Genetic News and Research

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pSivida intensifies research activities

Following extremely encouraging Phase IIa clinical trial results showing successful tumor regression and safety in man, nanotechnology pioneer pSivida Limited is intensifying development of its fully patented invention of nanostructured bioactive, biodegradable and biocompatible silicon (BioSilicon™) for multiple potential healthcare applications.

21 Mar 2005

New findings about the spread of HIV in the UK

Contrary to the prevailing belief that the HIV epidemic in the UK can be traced back to one source, a new study by Oxford and London scientists suggests that HIV spread via at least six independent virus introductions and subsequent transmission chains.

21 Mar 2005

African genome research given impetus

Millions of victims in Africa, die each year from preventable diseases like tuberculosis and malaria and researchers say only a relatively small proportion of money is spent on developing vaccines, much more is spent on drugs aimed at tackling diseases more prevalent among rich, Western consumers.

21 Mar 2005

ParAllele BioScience announces key patent issuance

ParAllele BioScience has announced the issuance by the U.S. Patent Office of a key patent (6,858,412) covering its Molecular Inversion Probe (MIP) technology. The patent is owned by Stanford University and is exclusively licensed to ParAllele.

21 Mar 2005

Oral hygiene during preschool years can mean a lifetime of good oral health

Providing proper care and oral hygiene during preschool years can mean a lifetime of good oral health, according to a recent article in the January/February issue of General Dentistry, clinical, peer-reviewed journal of the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing education.

21 Mar 2005

Why respiratory viral infections are often more severe in people with asthma

Lung cells from asthma sufferers fail to invoke critical anti-viral defenses when infected with the common cold virus, according to a study in the March 21 issue of The Journal of Experimental Medicine. These results could help explain why respiratory viral infections are often more severe in people with asthma and how infection can trigger asthma attacks.

21 Mar 2005

Genomic analysis may one day be a primary diagnostic tool for physicians deciding on a course of treatment for trauma

The researchers showed that state-of-the-art techniques for rapidly analyzing changes in activity of all human genes will likely produce useful insights into the health of critically ill patients. The findings, which are available online and will be published in the March 29 issue of the Proceedings of the National Academy of Sciences, make it possible for physicians to begin answering important questions about critical care through genomic analysis.

21 Mar 2005

Chemists say they have identified a gene that appears to play a key role in the development of type 1 diabetes

In the current study, the researchers focused on the formation of the MIF protein (macrophage migration inhibitory factor), a proinflammatory protein that they showed in previous studies is elevated in diabetic animals and may be involved in the cascade of immunological events that leads to the destruction of the pancreas and the subsequent onset of type 1 diabetes.

21 Mar 2005

RNA loops and knots guide genetic modifications

University of Connecticut Health Center scientist, Robert Reenan, has uncovered new rules of RNA recoding - a genetic editing method cells use to expand the number of proteins assembled from a single DNA code.

21 Mar 2005

Genetically modified plants are to be used to fight against HIV, tuberculosis, diabetes and rabies

Genetically modified (GM) plants are to be used to grow vaccines for use in the worldwide fight against HIV, tuberculosis, diabetes and rabies thanks to a grant of 12 million euros from the EU’s Sixth Framework Programme (FP6).

21 Mar 2005

Unique variant of HIV that is resistant to multiple classes of antiretroviral drugs

Researchers have identified a patient with a unique variant of HIV that is resistant to multiple classes of antiretroviral drugs and associated with the rapid development of AIDS, reporting their findings in this week’s issue of The Lancet.

21 Mar 2005

Major milestone in identifying and creating a register of genes involved in multiple sclerosis

For the first time in this disease area, researchers at the SGI have identified 80 genes involved in the inflammatory and neuro-degenerative pathways of MS, based on a 40% genome scan comparing the genetic profile of a total of 1,800 people with MS and healthy individuals in different populations.

17 Mar 2005

Public concerns show need for independent fertility regulation as great as ever

The public concerns and future developments which underpin the need for ongoing independent regulation of fertility treatment and research were spelt out in a keynote speech by Angela McNab, Chief Executive of the Human Fertilisation and Embryology Authority, at the HFEA’s annual conference this week (15 March).

16 Mar 2005

Dental researchers map the gene that causes dentinogenesis imperfecta

Dental researchers at The University of Texas Health Science Center are the first in the world to successfully map the gene that causes dentinogenesis imperfecta (DGI) Type III, a disease that affects tooth density and color and over time can cause teeth to wear to the gum line.

16 Mar 2005

RNAi Consortium to accelerate genetic research

Whitehead Institute has joined ten other leading biomedical organizations in an $18 million, three-year public-private consortium that will create a comprehensive library of gene inhibitors to be made available to the entire scientific community.

16 Mar 2005

New center focuses on rare Batten disease

For children with Batten disease and their families, the cruelty of the disease, which robs children of their sight, their cognitive faculties and finally their lives, is made worse by the hunt for a doctor experienced at recognizing and treating patients.

16 Mar 2005

Mountaineering doctors hike medicine to new heights with Xtreme Everest

Doctors working at the edge of extreme are set to climb the world’s tallest mountain to look death in the face – and take its pulse. The medical research team will make the first ever measurements of blood oxygen in the ‘death zone’, at altitudes above 8,000 metres where the human body has struggled - and frequently failed - to survive.

16 Mar 2005

Time for ethical reflection is before experimentation begins

The time for ethical reflection is before experimentation begins, especially in the case of potential new methods for creating human embryos for research, according to bioethicists from Wake Forest University Baptist Medical Center and the Mayo Clinic in the spring issue of Ethics & Medicine.

16 Mar 2005

Diabetes Busting Burgers!

Chemists with the U.S. Department of Agriculture recently presented a preliminary report to the 229th national meeting of the American Chemical Society, in which they say they have discovered a form of soluble cellulose that, if added to high-fat food. The new finding could soon benefit people who regularly eat fast-foods that are high in fat.

16 Mar 2005

Aspirin use appears to reduce the incidence of colon polyps

The association between regular aspirin use and a reduced risk of precancerous colon polyps may be strongest in those with particular genetic variants.

15 Mar 2005