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SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers evaluate the feasibility of tonsil epithelial cell-derived organoids as an ex vivo model for studying SARS-CoV-2 infection.

15 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

New research has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children.

14 Mar 2022

Researchers find unusual way of stabilizing cancer-suppressing protein

The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now found an unusual way of stabilizing the protein and making it more potent.

14 Mar 2022

Scientists map key molecular changes during mouse embryogenesis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

14 Mar 2022

New smartphone app can calculate users’ genetic risk for coronary artery disease

A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD) - and found that users at high risk sought out appropriate medication after using the app.

14 Mar 2022

Can wearables transform the future of healthcare?

In partnership with SLAS 2022, we spoke to Professor Michael Snyder about his latest research that investigates wearables and their future within healthcare.

From Society for Laboratory Automation and Screening (SLAS) 14 Mar 2022

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers demonstrate enhanced loss-of-function editing of CRISPR/Cas9 in human cells.

14 Mar 2022

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes DNA sequencing possible.

12 Mar 2022

At-home test for influenza is as accurate as rapid diagnostic testing in clinical settings

Home-based, self-administered tests for influenza are comparable in accuracy to rapid diagnostic tests in clinical settings, according to a recently published, peer-reviewed study.

11 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Antibiotic-resistant bacterial infections are difficult to treat and cause more than a million annual deaths worldwide, especially in hospitalized patients with pneumonia, bloodstream infections, urinary tract infections, or abdominal infections.

11 Mar 2022

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Two multi-institutional teams led by Weill Cornell Medicine scientists have been awarded grant support from the Starr Cancer Consortium. Both grants will fund work applying new technologies to develop more detailed knowledge of tumor biology, with one team focusing on Hodgkin lymphoma and the other on the purity of tumor samples on pathology slides.

10 Mar 2022

Origins and evolutions of SARS-CoV-2 Alpha variant in the UK

In a new study, researchers presented the origins and evolution of the SARS-CoV-2 lineage B.1.1.7 in the United Kingdom.

10 Mar 2022

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

New research discusses the role of mutations in the receptor-binding domain of the spike protein in the generation of antibody resistance and loss of vaccine efficacy.

10 Mar 2022

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

A recent study was based on Mendelian randomization analyses conducted between high levels of numerous blood proteins and COVID-19.

9 Mar 2022

Genome News and Research

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers receive grant to find answers to taste loss in COVID patients

Using mRNA to introduce gene editor into human muscle stem cells

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

Researchers find unusual way of stabilizing cancer-suppressing protein

Scientists map key molecular changes during mouse embryogenesis

New smartphone app can calculate users’ genetic risk for coronary artery disease

Can wearables transform the future of healthcare?

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

At-home test for influenza is as accurate as rapid diagnostic testing in clinical settings

Novel genetic relationships with severe SARS-CoV-2

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Origins and evolutions of SARS-CoV-2 Alpha variant in the UK

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

CRIPSR identifies cell-type-specific ACE2 modifiers

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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