeted Anticancer Therapies Congress series, with the aim of expanding its educational offer and ensure that professionals are kept up to date with the latest drug developments to improve outcomes for cancer patients.

7 Mar 2017

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

In March 2016 Insilico Medicine initiated a research collaboration with Life Extension to apply advanced bioinformatic methods and deep learning algorithms to screen for naturally occurring compounds that may slow down or even reverse the cellular and molecular mechanisms of aging. Today Life Extension (LE) launched a new line of nutraceuticals called GEROPROTECTTM, and the first product in the series called Ageless CellTM combines some of the natural compounds that were shortlisted by Insilico Medicine’s algorithms and are generally recognized as safe (GRAS).

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Researchers have uncovered new genetic clues to understanding IgA nephropathy (IgAN), or Berger's disease, an autoimmune kidney disease and a common cause of kidney failure.

6 Mar 2017

Altered distribution of cerebrospinal fluid can predict autism risk in infants

Researchers from the UC Davis MIND Institute, University of North Carolina and other institutions have found that altered distribution of cerebrospinal fluid in high-risk infants can predict whether they will develop autism spectrum disorder.

6 Mar 2017

International consortium aims to improve therapeutic options for diabetes-induced kidney disease

Chronic kidney disease is a frequently encountered disorder: more than 10% of the population suffer from such problems.

3 Mar 2017

Michigan Medicine opens first clinic in the United States that focuses on prostate cancer risk

It's well known that women with certain hereditary genetic mutations, particularly BRCA1 and BRCA2, have an increased risk of breast cancer. But in recent years, researchers have discovered a link between some of those same genetic mutations - along with a handful of others - and aggressive prostate cancer.

3 Mar 2017

Medicaid expansion improves health, financial benefits for many low-income Ohioans

Ohio's 2014 Medicaid expansion improved health and financial benefits for hundreds of thousands of low-income Ohioans, according to an assessment supported by RTI International.

2 Mar 2017

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Adding two blood-borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

1 Mar 2017

Researchers identify genomic biomarker in nasal passage that can accurately detect lung cancer

A new nasal test may allow patients suspected of having lung cancer to undergo a simple swab of their nose to determine if they have the disease.

27 Feb 2017

New test could accelerate development of better treatments for Motor Neuron Disease

A cutting-edge test developed in South Australia has the potential to expedite the worldwide quest to develop better treatments, or even a cure, for the Motor Neuron Disease (MND).

24 Feb 2017

Researchers reveal biological pathways involved in diabetic kidney disease

Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages.

24 Feb 2017

Alterations in brain connectivity can aid diagnosis and prediction of outcomes in mTBI patients

A new study shows that patients with mild traumatic brain injury, even without evidence of brain lesions, may exhibit changes in brain connectivity detectable at the time of the injury that can aid in diagnosis and predicting the effects on cognitive and behavioral performance at 6 months.

23 Feb 2017

New clinical practice guideline addresses testing of molecular biomarkers in colorectal cancer patients

A new, evidenced-based clinical practice guideline on molecular biomarker testing for patients with colorectal cancer identifies opportunities for improving patient outcomes.

23 Feb 2017

Researchers find novel, non-invasive approach for diagnosis and prognosis of prostate cancer

In a new paper in Springer's Journal of Materials Science, researchers at Washington State University report a new approach for the effective capture of tumor-derived exosomes from a prostate cancer cell line.

21 Feb 2017

Cocaine addiction may disrupt iron regulation in the brain, study finds

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge.

21 Feb 2017

High levels of biomarker linked to poor prognosis in African-Americans with triple-negative breast cancer

Having high levels of a certain biomarker is linked to poor prognosis in African-American patients with triple-negative breast cancer, while the same biomarker doesn't influence disease outcomes in white patients, according to a new study.

21 Feb 2017

microDimensions launches new version of high precision whole slide alignment software

microDimensions launches a new version of its high precision whole slide alignment software Slidematch. With the new version users can align digital whole slide images from consecutive sections in brightfield and fluorescence mode, e.g. for the evaluation of the HER2 status of cancer patients.

From microDimensions - Bramlage Scientific GmbH 21 Feb 2017

Scientists map vast spider web of cancer proteins to reveal new drug targets

Scientists at Winship Cancer Institute of Emory University have mapped a vast spider web of interactions between proteins in lung cancer cells, as part of an effort to reach what was considered "undruggable."

17 Feb 2017

Biomarker News and Research

Further Reading

Researchers identify protein biomarker linked to prognosis in high-grade serous ovarian cancer

ESMO announces takeover of Targeted Anticancer Therapies Congress series

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

New drug-like compound shows potential to treat symptoms of lupus

Researchers uncover new genetic clues linked to autoimmune kidney disease

Altered distribution of cerebrospinal fluid can predict autism risk in infants

International consortium aims to improve therapeutic options for diabetes-induced kidney disease

Michigan Medicine opens first clinic in the United States that focuses on prostate cancer risk

Medicaid expansion improves health, financial benefits for many low-income Ohioans

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Researchers identify genomic biomarker in nasal passage that can accurately detect lung cancer

New test could accelerate development of better treatments for Motor Neuron Disease

Researchers reveal biological pathways involved in diabetic kidney disease

Alterations in brain connectivity can aid diagnosis and prediction of outcomes in mTBI patients

New clinical practice guideline addresses testing of molecular biomarkers in colorectal cancer patients

Researchers find novel, non-invasive approach for diagnosis and prognosis of prostate cancer

Cocaine addiction may disrupt iron regulation in the brain, study finds

High levels of biomarker linked to poor prognosis in African-Americans with triple-negative breast cancer

microDimensions launches new version of high precision whole slide alignment software

Scientists map vast spider web of cancer proteins to reveal new drug targets

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

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